BCL10 (NM_003921) Human 3' UTR Clone

CAT#: SC216787

3`UTR clone of B-cell CLL/lymphoma 10 (BCL10) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: BCL10
• Synonyms: c-E10; CARMEN; CIPER; CLAP; IMD37; mE10
• ACCN: NM_003921
• Insert Size: 1849
• Sequence Data:
  Insert Sequence

  >SC216787 3'UTR clone of NM_003921
  The sequence shown below is from the reference sequence of NM_003921. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon
  
  
  CAATTGGCAGAGCTCAGAATTCAAGCGATCGC
  
  CGTACTGTTTCACGACAATGACACTTTATTGCCTTTTAATTTTTAATGATGACAAAAAATGTTTTAAAGA
  ATATGACTTTTTATAAAATGGCTGTAATCATTTGTTTACATTTGATGCATGTCTTTTAAAATGCAATGTA
  AGCATACTTTGTAAATAGGATTTTTAGAATTAAAAAAGCATACTTCTAGGATAGCTAACTGTAAATCATG
  TTGATCATGTACTTTTTAGTAATTTCTTTTTTTCCTTTTTAAGGTCTTTCAGTACTTTTTTAAATATTTT
  CTATTTTAAGACTGATTTTAATAGGGAATATATCTCTATTTGAGAATAGACCCTTACTAGGAAGAACGTT
  TTTTCCTCAGTGCATTTGTGCTAGAAATTTTCAAGAGTCTAATAGTCTTTGCCAGTCATTCAGCAGCAAA
  TTTTCAGCATTAAGCTGTTCCTGTTCAGTAATAAAACCGGTCACTGATGGGAAAACTGCCAATATAGAAA
  AATAAAAATCTCTTTTCCACTCCATTGTCGTATAGGCATGTAAACAGCCTCTTTTTGATACTGGAGGAAC
  ACTTGATGGAGTGTGAGCCACCTAAGATCTCGGTTTGCCAAAATTCATTTCTAATTAACCTTACTAATTA
  TACTACTTTGTTAGGATTTTCACATTCTTGGCTTAATCATTTTCATTCCTAAAGAAAAATATCTTGGCCT
  AAACCTCAGTTATTACATGTAATTTGATGAGGTATTTTTTCCTTTTTTCTTTTTTTTTTTTTTTTTTTTT
  TGAGACAGTCTTGCTCTATCGCCCAGGCTGGAGTGCAGTGGCGCATTCTAGGCTCACTGCAACTTCTGCC
  TCCCATGCTTACGTGATCCTCTCACCTCAGCCTCTCAAGTAATATAGCTGAGACTACAAGTGTGTGCCAC
  CATGCCTCACTAATTTTTGTATTATTTTTGTAGAGACGGTGTTTTGCCATGTTGGCCAGGCTGGTCTTGA
  ACTCCTGGACTCAAGCAACCTACCCAGCGTGGCCTCCCAAAGTGCTGGGATTACAGACACGAGCCACCTC
  ACCTAGCCTGATGAGATTTTTAAAAAATATTTTCTCTGTACTTTTCATTCTCTTTTAATGAGGACCAATG
  TACAGTTGAAATAACTGGAACAAATTATTTTTGGTGTGTGTGACAATTCTGTTTTTAATGCTATTTGAAC
  AAGTGGGCCATTAGCCAGATTTGTCTTTTTGTTGTAAAACAAAATTTGACTAATTTTACATGTTTATAAA
  TCTTATGCTCTCACTGTTTGTTTTTATTTAAATTACAATTTTATCTGTTTCCTGACATTGTCTCCTATAT
  ATTTCTATTATTAATTGCAAAAACATAGAAATGGAAATTTTGCTATCAACAATAAAATTTTTTTAAAGTA
  GTGAGTGCTATTTTGGAGTTCCAAATTTTCAGTAGGAAGTATCTAAAACTTTTTTTAATACGTGCCATTA
  TCTATAGAAAACATTACTTCAGGTTGTGAGATTGAGTTGCATTTCTGGATGGACTGATGAATTTATCCGA
  CATGAAGAAGATTGGCATATTAGCTTTAAAAATTTTTAAAGATTGGATTTTTTTTAGTATAAGCACTTTC
  TAAGGATTATAGAGAAATGTTTCACCTCCAATGCATAGCAAAAATAGTGGTGTTAGAAAGAAAATAGGTT
  ACATTTAAGGAAGGTGCTTTAAAAAGCAGAAGCAGACTTTAAAATTAAATTTGTGGACACCTTTTTAAAA
  ATTGAATCAAAGATTATAATTTAGATATACAATAACACCTATATATAGATAAGTTTTAACACTGAGTTTT
  CTTTCAGACTGTTTTCTAACTACATAGAC
  
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).

Reference Data

• RefSeq: NM_003921.4
• Summary: This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
• Locus ID: 8915