eIF4GII (EIF4G3) (NM_003760) Human 3' UTR Clone

CAT#: SC210594

3`UTR clone of eukaryotic translation initiation factor 4 gamma 3 (EIF4G3) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: EIF4G3
• Synonyms: eIF-4G 3; eIF4G 3; eIF4GII
• ACCN: NM_003760
• Insert Size: 860
• Sequence Data:
  Insert Sequence

  >SC210594 3'UTR clone of NM_003760
  The sequence shown below is from the reference sequence of NM_003760. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  GGAAGCAGAAGAGGAGTCTGAGGATAACTAAAACTTCAAATACACAAAATGAAACAAAAGAAACAATTTA
  AGTATTTTTTTAAAAAGTTTCACGTCTTCGCCAATCACAGTGCAGCAAGGCCAATTCTCGCAGAAACCCC
  CACGTGTGCACGAGTGGGAGAGGGGAAAGAGAAAAAAAGGTGATCATGGAGGAAAAAGGTACTGGATAAA
  AGTAAACTTCAAACCTTAGGGCGGGAGCACTAAAACCAAAATACATGTATTATTTATAGAAAATATTTTC
  TGTTTTAATCTTTTCTTTTTAAACAAGGACTCATACTTAAAAAAATGTTTAGCAAAAAAAAAAAAAGTTG
  AGAACTTTTAATTTATTTTAAGGACTGCAAATGCCAGTGTAATTTTTTAATTTGCAGTTTCTGTAAACAA
  CTTGTATAATAGAAAAGCAGAGAAATAAATTTCCCTCCCCTTCAAGATGCACCTCATGTTTGTTTTAAGG
  TATAGCATTTAGTCCAGATTTGAGAAAGTTTGGGGTGAACAAGGTAAGAAAGATTTTTTTTTTTTTGGCA
  TCAAATCTTTCTGCCTGCCTCTCAGCTTGCTTCAGAAAATTTAAAAAATCACAATAGTAATCAAAACATA
  CATAACATTGAAACAGAAGGAAATGCTGTGGACCACAGAACTCCAAGAATTGTTTAAAAAAAAAAAAGTG
  CTACCCTGAGAAAAGTACTCTTAATACTCTTGAAATCTTTAGAGCAACTTTAAGGCTTGTAAATACATAG
  AACAAATATTTAAAAAAACAAAAAGAAATTGACTCAGTACTATTTCTTTTCACTTTGAAAATATAAAGAA
  CAAAATAAAGACAAACATTG
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_003760.3
• Summary: The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p. [provided by RefSeq, May 2016]
• Locus ID: 8672