PXR (NR1I2) (NM_033013) Human 3' UTR Clone

CAT#: SC213812

3`UTR clone of nuclear receptor subfamily 1 group I member 2 (NR1I2) transcript variant 3 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: NR1I2
• Synonyms: BXR; ONR1; PAR; PAR1; PAR2; PARq; PRR; PXR; SAR; SXR
• ACCN: NM_033013
• Insert Size: 1274
• Sequence Data:
  Insert Sequence

  >SC213812 3'UTR clone of NM_033013
  The sequence shown below is from the reference sequence of NM_033013. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  CAGGAGTTGTTCGGCATCACAGGTAGCTGAGCGGCTGCCCTTGGGTGACACCTCCGAGAGGCAGCCAGAC
  CCAGAGCCCTCTGAGCCGCCACTCCCGGGCCAAGACAGATGGACACTGCCAAGAGCCGACAATGCCCTGC
  TGGCCTGTCTCCCTAGGGAATTCCTGCTATGACAGCTGGCTAGCATTCCTCAGGAAGGACATGGGTGCCC
  CCCACCCCCAGTTCAGTCTGTAGGGAGTGAAGCCACAGACTCTTACGTGGAGAGTGCACTGACCTGTAGG
  TCAGGACCATCAGAGAGGCAAGGTTGCCCTTTCCTTTTAAAAGGCCCTGTGGTCTGGGGAGAAATCCCTC
  AGATCCCACTAAAGTGTCAAGGTGTGGAAGGGACCAAGCGACCAAGGATGGGCCATCTGGGGTCTATGCC
  CACATACCCACGTTTGTTCGCTTCCTGAGTCTTTTCATTGCTACCTCTAATAGTCCTGTCTCCCACTTCC
  CACTCGTTCCCCTCCTCTTCCGAGCTGCTTTGTGGGCTCCAGGCCTGTACTCATCGGCAGGCGCATGAGT
  ATCTGTGGGAGTCCTCTAGAGAGATGAGAAGCCAGGAGGCCTGCACCAAATGTCAGAAGCTTGGCATGAC
  CTCATTCCGGCCACATCATTCTGTGTCTCTGCATCCATTTGAACACATTATTAAGCACCGATAATAGGTA
  GCCTGCTGTGGGGTATACAGCATTGACTCAGATATAGATCCTGAGCTCACAGAGTTTATAGTTAAAAAAA
  CAAACAGAAACACAAACAATTTGGATCAAAAGGAGAAATGATAAGTGACAAAAGCAGCACAAGGAATTTC
  CCTGTGTGGATGCTGAGCTGTGATGGCGGGCACTGGGTACCCAAGTGAAGGTTCCCGAGGACATGAGTCT
  GTAGGAGCAAGGGCACAAACTGCAGCTGTGAGTGCGTGTGTGTGATTTGGTGTAGGTAGGTCTGTTTGCC
  ACTTGATGGGGCCTGGGTTTGTTCCTGGGGCTGGAATGCTGGGTATGCTCTGTGACAAGGCTACGCTGAC
  AATCAGTTAAACACACCGGAGAAGAACCATTTACATGCACCTTATATTTCTGTGTACACATCTATTCTCA
  AAGCTAAAGGGTATGAAAGTGCCTGCCTTGTTTATAGCCACTTGTGAGTAAAAATTTTTTTGCATTTTCA
  CAAATTATACTTTATATAAGGCATTCCACACCTAAGAACTAGTTTTGGGAAATGTAGCCCTGGGTTTAAT
  GTCAAATCAAGGCA
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_033013.2
• Summary: This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. [provided by RefSeq, Jul 2008]
• Locus ID: 8856