Prostaglandin E Synthase (PTGES) (NM_004878) Human 3' UTR Clone

CAT#: SC213630

3`UTR clone of prostaglandin E synthase (PTGES) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: PTGES
• Synonyms: MGST-IV; MGST1-L1; MGST1L1; MPGES; mPGES-1; PGES; PIG12; PP102; PP1294; TP53I12
• ACCN: NM_004878
• Insert Size: 1300
• Sequence Data:
  Insert Sequence

  >SC213630 3'UTR clone of NM_004878
  The sequence shown below is from the reference sequence of NM_004878. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  TGCAGATCCTCTGGGAAGCGGCCCGCCACCTGTGACCAGCAGCTGATGCCTCCTTGGCCACCAGACCATG
  GGCCAAGAGCCGCCGTGGCTATACCTGGGGACTTGATGTTCCTTCCAGATTGTGGTGGGCCCTGAGTCCT
  GGTTTCCTGGCAGCCTGCTGCGCGTGTGGGTCTCTGGGCACAGTGGGCCTGTGTGTGTGCCCGTGTGTGT
  GTATGTGTGTGTGTATGTTTCTTAGCCCCTTGGATTCCTGCACGAAGTGGCTGATGGGAACCATTTCAAG
  ACAGATTGTGAAGATTGATAGAAAATCCTTCAGCTAAAGTAACAGAGCATCAAAAACATCACTCCCTCTC
  CCTCCCTAACAGTGAAAAGAGAGAAGGGAGACTCTATTTAAGATTCCCAAACCTAATGATCATCTGAATC
  CCGGGCTAAGAATGCAGACTTTTCAGACTGACCCCAGAAATTCTGGCCCAGCCAATCTAGAGGCAAGCCT
  GGCCATCTGTATTTTTTTTTTTCCAAGACAGAGTCTTGCTCTGTTGCCCAAGCTGGAGTGAAGTGGTACA
  ATCTGGCTCACTGCAGCCTCCGCCTCCCGGGTTCAAGCGATTCTCCCGCCTCAGCCTCCTGAGTAGCTGG
  GATTACAGGCGCGTATCACCATACCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGTTCACCATGTTGC
  CCAGGAGGGTCTCGAACTCCTGGCCTCAAGTGATCCACCGGCCTCGGCCTCCCAAAGTGCTGGGATGACA
  GGCATGAATCACTGTGCTCAGCCACCATCTGGAGTTTTAAAAGGCTCCCATGTGAGTCCCTGTGATGGCC
  AGGCCAGGGGACCCCTGCCAGTTCTCTGTGGAAGCAAGGCTGGGGTCTTGGGTTCCTGTATGGTGGAAGC
  TGGGTGAGCCAAGGACAGGGCTGGCTCCTCTGCCCCCGCTGACGCTTCCCTTGCCGTTGGCTTTGGATGT
  CTTTGCTGCAGTCTTCTCTCTGGCTCAGGTGTGGGTGGGAGGGGCCCACAGGAAGCTCAGCCTTCTCCTC
  CCAAGGTTTGAGTCCCTCCAAAGGGCAGTGGGTGGAGGACCGGGAGCTTTGGGTGACCAGCCACTCAAAG
  GAACTTTCTGGTCCCTTCAGTATCTTCAAGGTTTGGAAACTGCAAATGTCCCCTTGATGGGGAATCCGTG
  TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTTCTCCTAGACCCGTGACCTGAGA
  TGTGTGATTTTTAGTCATTAAATGGAAGTGTCTGCCAGCT
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_004878.4
• Summary: The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq, Jul 2008]
• Locus ID: 9536