PTPN7 (NM_080588) Human 3' UTR Clone

CAT#: SC215494

3`UTR clone of protein tyrosine phosphatase non-receptor type 7 (PTPN7) transcript variant 2 for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: PTPN7
• Synonyms: BPTP-4; HEPTP; LC-PTP; LPTP; PTPNI
• ACCN: NM_080588
• Insert Size: 1589
• Sequence Data:
  Insert Sequence

  >SC215494 3'UTR clone of NM_080588
  The sequence shown below is from the reference sequence of NM_080588. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  AGCTGCCTGAGGAACCCAGCCCCTGACCCCTGCCACCCTCCGGTGGCCCAGGTGCCTACCTCCCTCAAGC
  CTGGGAAGGTGGGTCTGGGGAAAGTGGGCCGAGTGATCTGGGGGTACCCCTTGGGTTGGTGTGGGGAAGG
  AGTGCCTCCTTAGTGGTGCTTGCAGTCACAGGAAGCAGCAGCAGTAAGGACAAGGGGCCGGATTCCAGGT
  CTTCAACACTGGCCACTCCTCTGCTTCCTCTGTTGGCCCCAGATGGACAGTAAGGGGAACCTCCAATGTC
  TCTCTGAACTTAAAGACAGGAGCTGGCATTTATGACAGACAAAGAAAGAAGCCCAGGTGTCCTGGTGTTC
  TCTGAGACACTCTTTGTGAGCTTCAGTTTCCTGTTCTATAACATGAACATAAGTGCTTAGCTGCCATGAG
  GGAAAAGTAATGAGAGAAGTTTCTAGAAGCCACTCCAGCCACTCCTTCCTGGGGCTGACAAAAGGGTGAT
  TCCAAGATCATCCTTCACCCGAGGTCCTGCCCAAGCACAGGCCAGATGCAAGAATGGGGAAAAGTCTGGT
  CCTGATCTCCAAGTCTCAACATCCTATCAGTGACTCTGCTCCCTGACCACACATCGGAAGGGCTGGATGA
  CCCCAATCAAAAGAAAGAACAAGGACTCTGGTTACCCTTGCCTCCACCCATGTGTCATAAGAGTAGGCTA
  CAGAGGTGACCAGGCCTGGCAGTTGAAATCTCTGGAAGAGGGAACATGTGGGGACTACTCAGAGGCAAAG
  AGGAGCTGCTCCTGCCTCCATGGTTGCTGGCCACTCCCACCAACTACTCTTAGGGAGGCTAAGCAGTCTC
  TGTTTTGCTTCCATGGCTCAAATAATACCCTGGGTATGCAGGACCCACTATACCTTGCATTTGCTGAGTA
  CACCTAGAGAGCTTGGCTGTTTCCAAAAACAATCAGGGTCATAACCATCCATGCAGACATGGAGGCTCGG
  CTGAACCAGGACTCCTCACTGTCTACCTGAGAGAATGAGCACCCCTCATCCATCTCAGCATCAACACAAT
  TTCCAGGGGACCTCAGGTCTACCTCAGGACTGAACGCCACACCTCAGGATTCCTCCTCCTTGAATCTGAG
  ACTGGCTGCCCATTCTGAGATGGGGATGAAGGTAAGATGCCGCATCACCAGGCACGCCGCCCCTGACAGC
  TGCCTTGATACCAGCTCTCTGTGGAAACCCCCGAGGAGTTGGATCTGGAGAACAGCTGGGCCTCCTCACT
  CAGGACTTCTCTCCTGAAGAACACGCAGTGCTAAAACTGAGGATGATTTCCCTAATGCTTCTGCTTGGCC
  TTATGGAGGAGCTGCTCCTTCCTTACAGCCTTGGGGATGGACTTGCCCACACCTCCACCTCCCCTGAGCC
  CTGTGAGAGGCACGACTGTCTATGCCAATGAGGCTCGGTGGGGGGCTCTCAAGTGCCTGATCCTGCCCTG
  GGCTCAGAGCCAGCCCAGAGGGAAGCAACTGCACAGCCCCACAGGCCCTCCCTGGCACTGTCCCCCCAAC
  CCCATCTCAGAGCTCAGAGGGTACAAGCTCCAGAACAGTAACCAAGTGG
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_080588.1
• Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2010]
• Locus ID: 5778