CARD4 (NOD1) (NM_006092) Human 3' UTR Clone

CAT#: SC212581

3`UTR clone of nucleotide-binding oligomerization domain containing 1 (NOD1) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: NOD1
• Synonyms: CARD4; CLR7.1; NLRC1
• ACCN: NM_006092
• Insert Size: 1110
• Sequence Data:
  Insert Sequence

  >SC212581 3'UTR clone of NM_006092
  The sequence shown below is from the reference sequence of NM_006092. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  GATGAGAAGCGGATTATCTGTTTCTGAGAGGATGCTTTCCTGTTCATGGGGTTTTTGCCCTGGAGCCTCA
  GCAGCAAATGCCACTCTGGGCAGTCTTTTGTGTCAGTGTCTTAAAGGGGCCTGCGCAGGCGGGACTATCA
  GGAGTCCACTGCCTCCATGATGCAAGCCAGCTTCCTGTGCAGAAGGTCTGGTCGGCAAACTCCCTAAGTA
  CCCGCTACAATTCTGCAGAAAAAGAATGTGTCTTGCGAGCTGTTGTAGTTACAGTAAATACACTGTGAAG
  AGACTTTATTGCCTATTATAATTATTTTTATCTGAAGCTAGAGGAATAAAGCTGTGAGCAAACAGAGGAG
  GCCAGCCTCACCTCATTCCAACACCTGCCATAGGGACCAACGGGAGCGAGTTGGTCACCGCTCTTTTCAT
  TGAAGAGTTGAGGATGTGGCACAAAGTTGGTGCCAAGCTTCTTGAATAAAACGTGTTTGATGGATTAGTA
  TTATACCTGAAATATTTTCTTCCTTCTCAGCACTTTCCCATGTATTGATACTGGTCCCACTTCACAGCTG
  GAGACACCGGAGTATGTGCAGTGTGGGATTTGACTCCTCCAAGGTTTTGTGGAAAGTTAATGTCAAGGAA
  AGGATGCACCACGGGCTTTTAATTTTAATCCTGGAGTCTCACTGTCTGCTGGCAAAGATAGAGAATGCCC
  TCAGCTCTTAGCTGGTCTAAGAATGACGATGCCTTCAAAATGCTGCTTCCACTCAGGGCTTCTCCTCTGC
  TAGGCTACCCTCCTCTAGAAGGCTGAGTACCATGGGCTACAGTGTCTGGCCTTGGGAAGAAGTGATTCTG
  TCCCTCCAAAGAAATAGGGCATGGCTTGCCCCTGTGGCCCTGGCATCCAAATGGCTGCTTTTGTCTCCCT
  TACCTCGTGAAGAGGGGAAGTCTCTTCCTGCCTCCCAAGCAGCTGAAGGGTGACTAAACGGGCGCCAAGA
  CTCAGGGGATCGGCTGGGAACTGGGCCAGCAGAGCATGTTGGACACCCCCCACCATGGTGGGCTTGTGGT
  GGCTGCTCCATGAGGGTGGGGGTGATACTACTAGATCACTTGTCCTCTTGCCAGCTCATT
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_006092.2
• Summary: This gene encodes a member of the nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family of proteins. The encoded protein plays a role in innate immunity by acting as a pattern-recognition receptor (PRR) that binds bacterial peptidoglycans and initiates inflammation. This protein has also been implicated in the immune response to viral and parasitic infection. Major structural features of this protein include an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. Mutations in this gene are associated with asthma, inflammatory bowel disease, Behcet disease and sarcoidosis in human patients. [provided by RefSeq, Aug 2017]
• Locus ID: 10392