TTF1 (NKX2-1) (NM_001079668) Human 3' UTR Clone

CAT#: SC210900

3`UTR clone of NK2 homeobox 1 (NKX2-1) transcript variant 1 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: NKX2-1
• Synonyms: BCH; BHC; NK-2; NKX2.1; NKX2A; NMTC1; T/EBP; TEBP; TITF1; TTF-1; TTF1
• ACCN: NM_001079668
• Insert Size: 893 bp
• Sequence Data:
  Insert Sequence

  >SC210900 3'UTR clone of NM_001079668
  The sequence shown below is from the reference sequence of NM_001079668. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  ATGTCCTGCTCCACCTTGCTATACGGTCGGACCTGGTGAGAGGACGCCGGGCCGGCCCTAGCCCAGCGCT
  CTGCCTCACCGCTTCCCTCCTGCCCGCCACACAGACCACCATCCACCGCTGCTCCACGCGCTTCGACTTT
  TCTTAACAACCTGGCCGCGTTTAGACCAAGGAACAAAAAAACCACAAAGGCCAAACTGCTGGACGTCTTT
  CTTTTTTTCCCCCCCTAAAATTTGTGGGTTTTTTTTTTTAAAAAAAGAAAATGAAAAACAACCAAGCGCA
  TCCAATCTCAAGGAATCTTTAAGCAGAGAAGGGCATAAAACAGCTTTGGGGTGTCTTTTTTTGGTGATTC
  AAATGGGTTTTCCACGCTAGGGCGGGGCACAGATTGGAGAGGGCTCTGTGCTGACATGGCTCTGGACTCT
  AAAGACCAAACTTCACTCTGGGCACACTCTGCCAGCAAAGAGGACTCGCTTGTAAATACCAGGATTTTTT
  TTTTTTTTTGAAGGGAGGACGGGAGCTGGGGAGAGGAAAGAGTCTTCAACATAACCCACTTGTCACTGAC
  ACAAAGGAAGTGCCCCCTCCCCGGCACCCTCTGGCCGCCTAGGCTCAGCGGCGACCGCCCTCCGCGAAAA
  TAGTTTGTTTAATGTGAACTTGTAGCTGTAAAACGCTGTCAAAAGTTGGACTAAATGCCTAGTTTTTAGT
  AATCTGTACATTTTGTTGTAAAAAGAAAAACCACTCCCAGTCCCCAGCCCTTCACATTTTTTATGGGCAT
  TGACAAATCTGTGTATATTATTTGGCAGTTTGGTATTTGCGGCGTCAGTCTTTTTCTGTTGTAACTTATG
  TAGATATTTGGCTTAAATATAGTTCCTAAGAAGCTTCTAATAAATTATACAAA
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

• RefSeq: NM_001079668.2
• Summary: 'This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014]'
• Locus ID: 7080