RYK (NM_002958) Human 3' UTR Clone
CAT#: SC211848
3`UTR clone of RYK receptor-like tyrosine kinase (RYK) transcript variant 2 for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | RYK |
Synonyms | D3S3195; JTK5; JTK5A; RYK1 |
ACCN | NM_002958 |
Insert Size | 1056 |
Sequence Data |
>SC211848 3'UTR clone of NM_002958
The sequence shown below is from the reference sequence of NM_002958. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC CAGTGCCTAACAGAGTTTCATGCAGCCCTGGGGGCCTACGTCTGACTCCTCTCCAATCCCACACCATCAG GAAGAAGGTGCCTGTCGGGGCTCACTTGAAGCCTGTCAGGGATGCTTTGTATCTAACACAACGCCAACAG AAGCACATTTGTCTTCCAGAACACCGTGCCTTAGAAATGCTTTAGAATCTGAACTTTTTAAGACAGACTT AATAATGTGGCATATTTTCTAGATATCACTTTTATTAGGTTGAACTGAAAGGGTTTTTGTAAATTTTTTG GCCAAAATTTTTTAAAACATACTTACTTTGGACTAGGGGTACATTCTTACAAAATAAATAAACAGTTTTT AAAATTGTTTAGACACAGATATTTGGAATTAGCTATCTTAGTGCCAACTGCTTTTTATTTTTTTACTTCA TCAAGGTGATGTAAGTGACTCACCTTTAAAGTTTTTTTAGTGTTATTTTTTATCACTACTCTGGGAAATG GTTTGTCTTCAAGATGCAATACTTTTCTTAGTAAAGGAAAAACAGCATAAAAAGATACCTGGTCTGCCTT GTACAAGAAAAGGCAATATTAGAGGAAGAAAATTTAAAGAAAAGCTAGAGGAAAAAAAAATTTTTTTAAA AATACTTATTAGAAGCAAACTGCCCTTGCATGGAAAACTGTTTATTTTTTTCAGTGAAAAGGAATTCTGC TTTCGTGTTTTTGGGAAAGCAGGAACTGAGTTCATTACATCTTTAATTTGGCAGAAATTAGCCTTTCTGT GAACCAGATGTGGTTTGGGGCAGATCTGTAGTAAACAATGGTGATTTTATTTATTTTTACTCTCTGGAAA AGGAGATAATACAATTCCAGAAAGTGAACTCATATTTCTAAGGTTAAGATTCCCTTTTATTGCACCTAGA ATAGTGCTATGCACAGAGCGGGTGCTTGAGTTGTTGTCGTTTTTTGTTTGTTTTTTAAATGTAAACTGGT AAATTTTGTGCTTATCTTCAAGGCTGGCTTAAGTATAAAATTGTTTTTTAAACACTTGAAAAATTAAAGG ATTTGT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_002958.3 |
Summary | The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2012] |
Locus ID | 6259 |
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