TGF beta 3 (TGFB3) (NM_003239) Human 3' UTR Clone

CAT#: SC212349

3`UTR clone of transforming growth factor beta 3 (TGFB3) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: TGFB3
• Synonyms: ARVD; ARVD1; LDS5; RNHF; TGF-beta3
• ACCN: NM_003239
• Insert Size: 1129 bp
• Sequence Data:
  Insert Sequence

  >SC212349 3'UTR clone of NM_003239
  The sequence shown below is from the reference sequence of NM_003239. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  AGCTCTCCAACATGGTGGTGAAGTCTTGTAAATGTAGCTGAGACCCCACGTGCGACAGAGAGAGGGGAGA
  GAGAACCACCACTGCCTGACTGCCCGCTCCTCGGGAAACACACAAGCAACAAACCTCACTGAGAGGCCTG
  GAGCCCACAACCTTCGGCTCCGGGCAAATGGCTGAGATGGAGGTTTCCTTTTGGAACATTTCTTTCTTGC
  TGGCTCTGAGAATCACGGTGGTAAAGAAAGTGTGGGTTTGGTTAGAGGAAGGCTGAACTCTTCAGAACAC
  ACAGACTTTCTGTGACGCAGACAGAGGGGATGGGGATAGAGGAAAGGGATGGTAAGTTGAGATGTTGTGT
  GGCAATGGGATTTGGGCTACCCTAAAGGGAGAAGGAAGGGCAGAGAATGGCTGGGTCAGGGCCAGACTGG
  AAGACACTTCAGATCTGAGGTTGGATTTGCTCATTGCTGTACCACATCTGCTCTAGGGAATCTGGATTAT
  GTTATACAAGGCAAGCATTTTTTTTTTTTTTTTAAAGACAGGTTACGAAGACAAAGTCCCAGAATTGTAT
  CTCATACTGTCTGGGATTAAGGGCAAATCTATTACTTTTGCAAACTGTCCTCTACATCAATTAACATCGT
  GGGTCACTACAGGGAGAAAATCCAGGTCATGCAGTTCCTGGCCCATCAACTGTATTGGGCCTTTTGGATA
  TGCTGAACGCAGAAGAAAGGGTGGAAATCAACCCTCTCCTGTCTGCCCTCTGGGTCCCTCCTCTCACCTC
  TCCCTCGATCATATTTCCCCTTGGACACTTGGTTAGACGCCTTCCAGGTCAGGATGCACATTTCTGGATT
  GTGGTTCCATGCAGCCTTGGGGCATTATGGGTTCTTCCCCCACTTCCCCTCCAAGACCCTGTGTTCATTT
  GGTGTTCCTGGAAGCAGGTGCTACAACATGTGAGGCATTCGGGGAAGCTGCACATGTGCCACACAGTGAC
  TTGGCCCCAGACGCATAGACTGAGGTATAAAGACAAGTATGAATATTACTCTCAAAATCTTTGTATAAAT
  AAATATTTTTGGGGCATCCTGGATGATTTCATCTTCTGGAATATTGTTTCTAGAACAGTAAAAGCCTTAT
  TCTAAGGTG
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

• RefSeq: NM_003239.2
• Summary: 'This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1. [provided by RefSeq, Aug 2016]'
• Locus ID: 7043