BPNT1 (NM_006085) Human 3' UTR Clone

CAT#: SC214152

3`UTR clone of 3'(2') 5'-bisphosphate nucleotidase 1 (BPNT1) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: BPNT1
• Synonyms: HEL20; PIP
• ACCN: NM_006085
• Insert Size: 1378
• Sequence Data:
  Insert Sequence

  >SC214152 3'UTR clone of NM_006085
  The sequence shown below is from the reference sequence of NM_006085. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  CAAGCCGAGTTCCAGAATCTATTAAAAATGCACTTGTTCCTTAAAGGAAAGTTTCATTTGGCCGGGCGCG
  GTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACTTGAGCTCAGGAGTTTG
  AGACCAGCCTGGGCAATATCGTGAGACCCCATCTCTACAAAAATACAAATTAACTGGGCATCCTGTCATG
  CGCCTGTCATCCCAGCTACTTGAGAGGCTGAAGCAGAAGAATCTCTTGAGCCCGGAAGGCAGAGGTTGCA
  GTGAGCTGAGATCGTGCCACTGCACTCCAGCCTGAGTGACAGGAGTTAAGCCCTGTCTCAGAAAAAAAAA
  AAACAAAAACCCAAAAAGTACTTAAAGTTTCATTTACTTAGCTAGGAGAAAGACTTGGTTCTCAAAATAA
  TACATTTTAAGATTAATTGGGTAGAATTAGAGTTCCACCTTTATTCATTGTTGAGCAGTGATTTATATTT
  AGTTATTATATTTAGGAATAGAAAATAGAATTAAATAATTTAACTTGATTAATCAACCAGACCAATTTTG
  ACGTCTGGAGAACTTATAAACTCAATATGTTATATTTGTTTTCCTGTATTTAGGTGGAGAAATGAGAAAA
  AGCTTTAGTTCCAATTGACAGTTCAGGTCAATGTTCAATGAACATTCCTATCTTCTAAACCAGATTTCTC
  TTTTTTTTTCCTGAGACGGAGTCTCGCTCTGTAGCCTAGGCTAGAATGTAGTGGCGTGATCTCGGCTCAC
  TGCAAGCTCCGCCTCCCGGGTTCATGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTGCAGGCA
  CCGCCACCACGCCTGGCTAATTTTTTGTATTTTTAGTAGAGAAGGTGTTTCACCGTGTTAGCCAGGATGG
  TCTTGATCTCCTGACATCGTGATCTGTCTGCCTCGGACTCCCAAAGTGCTGGGATTACAGGTGTGAGCCA
  CCGCACCTGGCCTAAACCAGATTTCTTTAGGGCACAATTTTTTCTGGAATCTCACTCTTGTTTTTCACAG
  TAATTTTAAAAACGTTTCTACTCCAATTAAGAATATATATGATGTTATTATATATGCTTATGAAACAGAT
  TTATGAGAAAAGTTTTTTTTAAATAAATTATTTAATCCTAGCTCTTTGTTATTCACCAGCTTTTTAAAAA
  AGTGTTTGAAAATTATACATTCTCGACTTTGGGGATTAGTTTATTCTTGTGGCATCATTATAAGGCTTAA
  TTGTGGAAAGCTAAGTACTTGCTTCTATTCCTTCCAATGAGAGATTATAACATAAACTATTAAAATTATT
  CTGCTAATATACCTAGATTTTTATTTTTAGGTCTCTGTCCATTGCTTT
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_006085.4
• Summary: BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity. [provided by RefSeq, Jul 2008]
• Locus ID: 10380