Mms19 (NM_028152) Mouse Untagged Clone

CAT#: MC203350

Mms19 (untagged) - Mouse MMS19 (MET18 S. cerevisiae) (Mms19), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Mms19
• Synonyms: 2410001K24Rik; 2610042O15Rik; AI316855; C79368; C86341; Mms19l
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC050817
  GTCATGGCTGCCGCCACCGGTCTGGAGGAGGCAGTGGCGCCTATGGGCGCCCTGTGTGGCCTCGTGCAAG ACTTCGTCATGGGTCAACAGGAGGGGCCCGCTGACCAGGTGGCTGCAGATGTGAAGTCCGGTGGCTATAC AGTGTTACAAGTAGTAGAAGCCCTTGGGTCCTCTCTGGAAAATGCTGAACCCCGAACTCGGGCTCGAGGA GCCCAGCTTCTGTCACAGGTGCTGCTCCAGTGTCACTCCTTGCTCTCGGAGAAGGAAGTGGTCCACCTGA TCCTGTTCTATGAGAACCGGCTGAAGGACCACCATCTTGTGGTCCCATCTGTCTTACAGGGCCTGAGGGC ACTGAGCATGTCTGTGGCCCTGCCTCCGGGTCTGGCTGTCTCTGTGCTTAAAGCCATCTTCCAGGAGGTA CATGTACAGTCCCTGCTACAGGTGGACCGCCATACTGTCTTCAGCATCATCACTAACTTCATGCGATCAC GAGAAGAAGAGCTGAAGGGTCTGGGAGCTGACTTCACATTTGGCTTCATCCAGGTGATGGATGGGGAGAA GGATCCCCGTAATCTCCTGCTGGCTTTCCGCATCGTCCATGACCTCATCTCCAAGGACTACAGTCTGGGA CCTTTCGTGGAAGAGTTATTTGAAGTGACATCTTGTTATTTCCCTATTGATTTTACCCCTCCGCCTAACG ATCCTTATGGCATCCAGAGAGAGGATCTCATCCTGAGTCTCCGTGCTGTGCTGGCGTCTACACCGCGCTT TGCCGAGTTCTTACTGCCTCTGCTAATTGAGAAAGTGGATTCGGAGATTTTAAGTGCCAAGCTGGATTCT CTGCAAACTCTGAATGCTTGCTGTGCTGTGTATGGACAGAAGGAGCTGAAGGACTTCCTGCCCAGCCTTT GGGCTTCCATCCGTAGAGAGGTTTTCCAGACTGCTAGTGAGCGAGTAGAGGCAGAGGGCCTGGCAGCTCT CCACTCCCTGACTGCGTGTCTGTCCTGCTCTGTGCTGAGAGCTGATGCTGAGGACCTCCTTGGTTCCTTC CTCAGCAACATCCTTCAAGACTGCAGGCACCATCTATGTGAACCAGACATGAAACTTGTATGGCCTAGCG CTAAGCTGTTGCAGGCAGCTGCAGGTGCGTCTGCCCGGGCCTGTGAGCACCTCACCAGCAACGTGCTTCC CTTGCTGCTGGAACAGTTCCACAAGCACAGCCAGAGCAACCAGCGTCGGACAATCCTTGAAATGATCCTG GGATTCCTAAAGCTACAGCAGAAATGGAGCTATGAAGACAGAGATGAAAGGCCTCTGAGTAGCTTCAAAG ACCAGCTATGCTCATTGGTGTTCATGGCTCTAACAGACCCCAGCACCCAGCTTCAGCTTGTTGGCATCCG GACGCTCACAGTCTTGGGTGCCCAGCCAGGTCTCCTGTCTGCTGAGGACTTGGAGCTGGCAGTAGGTCAC CTGTACCGACTGACCTTCCTGGAGGAAGATTCCCAGAGTTGTAGGGTGGCCGCACTGGAGGCATCAGGAA CCCTGGCCACTCTGTATCCTGGAGCCTTCAGCAGACACTTGCTCCCCAAGCTTGCTGAGGAGCTGCATAA AGGGGAGTCAGATGTGGCTAGAGCAGATGGTCCCACCAAATGTTCCCGGCATTTCCGCTGTCTGCAAGCT TTGTCAGCTGTTTCAACACATCCCAGCATTGTCAAGGAGACACTGCCTCTGCTACTGCAGCATCTCTGTC AAGCAAACAAAGGGAATATGGTTACAGAGTCCAGTGAAGTTGTTGCTGTCTGTCAGAGTCTCCAGCAGGT GGCAGAAAAATGCCAGCAGGACCCTGAGAGCTACTGGTATTTCCACAAGACAGCTGTACCCTGCCTGTTT GCATTGGCTGTGCAGGCTTCAATGCCAGAGAAGGAATCCTCAGTTCTGAGAAAAGTACTGTTGGAGGATG