IL21 Receptor (IL21R) (NM_021798) Human 3' UTR Clone

CAT#: SC215002

3`UTR clone of interleukin 21 receptor (IL21R) transcript variant 1 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: IL21R
• Synonyms: CD360; IMD56; NILR
• ACCN: NM_021798
• Insert Size: 1536
• Sequence Data:
  Insert Sequence

  >SC215002 3'UTR clone of NM_021798
  The sequence shown below is from the reference sequence of NM_021798. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  GTCATTCCTCCGCCACTTTCGAGCCCTGGACCCCAGGCCAGCTAATGAGGCTGACTGGATGTCCAGAGCT
  GGCCAGGCCACTGGGCCCTGAGCCAGAGACAAGGTCACCTGGGCTGTGATGTGAAGACACCTGCAGCCTT
  TGGTCTCCTGGATGGGCCTTTGAGCCTGATGTTTACAGTGTCTGTGTGTGTGTGTGCATATGTGTGTGTG
  TGCATATGCATGTGTGTGTGTGTGTGTGTCTTAGGTGCGCAGTGGCATGTCCACGTGTGTGTGTGATTGC
  ACGTGCCTGTGGGCCTGGGATAATGCCCATGGTACTCCATGCATTCACCTGCCCTGTGCATGTCTGGACT
  CACGGAGCTCACCCATGTGCACAAGTGTGCACAGTAAACGTGTTTGTGGTCAACAGATGACAACAGCCGT
  CCTCCCTCCTAGGGTCTTGTGTTGCAAGTTGGTCCACAGCATCTCCGGGGCTTTGTGGGATCAGGGCATT
  GCCTGTGACTGAGGCGGAGCCCAGCCCTCCAGCGTCTGCCTCCAGGAGCTGCAAGAAGTCCATATTGTTC
  CTTATCACCTGCCAACAGGAAGCGAAAGGGGATGGAGTGAGCCCATGGTGACCTCGGGAATGGCAATTTT
  TTGGGCGGCCCCTGGACGAAGGTCTGAATCCCGACTCTGATACCTTCTGGCTGTGCTACCTGAGCCAAGT
  CGCCTCCCCTCTCTGGGCTAGAGTTTCCTTATCCAGACAGTGGGGAAGGCATGACACACCTGGGGGAAAT
  TGGCGATGTCACCCGTGTACGGTACGCAGCCCAGAGCAGACCCTCAATAAACGTCAGCTTCCTTCCTTCT
  GCGGCCAGAGCCGAGGCGGGCGGGGGTGAGAACATCAATCGTCAGCGACAGCCTGGGCACCCGCGGGGCC
  GTCCCGCCTGCAGAGGGCCACTCGGGGGGGTTTCCAGGCTTAAAATCAGTCCGTTTCGTCTCTTGGAAAC
  AGCTCCCCACCAACCAAGATTTCTTTTTCTAACTTCTGCTACTAAGTTTTTAAAAATTCCCTTTATGCAC
  CCAAGAGATATTTATTAAACACCAATTACGTAGCAGGCCATGGCTCATGGGACCCACCCCCCGTGGCACT
  CATGGAGGGGGCTGCAGGTTGGAACTATGCAGTGTGCTCCGGCCACACATCCTGCTGGGCCCCCTACCCT
  GCCCCAATTCAATCCTGCCAATAAATCCTGTCTTATTTGTTCATCCTGGAGAATTGAAGGGAGGTCAAGT
  TGTTTGTCAATGATTTGTCAGAGAACCTGTTGAAATGTGAATTAAGAAGCTAAGAAAATATTTCTTAGCA
  ACATTTTCTTTTTCTTTTTTTTTTTTTTCTTTTGAGACAGAGTCTCACTCTCGTCGCCCAGGCTGGAATG
  CAGTGGTGCGATCTCGGCTCTCTGCAACCTCTGTCTCCCGGGTTCAAGCGATTTCCTGCGTCAGCCCCAG
  AGTAGCTGGAATTACAGGCACACACCACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGCTGGG
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_021798.2
• Summary: The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
• Locus ID: 50615