SNAP23 (NM_130798) Human 3' UTR Clone
CAT#: SC215438
3`UTR clone of synaptosomal-associated protein 23kDa (SNAP23) transcript variant 2 for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | SNAP23 |
Synonyms | HsT17016; SNAP-23; SNAP23A; SNAP23B |
ACCN | NM_130798 |
Insert Size | 1589 |
Sequence Data |
>SC215438 3'UTR clone of NM_130798
The sequence shown below is from the reference sequence of NM_130798. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC GCCAATGCCAGAGCAAAGAAACTCATTGACAGCTAAAGCTACTGCTGTTCTTCTTTATCATTTATTCACT TCCGTAGCTCCTCCTTGAAAGTTATTACCTTTTCAGAGTTTAAGTTTTCGGTTCCACGCTCTTCTAATTG GGAGATAATATGGAAGAAGGGCCAGAGCAGTTACAGCCCTCCTTCTTTTTTGTTTTCTGTTGAGGGCCGA CTGCTGCTCTGCCTTCCTTCTAGTATTTTCTTTCTCAATTCATACGCTTAGATTGGTTTTCATATGTCAT GTTTAGTGTTTTCATCCTCCTCATATACTTCAGCAGGTTCTTTTGCTTTCAAGATTTGGAAGCATTGCCA AAGACAGCCATGAAGAAGGAAGCTGTAGAGGTGTTTTTTGTTGTTGTTTATTTTTGCTTTTGTGGTTGAG GGAAGGACAAGAGATAAGAGGTTGTTACCTCAGTAAAAACCTTCAGGCCACAAAGCAAAAAGTTGCATAG CCACAACGAAGATCTAGTTGGATATAGTTTTTGATTTAAGTTGCAGTTATAGCCAATTTAGGCTAATGCT TGGTTTTGGAGCTTTTATACACAACGTTTTTGTTAGGCATCACAGTTTTGCAACCTCTGCTCCAAAGAGA AAAATAGAATGAGTTTTCTTTCTTTTTTTTTTTTTTGGAGTCAGAGTCTCGCTCTCTTGTCCAGGCTGGA GTGCAATAGCGCGATCTGGGCTCACTGCAACCTCCGCCTCCCTGGTTCAAGCAATTCTCCTGCCTTGCCT CCTGAGTAGCTGGGATTACAGGCGTGTGTCACCACGCTCGGCTAATTTTTGTATTTTTAGTAGAGACAGG GTTTCACCATGTCAAGCTGGTCTTGGACTCCTGACGTCGTGATCCACCCGCCTTGGCCTCCCAAAGTACT GGGATTACAGGCGTGAGCCACTGTGCCTGGCTGAGTTTTCTTAAAGTGAGCTTAATTTCTGAACTCTTAG TGATTCATATATGTACATAAATCTGTGATCCCATTTCTTATTGCACCATTCAGGAACACTTTATATAAAT GAGTGGCTTTTTATTTCATATTATTAGTAGTATCATGGTTCCATTACAGGCCTATTAACATCATACATTG TCATTAGTCTTTGAAGAAAAAATATGTAAATATATATGTGTAACATGAGAATTTCTCTCTAAAGCAGGGC TTAAAATTTTTTGGAAAAGTTTGACAAAGCATACCACATGAATTCAGATTTACCTCAATGCTAAGAATTA TGTTTAGTTAGGAAAAAGGAAAGTCATTTTGACCTCAGGTAGAAAAATAGATTGCTTTGAGTTTTATGTA GCTTTAGACTTTAAAAAGTTAGAATTTATTCTGTAACTAAAAATTATTTGAAAAAATTATGCCTCTGGTT TAATTATTGGTGATTACACACTCTTTCTCTTACCCTTGTGTATTGAACTATGTCCATAATCAAGTTGATG TGGATCCTGAAAAGTGTTATGAACATCTGATTGGTATTTGTCACATTTATTTTAAAATTAGCATCTGAAC ACTTCAAAGCTGTCAGTGTGTATTGGTTTCACCAATAACCACTGCTTGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_130798.1 |
Summary | Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
Locus ID | 8773 |
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