OTUD5 (NM_001136158) Human 3' UTR Clone

CAT#: SC211245

3`UTR clone of OTU domain containing 5 (OTUD5) transcript variant 3 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: OTUD5
• Synonyms: DUBA
• ACCN: NM_001136158
• Insert Size: 956
• Sequence Data:
  Insert Sequence

  >SC211245 3'UTR clone of NM_001136158
  The sequence shown below is from the reference sequence of NM_001136158. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  CAAAGTGCACAGAGACCCGCCCCCAGACAAGAGTTGATGGAGACCCAGGGATTGGACACCATCTCCCAAC
  CCCAGGGACTCGGGCAAGGGTGCCGAAGATAGACAAGAGGCACACAGAGACAGACCAACTGGCAGCCAGG
  CAGCCCCAGAGGAGAGAGACATTCAGACAGAGGAAAGTCTCCCTGCCCCTCATTCCTTCCAAGATGAGAA
  AAACTTGCCGCCACCCCCCGACACTGATGCCAGGGAGGTGGGAGGAAGAAGTGGGAAATTTCCCTTCCCA
  GTACCCCCAAGAACGTCTGAGCCTTCAATGTTGAATTTTTTCTTTATTAAAATTACTTTTATCTTATAAA
  ATCAACTAATCAAAAATGATATAGACGACAGCACTGGCTCTGTGAAGGTGGCATCTTTCTGGGCAGGCAG
  GCCATGGGGCATGGAGGAGGGTGCAAAGATATGGGTTGCTGTCTTCTGGCCTCCAGCTGCATGGAGGCCG
  GCCCAGGGTCTAGGGTGTGCACTGGGCAAGGGCAGGGCGGCAGGTGTCAGGCCGGCTTGGACAATGAAAC
  CCTGACCTTGCTGCATTCCTTTTGCTTCCACCACCACTAGCTTCTTTGGAATCTTGGGGTGGGGGTCATC
  TTTGGGGATTATGGCTGCCACCCGGGATTTGAGTGTAGGGAGTGTGGGAGCAGCCTTGGCAGATGGGGCA
  CCCGTGCCCTGCAGGTGTTGACAAGATCCGCCATCTGTAATGTCCTTGGCACAATAAAACCAAATGTCAG
  TTTCCCTGAGCGACTCTGTTCTGTGTGGGGCAGGGGTTGGGCGGGCCTCTGGGCAGAGGATGCAATGGCA
  CGGACCTTGGCTTGACCTCAGAGGTGTGAATGCTCTCCAGCAGGGTCTGTCTGGGGGCCTGGAGTTTGTA
  TTTGATTTGCTGCTTATTAAACCTCCTTCTGGACCTATTGCCACTG
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_001136158.1
• Summary: This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008]
• Locus ID: 55593