PAK6 (NM_020168) Human 3' UTR Clone

CAT#: SC214664

3`UTR clone of p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6) transcript variant 1 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: PAK6
• Synonyms: PAK5
• ACCN: NM_020168
• Insert Size: 1395
• Sequence Data:
  Insert Sequence

  >SC214664 3'UTR clone of NM_020168
  The sequence shown below is from the reference sequence of NM_020168. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  CTCTACCGAAAGCAGACCTCCACCTGCTGAGCCCACCCCAAGTATGCCTGCCACCTACGCCCACAGGCAG
  GGCACACTGGGCAGCCAGCCTGCCGGCAGGACTTGCCTGCCTCCTCCTCTCAGTATTCTCTCCAAAGATT
  GAAATGTGAAGCCCCAGCCCCACCCTCTGCCCTTCAGCCTACTGGGCCAGGCCGGACCTGCCCCCTCAGT
  GTCTCTCCCTCCCGAGTCCCCAGATGGAGACCCCTTTCTACAGGATGACCCCTTGATATTTGCACAGGGA
  TATTTCTAAGAAACGCAGAGGCCAGCGTTCCTGGCCTCTGCAGCCAACACAGTAGAAAAGGCTGCTGTGG
  TTTTTTAAAGGCAGTTGTCCACTAGTGTCCTAGGCCACTGCAGAGGGCAGACTGCTGGTCTCCACAGATA
  CCTGCTGTTCTCAGCTCCAGCTTCAAACCTCGAGTCTCGAGAGGGCCACGGGGTGGTTTTTATGACCGGA
  ATCCCGCTTCCTCCCTCACGTCTGATGTCCTGAAGGTGCAGTCCCACCTGTACAGCCCCTCCCCGCCCAG
  AACTGTGAATGGCCTGCTCCAGGCCATGGCTGGGGGCAGGGAGTGAGGGGACAATTTCTGAGTGAAAGAG
  AAAGAATGGGGTCGGTGGTGAAGGTGCTCTCACTTTACAGAATGGAGAGAACATCGTGTGTGTGTGTGTG
  TGTGTGTGTGTGTGTGTGTGTGTGTAAGGGGAGGAAAGCCACCTTGACAGCCCAGGTCCCTCCAGGTCAC
  CCACAGCCAGTTTCAGGAAGGCTGCCCCTCTCTCCCACTAAGTTCTGGCCTGAAGGGACCTGCTTTCTTG
  GCCTGGCTTCCACCTCTCCACTCCTGTGTCTACCTGGCCAGTGGAGTGGTCCATGCTAAGTCTAACACTC
  CTGGGAGCTCAGGAGGCTTCTGAGCTTCTCCTGTACTGTGCATCGTGAGGGCCAGAGACAGGAATGTAAG
  GATTGGCAACTGTGTTACCTTTCAAGTTTATCTCAATAACCAGGTCATCAGGGACCCATTGTTCTCTTCA
  GAACCCTATCTGGGAGAGAAGGCGAACCACCTCCGGGTTTCCATCATGTCAAGGTCACAGGCATCCATGT
  GTGCAAACCATCTGCCCCAGCTGCCTCCACAGACTGCTGTCTCCTTGTCCTCCTCGGCCCTGCCCCACTT
  CAGGGCTGCTGTGAGATGGAATTCCAGGAAAGAACTTCAGGTGTCTGGACCCTTTCTATCTAGATAATAT
  TTTTAGATTCTTCTGCTCCCTAGTGACCTACCTGGGGGCAAAGAAATTGCAAGGACTTTTTTTTAAGGGT
  CAGAGTTTTCAAAACAAAAGCATCTTCCCTAGAAATTTTTGTGAATTGTTTGCACTTGTGCCTGT
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_020168.4
• Summary: This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
• Locus ID: 56924