TGF beta 3 (TGFB3) (NM_003239) Human 3' UTR Clone
CAT#: SC212349
3`UTR clone of transforming growth factor beta 3 (TGFB3) for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | TGFB3 |
Synonyms | ARVD; ARVD1; LDS5; RNHF; TGF-beta3 |
ACCN | NM_003239 |
Insert Size | 1129 bp |
Sequence Data |
>SC212349 3'UTR clone of NM_003239
The sequence shown below is from the reference sequence of NM_003239. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC AGCTCTCCAACATGGTGGTGAAGTCTTGTAAATGTAGCTGAGACCCCACGTGCGACAGAGAGAGGGGAGA GAGAACCACCACTGCCTGACTGCCCGCTCCTCGGGAAACACACAAGCAACAAACCTCACTGAGAGGCCTG GAGCCCACAACCTTCGGCTCCGGGCAAATGGCTGAGATGGAGGTTTCCTTTTGGAACATTTCTTTCTTGC TGGCTCTGAGAATCACGGTGGTAAAGAAAGTGTGGGTTTGGTTAGAGGAAGGCTGAACTCTTCAGAACAC ACAGACTTTCTGTGACGCAGACAGAGGGGATGGGGATAGAGGAAAGGGATGGTAAGTTGAGATGTTGTGT GGCAATGGGATTTGGGCTACCCTAAAGGGAGAAGGAAGGGCAGAGAATGGCTGGGTCAGGGCCAGACTGG AAGACACTTCAGATCTGAGGTTGGATTTGCTCATTGCTGTACCACATCTGCTCTAGGGAATCTGGATTAT GTTATACAAGGCAAGCATTTTTTTTTTTTTTTTAAAGACAGGTTACGAAGACAAAGTCCCAGAATTGTAT CTCATACTGTCTGGGATTAAGGGCAAATCTATTACTTTTGCAAACTGTCCTCTACATCAATTAACATCGT GGGTCACTACAGGGAGAAAATCCAGGTCATGCAGTTCCTGGCCCATCAACTGTATTGGGCCTTTTGGATA TGCTGAACGCAGAAGAAAGGGTGGAAATCAACCCTCTCCTGTCTGCCCTCTGGGTCCCTCCTCTCACCTC TCCCTCGATCATATTTCCCCTTGGACACTTGGTTAGACGCCTTCCAGGTCAGGATGCACATTTCTGGATT GTGGTTCCATGCAGCCTTGGGGCATTATGGGTTCTTCCCCCACTTCCCCTCCAAGACCCTGTGTTCATTT GGTGTTCCTGGAAGCAGGTGCTACAACATGTGAGGCATTCGGGGAAGCTGCACATGTGCCACACAGTGAC TTGGCCCCAGACGCATAGACTGAGGTATAAAGACAAGTATGAATATTACTCTCAAAATCTTTGTATAAAT AAATATTTTTGGGGCATCCTGGATGATTTCATCTTCTGGAATATTGTTTCTAGAACAGTAAAAGCCTTAT TCTAAGGTG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. |
Reference Data | |
RefSeq | NM_003239.2 |
Summary | 'This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1. [provided by RefSeq, Aug 2016]' |
Locus ID | 7043 |
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