LOX 1 (OLR1) (NM_002543) Human 3' UTR Clone

CAT#: SC215522

3`UTR clone of oxidized low density lipoprotein (lectin-like) receptor 1 (OLR1) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: OLR1
• Synonyms: CLEC8A; LOX1; LOXIN; SCARE1; SLOX1
• ACCN: NM_002543
• Insert Size: 1597 bp
• Sequence Data:
  Insert Sequence

  >SC215522 3'UTR clone of NM_002543
  The sequence shown below is from the reference sequence of NM_002543. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  GGCAAACCTAAGAGCACAGTGAATTTGAAGGCTCTGGAAGAAAAGAAAAAAGTCTTTGAGTTTTATTCTG
  GAATTTAAGCTATTCTTTGTCACTTGGGTGCCAAACATGAGAGCCCAGAAAACTGTCATTTAGCTGGCTG
  CAGAACTCCTTTGCAGAAACTGGGGTTCCAGGTGCCTGGCACCTTTATGTCAACATTTTTGATTCTAGCT
  ACCTGTATTATTTCACCTAGCTTGTCCCAAGCTTCCCTGCCAGCCTGAAGTCCATTTTCCCCTTTTTATT
  TTAAAATTTGACTCCTCTTCAAGCTTGAAAACCCTCTGAACTCAGTCTTCTTTACCTCATTATCACCTTC
  CCCTCACACTCCTAAAATTGCATGAAAGACAGAACATGGAGAACTTGCTCAAGTGCAGGCAGAGAGCAAA
  AAGGGGAAATATGTCTGGGAAAAAGTGCACGTGAAGAAACAAAGAAGGACAGAGGCCATTCCGAAATCAA
  GAAACTCATGTTCTTAACTTTAAAAAAGGTATCAATCCTTGGTTTTTAAACTGTGGTCCATCTCCAGACT
  CTACCACTTACGGACAGACAGACAGACAGACACACACACACACACACACACACATTTTGGGACAAGTGGG
  GAGCCCAAGAAAGTAATTAGTAAGTGAGTGGTCTTTTCTGTAAGCTAATCCACAACCTGTTACCACTTCC
  TGAATCAGTTATTATTTCTTCATTTTTTTTTCTACCAGAGGACAGATTAATAGATTTAACCCTTCACAAC
  AGTTCTTGTTAGAATCATGGGATGTGTGGCCCAGAGGTAAGAATAGAATTTCTTTCCCTAAAGAACATAC
  CTTTTGTAGATGAACTCTTCTCAACTCTGTTTTGCTATGCTATAATTCCGAAACATACAAGACAAAAAAA
  ATGAAGACACTCAATCTAGAACAAACTAAGCCAGGTATGCAAATATCGCTGAATAGAAACAGATGGAATT
  AGAAATATATCTTCTATTTTTAGGCTTCTATTTCCTTTCCACCCACTCTTCACAGGCTATTCTACTTTAA
  AGGAAGCCTTTTTATTTTGCTGCACACAATCTAGCAGGAATCTTTTTTTTTTTTTAAGAGCTGTGTCATC
  CTTATGTAGGCAAGAGATGTTTGCTTTTGTTAAAAGCTTTATTGAGATATAATTAACATAAAATAAACTG
  AACATATTTAAAGTGTACTATTTGATAAGTTTTCACACCTTGTGGAGAACATGCATACTACAATTAAGAG
  AGTGAACATATCCATCATCCCTCAAAGTGTCACAATGCTCCTCCTGATGACTCCTCCCCAGAAAACCACC
  AATCGGCTTTCATTTTGCATTTTGTAGTTTTATGTGAATGGAATCATATAGTATGTCTTTTTTTTTTGTC
  TGGCTTCTTTCACTTTGCATAATTATTTTGAGATTCATATGTCTCCATCTTGATGCTCGTATGAATTCAT
  TCTTTTAAATGTTGAATATTCCCTTGTATGGATATACCACAATTCATTTACCCATTTACTTGTTGATGAC
  ATTTGGGTTGTTTTAGTTTTGGGATATTACAAATAAAGCTGCTGTGAACATTTGTGT
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

• RefSeq: NM_002543.3
• Summary: 'This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]'
• Locus ID: 4973