Activin Receptor Type IA (ACVR1) (NM_001105) Human 3' UTR Clone
CAT#: SC212415
3`UTR clone of activin A receptor type I (ACVR1) transcript variant 1 for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | ACVR1 |
Synonyms | ACTRI; ACVR1A; ACVRLK2; ALK2; FOP; SKR1; TSRI |
ACCN | NM_001105 |
Insert Size | 1109 bp |
Sequence Data |
>SC212415 3'UTR clone of NM_001105
The sequence shown below is from the reference sequence of NM_001105. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC CTCGACAAATTGAAAACTGACTGTTGACATTTTCATAGTGTCAAGAAGGAAGATTTGACGTTGTTGTCAT TGTCCAGCTGGGACCTAATGCTGGCCTGACTGGTTGTCAGAATGGAATCCATCTGTCTCCCTCCCCAAAT GGCTGCTTTGACAAGGCAGACGTCGTACCCAGCCATGTGTTGGGGAGACATCAAAACCACCCTAACCTCG CTCGATGACTGTGAACTGGGCATTTCACGAACTGTTCACACTGCAGAGACTAATGTTGGACAGACACTGT TGCAAAGGTAGGGACTGGAGGAACACAGAGAAATCCTAAAAGAGATCTGGGCATTAAGTCAGTGGCTTTG CATAGCTTTCACAAGTCTCCTAGACACTCCCCACGGGAAACTCAAGGAGGTGGTGAATTTTTAATCAGCA ATATTGCCTGTGCTTCTCTTCTTTATTGCACTAGGAATTCTTTGCATTCCTTACTTGCACTGTTACTCTT AATTTTAAAGACCCAACTTGCCAAAATGTTGGCTGCGTACTCCACTGGTCTGTCTTTGGATAATAGGAAT TCAATTTGGCAAAACAAAATGTAATGTCAGACTTTGCTGCATTTTACACATGTGCTGATGTTTACAATGA TGCCGAACATTAGGAATTGTTTATACACAACTTTGCAAATTATTTATTACTTGTGCACTTAGTAGTTTTT ACAAAACTGCTTTGTGCATATGTTAAAGCTTATTTTTATGTGGTCTTATGATTTTATTACAGAAATGTTT TTAACACTATACTCTAAAATGGACATTTTCTTTTATTATCAGTTAAAATCACATTTTAAGTGCTTCACAT TTGTATGTGTGTAGACTGTAACTTTTTTTCAGTTCATATGCAGAACGTATTTAGCCATTACCCACGTGAC ACCACCGAATATATTACTGATTTAGAAGCAAAGATTTCAGTAGAATTTTAGTCCTGAACGCTACGGGGAA AATGCATTTTCTTCAGAATTATCCATTACGTGCATTTAAACTCTGCCAGAAAAAAATAACTATTTTGTTT TAATCTACTTTTTGTATTTAGTAGTTATTTGTATAAATTAAATAAACTGTTTTCAAGTC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. |
Reference Data | |
RefSeq | NM_001105.4 |
Summary | 'Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. [provided by RefSeq, Jul 2008]' |
Locus ID | 90 |
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