Cytochrome P450 2B6 (CYP2B6) (NM_000767) Human 3' UTR Clone

CAT#: SC215362

3`UTR clone of cytochrome P450 family 2 subfamily B polypeptide 6 (CYP2B6) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: CYP2B6
• Synonyms: CPB6; CYP2B; CYP2B7; CYP2B7P; CYPIIB6; EFVM; IIB1; P450
• ACCN: NM_000767
• Insert Size: 1595 bp
• Sequence Data:
  Insert Sequence

  >SC215362 3'UTR clone of NM_000767
  The sequence shown below is from the reference sequence of NM_000767. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  CCAACATACCAGATCCGCTTCCTGCCCCGCTGAAGGGGCTGAGGGAAGGGGGTCAAAGGATTCCAGGGTC
  ATTCAGTGTCCCCGCCTCTGTAGACAATGGCTCTGACTCCCCGCAACTTCCTGCCTCTGAGAGACCTGCT
  ACAAGCCAGCTTCCTTCCCCTCCATGGCACCAGTTGTCTGAGGTCACATTGCAAGTGAGTGCAGGAGTGA
  GATTATCGAAAATTATAATATACAAAATCATATATATATATATGTTCTTGTTTTTTGAGACAGAGTCTCA
  CACTGTTGCCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCAACCTCCACCCCCGGGGATCAAG
  CAACTCTCCTGCCTCAGCCTCCCTAGTAGCTGGGATTACAGGCATGCACTACCACGCTTGGCTAATTTTT
  GTATTTTTAGTAGAGATGGGGTTTCACTGTGTAGGCCAGGCTGGTCTCGAACTCCTGAACTCAAGTGATT
  CACCCACCTTAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGTCACCGTGCCCAGCCATGTATATATAT
  AATTTTAAAAATTAAGCTGAAATTCACATAACATAAAATTAGCTGTTTTAAAGTGTAAAATTTAGTGGCG
  TGTGGTTCATTCACAAAGCTGTACAACCACCACCATCTAGTTCCAAACATTTTCTTTTTTTCTGAGATGG
  AGTCTCACTCTGTCACCCAGGTTCGAGTTCAGTGGTGCCATCTCTGTCCACTGCAACCTCCACATCCTGG
  GTTCAAGTGATTCTCCTGCCTCAGCCTCTGGAGGAGCTGGTATCACAGGCGTCCCCCACCACGCCTGGCT
  AAATTTTGTATTTTTAGGTGGTCTTGAACTCCTGATGTCAGGTGATTCTCCTAGCTCCAAATGTTTTCAT
  TATCTCTCCCCCAACAAAACCCATACCTATCAAGCTGTCACTCCCCATACCCCATTCTCTTTTTCATCTC
  GGCCCCTGTCAATCTGGTTTTTGTCACTATGGACTTACCAATTCTGAATATTTCCCATAAACAGAATCAT
  ACAATATTTGATTTTTTTTTTTTTTTTGAAACTAAGCCTTGCTCTGTCTCCCAGGCTGGAGTGCTATGGT
  GCAATTTTTGTTCACTGCAACCTCTGCCTTCCAAGATCAAGAGATTCTCCAGTCTCAGCTCCCAAGTAGC
  TGGGATTACAGGCATGTACTACCATGCCTGGCTAATTTTCTTGTAGTTTTAGTAGGGACATGTTGGCCAG
  GCTGGTGGTGAGCTCCTGGCCTCAGGTGATCCACCCACCTCAGTGTTCCAAAGTGCTGATATTACAGGCA
  TAATATGTGATCTTTTGTGTCTGGTTGCTTTCATGTTGAATGCTATTTTTGAGGTTCATGCCTGTTGTAG
  ACCACAGTCACACACTGCTGTAGTCTTCCCCAGTCCTCATTCCCAGCTGCCTCTTCCTACTGCTTCCGTC
  TATCAAAAAGCCCCCTTGGCCCAGGTTCCCTGAGCTGTGGGATTCTGCACTGGTGCTTTGGATTCCCTGA
  TATGTTCCTTCAAATCTGCTGAGAATTAAATAAACATCTCTAAAGCCTGACCTCC
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

• RefSeq: NM_000767.4
• Summary: 'This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008]'
• Locus ID: 1555