AGGTCTTGGCTGCGTTGGCATCTGTCATTGGCACTGCCACTACCCATCTGAGCCCTGAACTAGCTGCCCA GAGCGTCACATGCATCGTGCCCCTCTTCTTAGATGGCAACACTTCCTTTCTACCTGAAAACAGCTTCCCT GACCAGTTCCAGCCGTTCCAGGATGGCTCCTCTGGGCAGAGGCGGCTGGTTGCACTACTTACGGCTTTTG TCTGCTCCCTGCCACGAAATGTGGAAATCCCTCAGCTGAACCGACTCATGCGGGAGCTTTTGAAGCAGAG CTGTGGCCACAGCTGTCCTTTCTCCTCCACTGCCGCCACTAAGTGCTTTGCAGGGCTCCTCAACAAGCAG CCTCCAGGGCAGCAGTTGGAGGAGTTCCTCCAGCTCGCTGTGGGCACAGTGGAGGCGGGCCTGGCCTCTG AATCCTCCCGTGATCAGGCTTTCACACTGCTGCTCTGGGTAACCAAGGCTCTAGTCCTCAGATACCATCC TCTCAGTGCCTGCCTGACCACCCGGCTCATGGGCCTCCTCAGTGATCCAGAACTTGGCTGTGCAGCAGCT GATGGCTTCTCTCTGCTCATGTCTGACTGCACTGATGTGTTGACTCGTGCCGGCCATGCTGATGTTCGGA TCATGTTCCGCCAGCGGTTCTTCACAGACAATGTGCCTGCTTTGGTCCAAGGTTTCCATGCCGCTCCCCA AGATGTGAAGCCAAACTATCTGAAGGGTCTGTCTCACGTACTCAACAGGCTGCCCAAGCCTGTGCTTTTA CCAGAGCTGCCCACACTTCTTTCCTTGCTGCTGGAAGCATTATCCTGCCCTGACTCTGTGGTCCAGCTTT CCACTCTGAGCTGTCTCCAACCCCTACTACTGGAAGCACCTCAAATCATGAGTCTTCATGTTGACACTCT GGTTACAAAATTCCTGAACCTCAGCTCCAGTTACTCAATGGCTGTCCGGATTGCTGCTCTGCAGTGTATG CACGCTCTCACTCGCCTCCCCACTTCTGTGCTACTGCCATACAAATCTCAGGTCATCCGAGCCTTAGCCA AGCCTCTGGACGACAAGAAGAGACTTGTGCGAAAGGAAGCAGTGTCAGCGAGGGGAGAATGGTTCCTACT TGGGAGCCCGGGGAGCTGAGCCCTTGGTCCTGGCCTAAACCCTCCTGACAATCTAACCTGCAAGTACTAA CTATTGAGCCATCCCACAAGGCAAGACTACTGGTCTGCCTTCCCATGGATGCAGTACAAATGCTGGGCCT CCTGCATGGCTGTGCAAAACTCTTAAAGAGCCATGACTTCTAATGGATTGTTGAAGAGACTGAGACTTGT ATTTGAGGAAAAGACCTTGGATGTTGGGGCTCTCCCGTGTCTGTCAGGAATAGGAAGCTGTGCTGCTGAA GGGTCAGTGCAGTGGAGTGTGACCTCGAGAACTGGGGTTGGTGTTACATGAGTTCACCTGCCAGAGAATA AAGCCTTCTTTGTAATGGGCACACTCACGTGTACTGCCTTATTCTACAGATGCTAGAGAAGCACACACCG AGAGCTCCCAGTTCTTCAGTACAGCACCGAGGCACAGAGAAGCTACATATCTTTTTACAAATCAAATGCC TTTATTTTCGCTCCCTCTGTAGCACGTGAGAAATGGCAGTGACCTTGGCAATAGGCTTACTGTCTTTGTC CCGTTGAGAAGCCAGAGTTTCAACATACCTGATGGATCTTTTCCCAAAGTGAAAGAAAGAGATGGTGTCT AGCCCCAGTGCTGTGACCTAGAGCTCGGCTGGAGCTAAAACTTATTTGCCTGAGTAAAGGGACTTCAATC CTTGAGTTTCTCCACACTGCATCTTGTTTTTAGGTGGCAGAAGATTGGTCTTGATTGTCCCTGTGTAGTA CTCTAAGGCAAGCCTGATGGCTCTTCATGGTCATGGATTCCAGGAAAAGCTGCCCTTGGAAGCTCTTGAG AGACAATAAACATCAAATAGTGTTCAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_028152
• ORF Size: 3096 bp
• Insert Size: 3096
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC050817, AAH50817
• RefSeq Size: 3959
• RefSeq ORF: 3096
• Locus ID: 72199
• Gene Summary: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery. [UniProtKB/Swiss-Prot Function]