TL1A (TNFSF15) (NM_005118) Human 3' UTR Clone

CAT#: SC212724

3`UTR clone of tumor necrosis factor (ligand) superfamily member 15 (TNFSF15) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: TNFSF15
• Synonyms: TL1; TL1A; TNLG1B; VEGI; VEGI192A
• ACCN: NM_005118
• Insert Size: 1129
• Sequence Data:
  Insert Sequence

  >SC212724 3'UTR clone of NM_005118
  The sequence shown below is from the reference sequence of NM_005118. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  CTTCTTTGGAGCCTTCTTACTATAGGAGGAGAGCAAATATCATTATATGAAAGTCCTCTGCCACCGAGTT
  CCTAATTTTCTTTGTTCAAATGTAATTATAACCAGGGGTTTTCTTGGGGCCGGGAGTAGGGGGCATTCCA
  CAGGGACAACGGTTTAGCTATGAAATTTGGGGCCCAAAATTTCACACTTCATGTGCCTTACTGATGAGAG
  TACTAACTGGAAAAAGGCTGAAGAGAGCAAATATATTATTAAGATGGGTTGGAGGATTGGCGAGTTTCTA
  AATATTAAGACACTGATCACTAAATGAATGGATGATCTACTCGGGTCAGGATTGAAAGAGAAATATTTCA
  ACACCTTCCTGCTATACAATGGTCACCAGTGGTCCAGTTATTGTTCAATTTGATCATAAATTTGCTTCAA
  TTCAGGAGCTTTGAAGGAAGTCCAAGGAAAGCTCTAGAAAACAGTATAAACTTTCAGAGGCAAAATCCTT
  CACCAATTTTTCCACATACTTTCATGCCTTGCCTAAAAAAAATGAAAAGAGAGTTGGTATGTCTCATGAA
  TGTTCACACAGAAGGAGTTGGTTTTCATGTCATCTACAGCATATGAGAAAAGCTACCTTTCTTTTGATTA
  TGTACACAGATATCTAAATAAGGAAGTATGAGTTTCACATGTATATCAAAAATACAACAGTTGCTTGTAT
  TCAGTAGAGTTTTCTTGCCCACCTATTTTGTGCTGGGTTCTACCTTAACCCAGAAGACACTATGAAAAAC
  AAGACAGACTCCACTCAAAATTTATATGAACACCACTAGATACTTCCTGATCAAACATCAGTCAACATAC
  TCTAAAGAATAACTCCAAGTCTTGGCCAGGCGCAGTGGCTCACACCTGTAATCCCAACACTTTGGGAGGC
  CAAGGTGGGTGGATCATCTAAGGCCGGGAGTTCAAGACCAGCCTGACCAACGTGGAGAAACCCCATCTCT
  ACTAAAAATACAAAATTAGCCGGGCGTGGTAGCGCATGGCTGTAATCCTGGCTACTCAGGAGGCCGAGGC
  AGAAGAATTGCTTGAACTGGGGAGGCAGAGGTTGCGGTGAGCCCAGATCGCGCCATTGCACTCCAGCCTG
  GGTAACAAG
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_005118.2
• Summary: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
• Locus ID: 9966