XPC (NM_001145769) Human 3' UTR Clone

CAT#: SC210028

3`UTR clone of xeroderma pigmentosum complementation group C (XPC) transcript variant 2 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: XPC
• Synonyms: RAD4; XP3; XPCC
• ACCN: NM_001145769
• Insert Size: 809 bp
• Sequence Data:
  Insert Sequence

  >SC210028 3'UTR clone of NM_001145769
  The sequence shown below is from the reference sequence of NM_001145769. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  CTGTTCCCATTTGAGCAGCTGTGAGCTGAGCGCCCACTAGAGGGGCACCCACCAGTTGCTGCTGCCCCAC
  TACAGGCCCCACACCTGCCCTGGGCATGCCCAGCCCCTGGTGGTGGGGGCTTCTCTGCTGAGAAGGCAAA
  CTGAGGCAGCATGCACGGAGGCGGGGTCAGGGGAGACGAGGCCAAGCTGAGGAGGTGCTGCAGGTCCCGT
  CTGGCTCCAGCCCTTGTCAGATTCACCCAGGGTGAAGCCTTCAAAGCTTTTTGCTACCAAAGCCCACTCA
  CCCTTTGAGCTACAGAACACTTTGCTAGGAGATACTCTTCTGCCTCCTAGACCTGTTCTTTCCATCTTTA
  GAAACATCAGTTTTTGTATGGAAGCCACCGGGAGATTTCTGGATGGTGGTGCATCCGTGAATGCGCTGAT
  CGTTTCTTCCAGTTAGAGTCTTCATCTGTCCGACAAGTTCACTCGCCTCGGTTGCGGACCTAGGACCATT
  TCTCTGCAGGCCACTTACCTTCCCCTGAGTCAGGCTTACTAATGCTGCCCTCACTGCCTCTTTGCAGTAG
  GGGAGAGAGCAGAGAAGTACAGGTCATCTGCTGGGATCTAGTTTTCCAAGTAACATTTTGTGGTGACAGA
  AGCCTAAAAAAAGCTAAAATCAGGAAAGAAAAGGAAAAATACGAATTGAAAATTAAGGAAATGTTAGTAA
  AATAGATGAGTGTTAAACTAGATTGTATTCATTACTAGATAAAATGTATAAAGCTCTCTGTACTAAGGAG
  AAATGACTTTTATAACATTTTGAGAAAATAATAAAGCAT
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

• RefSeq: NM_001145769.1
• Summary: 'The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017]'
• Locus ID: 7508