OTX2 (NM_172337) Human 3' UTR Clone

CAT#: SC212019

3`UTR clone of orthodenticle homeobox 2 (OTX2) transcript variant 2 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: OTX2
• Synonyms: CPHD6; MCOPS5
• ACCN: NM_172337
• Insert Size: 1036 bp
• Sequence Data:
  Insert Sequence

  >SC212019 3'UTR clone of NM_172337
  The sequence shown below is from the reference sequence of NM_172337. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  AGATCAGACATCCTCGTGGAAATTCCAGGTTTTGTGAAGACCTGTAGAACCTCTTTTTGTGGGTGATTTT
  TAAATATACTGGGCTGGACATTCCAGTTTTAGCCAGGCATTGGTTAAAAGAGTTAGATGGGATGATGCTC
  AGACTCATCTGATCAAAGTTCCGAGAGGCATAGAAGGAAAAACGAAGGGCCTTAGAGGGGCCTACAAACC
  AGCAACATGAAATGGACAAACCAATCTGCTTAAGATCCTGTCATAGTTTTAGATCATTGGTTATCCTGAT
  TTGCAAAGTGATCAAAAGCATTCTAGCCATGTGCAACCAAACACCACCAAAAATAAAATCAAACAAAACT
  AAGTTGTGAAGGAAGGGAGGGAAGGTCATAGCCTTCTTAAGCAGAGGTGTTCCATTGTTTTAGCCAATCC
  TTGGTTGAATCTTAGGAATGAACAGTGTCTCAAGCTCATTCACGTTTCATGACCAACTGGTAGTTGGCAC
  TGAAAAAACTTTTCAGGGCTGTGTGAATTGTGTGACTGATTGTCCTAGATGCACTACTTTATTTAAAAAA
  TAATGTTCATAAGGAGTCAATATGTAGTTTAAGAGACAATCAGTGTGTGTCTTATAAATGGTACATCTGT
  GGTTTTTAATCTGTGCTAGACTTCAAAACTGTGATCTCCTGTTATTGTATGCAACCTTGAACTCCACCTC
  TGCAGGGGTTCTTCTGTGATTAAATAGGTTATAATTATAAGCAAAATTCAGAGCAACTGAGTACTGATCT
  AAAAAGATTACCTTTGGCTGGAGGTGAGCTGCACTGAAACTTTACGACAAAATGTCTCTGGACAAAGAGA
  GTCAGAGAAGAGAAGCAAAAGGACACTAATTCATCTGTAATTTACTGTTGGTAAGCCTAGCAGTAAAGAG
  ACATTGGTCAATTGCTCTGACCCTGATGAATTATTAAACTGAGATCATTGTCGTTTATGCTTGCAGATGT
  TAAATGGAAAAGTTATATATGCATAAACCTTTTCTTCCTGGATTTGGCAGATATGT
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

• RefSeq: NM_172337.1
• Summary: 'This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012]'
• Locus ID: 5015