LKB1 (STK11) (NM_000455) Human 3' UTR Clone

CAT#: SC210625

3`UTR clone of serine/threonine kinase 11 (STK11) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: STK11
• Synonyms: hLKB1; LKB1; PJS
• ACCN: NM_000455
• Insert Size: 903 bp
• Sequence Data:
  Insert Sequence

  >SC210625 3'UTR clone of NM_000455
  The sequence shown below is from the reference sequence of NM_000455. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  CCAGCAGCAAGATCCGCCGGCTGTCGGCCTGCAAGCAGCAGTGAGGCTGGCCGCCTGCAGCCCGTGTCCA
  GGAGCCCCGCCAGGTGCCCGCGCCAGGCCCTCAGTCTTCCTGCCGGTTCCGCCCGCCCTCCCGGAGAGGT
  GGCCGCCATGCTTCTGTGCCGACCACGCCCCAGGACCTCCGGAGCGCCCTGCAGGGCCGGGCAGGGGGAC
  AGCAGGGACCGGGCGCAGCCCTCCCCCCTCGGCCGCCCGGCAGTGCACGCGGCTTGTTGACTTCGCAGCC
  CCGGGCGGAGCCTTCCCGGGCGGGCGTGGGAGGAGGGAGGCGGCCTCCATGCACTTTATGTGGAGACTAC
  TGGCCCCGCCCGTGGCCTCGTGCTCCGCAGGGCGCCCAGCGCCGTCCGGCGGCCCCGCCGCAGACCAGCT
  GGCGGGTGTGGAGACCAGGCTCCTGACCCCGCCATGCATGCAGCGCCACCTGGAAGCCGCGCGGCCGCTT
  TGGTTTTTTGTTTGGTTGGTTCCATTTTCTTTTTTTCTTTTTTTTTTTAAGAAAAAATAAAAGGTGGATT
  TGAGCTGTGGCTGTGAGGGGTGTTTGGGAGCTGCTGGGTGGCAGGGGGGCTGTGGGGTCGGGCTCACGTC
  GCGGCCGCCTTTGCGCTCTCGGGTCACCCTGCTTTGGCGGCCCGGCCGGAGGGCAGGACCCTCACCTCTC
  CCCCAAGGCCACTGCGCTCTTGGGACCCCAGAGAAAACCCGGAGCAAGCAGGAGTGTGCGGTCAATATTT
  ATATCATCCAGAAAAGAAAAACACGAGAAACGCCATCGCGGGATGGTGCAGACGCGGCGGGGACTCGGAG
  GGTGCCGTGCGGGCGAGGCCGCCCAAATTTGGCAATAAATAAAGCTTGGGAAGCTTGGACCTG
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

• RefSeq: NM_000455.4
• Summary: 'This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]'
• Locus ID: 6794