IL21 Receptor (IL21R) (NM_181078) Human 3' UTR Clone
CAT#: SC215003
3`UTR clone of interleukin 21 receptor (IL21R) transcript variant 2 for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | IL21R |
Synonyms | CD360; IMD56; NILR |
ACCN | NM_181078 |
Insert Size | 1536 |
Sequence Data |
>SC215003 3'UTR clone of NM_181078
The sequence shown below is from the reference sequence of NM_181078. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC GTCATTCCTCCGCCACTTTCGAGCCCTGGACCCCAGGCCAGCTAATGAGGCTGACTGGATGTCCAGAGCT GGCCAGGCCACTGGGCCCTGAGCCAGAGACAAGGTCACCTGGGCTGTGATGTGAAGACACCTGCAGCCTT TGGTCTCCTGGATGGGCCTTTGAGCCTGATGTTTACAGTGTCTGTGTGTGTGTGTGCATATGTGTGTGTG TGCATATGCATGTGTGTGTGTGTGTGTGTCTTAGGTGCGCAGTGGCATGTCCACGTGTGTGTGTGATTGC ACGTGCCTGTGGGCCTGGGATAATGCCCATGGTACTCCATGCATTCACCTGCCCTGTGCATGTCTGGACT CACGGAGCTCACCCATGTGCACAAGTGTGCACAGTAAACGTGTTTGTGGTCAACAGATGACAACAGCCGT CCTCCCTCCTAGGGTCTTGTGTTGCAAGTTGGTCCACAGCATCTCCGGGGCTTTGTGGGATCAGGGCATT GCCTGTGACTGAGGCGGAGCCCAGCCCTCCAGCGTCTGCCTCCAGGAGCTGCAAGAAGTCCATATTGTTC CTTATCACCTGCCAACAGGAAGCGAAAGGGGATGGAGTGAGCCCATGGTGACCTCGGGAATGGCAATTTT TTGGGCGGCCCCTGGACGAAGGTCTGAATCCCGACTCTGATACCTTCTGGCTGTGCTACCTGAGCCAAGT CGCCTCCCCTCTCTGGGCTAGAGTTTCCTTATCCAGACAGTGGGGAAGGCATGACACACCTGGGGGAAAT TGGCGATGTCACCCGTGTACGGTACGCAGCCCAGAGCAGACCCTCAATAAACGTCAGCTTCCTTCCTTCT GCGGCCAGAGCCGAGGCGGGCGGGGGTGAGAACATCAATCGTCAGCGACAGCCTGGGCACCCGCGGGGCC GTCCCGCCTGCAGAGGGCCACTCGGGGGGGTTTCCAGGCTTAAAATCAGTCCGTTTCGTCTCTTGGAAAC AGCTCCCCACCAACCAAGATTTCTTTTTCTAACTTCTGCTACTAAGTTTTTAAAAATTCCCTTTATGCAC CCAAGAGATATTTATTAAACACCAATTACGTAGCAGGCCATGGCTCATGGGACCCACCCCCCGTGGCACT CATGGAGGGGGCTGCAGGTTGGAACTATGCAGTGTGCTCCGGCCACACATCCTGCTGGGCCCCCTACCCT GCCCCAATTCAATCCTGCCAATAAATCCTGTCTTATTTGTTCATCCTGGAGAATTGAAGGGAGGTCAAGT TGTTTGTCAATGATTTGTCAGAGAACCTGTTGAAATGTGAATTAAGAAGCTAAGAAAATATTTCTTAGCA ACATTTTCTTTTTCTTTTTTTTTTTTTTCTTTTGAGACAGAGTCTCACTCTCGTCGCCCAGGCTGGAATG CAGTGGTGCGATCTCGGCTCTCTGCAACCTCTGTCTCCCGGGTTCAAGCGATTTCCTGCGTCAGCCCCAG AGTAGCTGGAATTACAGGCACACACCACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGCTGGG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_181078.1 |
Summary | The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010] |
Locus ID | 50615 |
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