DUSP4 (NM_057158) Human 3' UTR Clone
CAT#: SC211188
3`UTR clone of dual specificity phosphatase 4 (DUSP4) transcript variant 2 for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | DUSP4 |
Synonyms | HVH2; MKP-2; MKP2; TYP |
ACCN | NM_057158 |
Insert Size | 808 bp |
Sequence Data |
>SC211188 3'UTR clone of NM_057158
The sequence shown below is from the reference sequence of NM_057158. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC CCATCACCACCTCTCCCAGCTGTTAGAGCCGCCCTGGGGGCCCCAGAACCAGAGCTGGCTCCCAGCAAGG GTAGGACGGGCCGCATGCGGGCAGAAAGTTGGGACTGAGCAGCTGGGAGCAGGCGACCGAGCTCCTTCCC CATCATTTCTCCTTGGCCAACGACGAGGCCAGCCAGAATGGCAATAAGGACTCCGAATACATAATAAAAG CAAACAGAACACTCCAACTTAGAGCAATAACGGCTGCCGCAGCAGCCAGGGAAGACCTTGGTTTGGTTTA TGTGTCAGTTTCACTTTTCCGATAGAAATTTCTTACCTCATTTTTTTAAGCAGTAAGGCTTGAAGTGATG AAACCCACAGATCCTAGCAAATGTGCCCAACCAGCTTTACTAAAGGGGGAGGAAGGGAGGGCAAAGGGAT GAGAAGACAAGTTTCCCAGAAGTGCCTGGTTCTGTGTACTTGTCCCTTTGTTGTCGTTGTTGTAGTTAAA GGAATTTCATTTTTTAAAAGAAATCTTCGAAGGTGTGGTTTTCATTTCTCAGTCACCAACAGATGAATAA TTATGCTTAATAATAAAGTATTTATTAAGACTTTCTTCAGAGTATGAAAGTACAAAAAGTCTAGTTACAG TGGATTTAGAATATATTTATGTTGATGTCAAACAGCTGAGCACCGTAGCATGCAGATGTCAAGGCAGTTA GGAAGTAAATGGTGTCTTGTAGATATGTGCAAGGTAGCATGATGAGCAACTTGAGTTTGTTGCCACTGAG AAGCAGGCGGGTTGGGTGGGAGGAGGAAGAAAGGGAAG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. |
Reference Data | |
RefSeq | NM_057158.2 |
Summary | 'The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported. [provided by RefSeq, Jul 2008]' |
Locus ID | 1846 |
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