IL1RA (IL1RN) (NM_173842) Human 3' UTR Clone

CAT#: SC212851

3`UTR clone of interleukin 1 receptor antagonist (IL1RN) transcript variant 1 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: IL1RN
• Synonyms: DIRA; ICIL-1RA; IL-1ra; IL-1ra3; IL-1RN; IL1F3; IL1RA; IRAP; MVCD4
• ACCN: NM_173842
• Insert Size: 1138 bp
• Sequence Data:
  Insert Sequence

  >SC212851 3'UTR clone of NM_173842
  The sequence shown below is from the reference sequence of NM_173842. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  TACTTCCAGGAGGACGAGTAGTACTGCCCAGGCCTGCCTGTTCCCATTCTTGCATGGCAAGGACTGCAGG
  GACTGCCAGTCCCCCTGCCCCAGGGCTCCCGGCTATGGGGGCACTGAGGACCAGCCATTGAGGGGTGGAC
  CCTCAGAAGGCGTCACAAGAACCTGGTCACAGGACTCTGCCTCCTCTTCAACTGACCAGCCTCCATGCTG
  CCTCCAGAATGGTCTTTCTAATGTGTGAATCAGAGCACAGCAGCCCCTGCACAAAGCCCTTCCATGTCGC
  CTCTGCATTCAGGATCAAACCCCGACCACCTGCCCAACCTGCTCTCCTCTTGCCACTGCCTCTTCCTCCC
  TCATTCCACCTTCCCATGCCCTGGATCCATCAGGCCACTTGATGACCCCCAACCAAGTGGCTCCCACACC
  CTGTTTTACAAAAAAGAAAAGACCAGTCCATGAGGGAGGTTTTTAAGGGTTTGTGGAAAATGAAAATTAG
  GATTTCATGATTTTTTTTTTTCAGTCCCCGTGAAGGAGAGCCCTTCATTTGGAGATTATGTTCTTTCGGG
  GAGAGGCTGAGGACTTAAAATATTCCTGCATTTGTGAAATGATGGTGAAAGTAAGTGGTAGCTTTTCCCT
  TCTTTTTCTTCTTTTTTTGTGATGTCCCAACTTGTAAAAATTAAAAGTTATGGTACTATGTTAGCCCCAT
  AATTTTTTTTTTCCTTTTAAAACACTTCCATAATCTGGACTCCTCTGTCCAGGCACTGCTGCCCAGCCTC
  CAAGCTCCATCTCCACTCCAGATTTTTTACAGCTGCCTGCAGTACTTTACCTCCTATCAGAAGTTTCTCA
  GCTCCCAAGGCTCTGAGCAAATGTGGCTCCTGGGGGTTCTTTCTTCCTCTGCTGAAGGAATAAATTGCTC
  CTTGACATTGTAGAGCTTCTGGCACTTGGAGACTTGTATGAAAGATGGCTGTGCCTCTGCCTGTCTCCCC
  CACCGGGCTGGGAGCTCTGCAGAGCAGGAAACATGACTCGTATATGTCTCAGGTCCCTGCAGGGCCAAGC
  ACCTAGCCTCGCTCTTGGCAGGTACTCAGCGAATGAATGCTGTATATGTTGGGTGCAAAGTTCCCTACTT
  CCTGTGACTTCAGCTCTG
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

• RefSeq: NM_173842.1
• Summary: 'The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses, particularly in the acute phase of infection and inflammation. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Aug 2020]'
• Locus ID: 3557