BCL10 (NM_003921) Human 3' UTR Clone
CAT#: SC216787
3`UTR clone of B-cell CLL/lymphoma 10 (BCL10) for miRNA target validation
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Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | BCL10 |
Synonyms | c-E10; CARMEN; CIPER; CLAP; IMD37; mE10 |
ACCN | NM_003921 |
Insert Size | 1849 |
Sequence Data |
>SC216787 3'UTR clone of NM_003921
The sequence shown below is from the reference sequence of NM_003921. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC CGTACTGTTTCACGACAATGACACTTTATTGCCTTTTAATTTTTAATGATGACAAAAAATGTTTTAAAGA ATATGACTTTTTATAAAATGGCTGTAATCATTTGTTTACATTTGATGCATGTCTTTTAAAATGCAATGTA AGCATACTTTGTAAATAGGATTTTTAGAATTAAAAAAGCATACTTCTAGGATAGCTAACTGTAAATCATG TTGATCATGTACTTTTTAGTAATTTCTTTTTTTCCTTTTTAAGGTCTTTCAGTACTTTTTTAAATATTTT CTATTTTAAGACTGATTTTAATAGGGAATATATCTCTATTTGAGAATAGACCCTTACTAGGAAGAACGTT TTTTCCTCAGTGCATTTGTGCTAGAAATTTTCAAGAGTCTAATAGTCTTTGCCAGTCATTCAGCAGCAAA TTTTCAGCATTAAGCTGTTCCTGTTCAGTAATAAAACCGGTCACTGATGGGAAAACTGCCAATATAGAAA AATAAAAATCTCTTTTCCACTCCATTGTCGTATAGGCATGTAAACAGCCTCTTTTTGATACTGGAGGAAC ACTTGATGGAGTGTGAGCCACCTAAGATCTCGGTTTGCCAAAATTCATTTCTAATTAACCTTACTAATTA TACTACTTTGTTAGGATTTTCACATTCTTGGCTTAATCATTTTCATTCCTAAAGAAAAATATCTTGGCCT AAACCTCAGTTATTACATGTAATTTGATGAGGTATTTTTTCCTTTTTTCTTTTTTTTTTTTTTTTTTTTT TGAGACAGTCTTGCTCTATCGCCCAGGCTGGAGTGCAGTGGCGCATTCTAGGCTCACTGCAACTTCTGCC TCCCATGCTTACGTGATCCTCTCACCTCAGCCTCTCAAGTAATATAGCTGAGACTACAAGTGTGTGCCAC CATGCCTCACTAATTTTTGTATTATTTTTGTAGAGACGGTGTTTTGCCATGTTGGCCAGGCTGGTCTTGA ACTCCTGGACTCAAGCAACCTACCCAGCGTGGCCTCCCAAAGTGCTGGGATTACAGACACGAGCCACCTC ACCTAGCCTGATGAGATTTTTAAAAAATATTTTCTCTGTACTTTTCATTCTCTTTTAATGAGGACCAATG TACAGTTGAAATAACTGGAACAAATTATTTTTGGTGTGTGTGACAATTCTGTTTTTAATGCTATTTGAAC AAGTGGGCCATTAGCCAGATTTGTCTTTTTGTTGTAAAACAAAATTTGACTAATTTTACATGTTTATAAA TCTTATGCTCTCACTGTTTGTTTTTATTTAAATTACAATTTTATCTGTTTCCTGACATTGTCTCCTATAT ATTTCTATTATTAATTGCAAAAACATAGAAATGGAAATTTTGCTATCAACAATAAAATTTTTTTAAAGTA GTGAGTGCTATTTTGGAGTTCCAAATTTTCAGTAGGAAGTATCTAAAACTTTTTTTAATACGTGCCATTA TCTATAGAAAACATTACTTCAGGTTGTGAGATTGAGTTGCATTTCTGGATGGACTGATGAATTTATCCGA CATGAAGAAGATTGGCATATTAGCTTTAAAAATTTTTAAAGATTGGATTTTTTTTAGTATAAGCACTTTC TAAGGATTATAGAGAAATGTTTCACCTCCAATGCATAGCAAAAATAGTGGTGTTAGAAAGAAAATAGGTT ACATTTAAGGAAGGTGCTTTAAAAAGCAGAAGCAGACTTTAAAATTAAATTTGTGGACACCTTTTTAAAA ATTGAATCAAAGATTATAATTTAGATATACAATAACACCTATATATAGATAAGTTTTAACACTGAGTTTT CTTTCAGACTGTTTTCTAACTACATAGAC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_003921.4 |
Summary | This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
Locus ID | 8915 |
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