Cldn10 (NM_021386) Mouse Untagged Clone

CAT#: MC204128

Cldn10 (untagged) - Mouse claudin 10 (Cldn10), transcript variant b, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Cldn10
• Synonyms: 6720456I16Rik; Cldn10a; Cldn10b; D14Ertd728e
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC029019
  CGGGAACCAGCGAGAGCGCCGCTGCAGCCCAGCATGGCTAGCACGGCCTTGGAAATCGTCGCCTTCGTAG TCTCCATCTCGGGCTGGGTGCTAGTGTCTTCCACACTGCCCACCGACTACTGGAAGGTCTCCACCATCGA TGGCACTGTCATCACCACAGCCACTTATTTTGCCAACCTGTGGAAGATCTGCGTTACCGATTCCACCGGT GTCGCCAACTGCAAGGAGTTCCCCTCCATGCTGGCGTTGGATGGTTACATCCAGGCATGTAGAGGACTAA TGATCGCTGCGGTCAGCCTGGGATTTTTCGGTTCCATTTTTGCACTCTTTGGAATGAAATGTACCAAAGT CGGAGGCTCAGATCAAGCCAAAGCTAAAATCGCTTGCTTGGCCGGGATTGTATTCATATTGTCAGGTCTG TGTTCCATGACAGGCTGTTCCCTGTATGCAAACAAAATCACAACAGAATTCTTTGATCCTCTCTATATGG AGCAAAAGTATGAATTAGGGGCTGCTCTCTTCATCGGATGGGCAGGAGCTTCTCTCTGCATCATTGGGGG AGTCATATTTTGCTTTTCAATATCCGACAACAATAAGACACCCAGAATGGGCTACACATACAACGGACCC ACGTCTGTCATGTCTTCTCGGACCAAGTATCAAGGCGGAGAAGGAGATTTTAAAACCGCAGGCCCTTCAA AACAGTTTGATAAAAATGCCTATGTCTAAAGAGCTCTGGCAAGCTGCCTCCTGAGTTTTGTTGTGCAAGA GAACTGTCCTCACAATAGTCCTTCCAAGGCTCTCCTGTAATTACTGCTTAAGCTGTTTTTTAAAAATATA AATTTGAAGAATGTTAATTGGATGTAAATGTTCTTATAGTTATATACTAATCATTTTCTGCTGTGCCTTT CTGTAAGGGAAATAAACAGGTTATTTACAGGGTGTGTATATTTTATACACATAGAAGACATGGGTACCCT TAGTTCATAAGGCTCAGGGAATGGTAGCCACTGGATCCTTAATGTGCTGAGAGCTTCCCTCGTTCCACCC ACAGATCAAACACAAGTGTGCAGACGATGGATGGTGTCGTGTGAAGGGGACAGCGATAATCTCAGACCCC TCATCCAGTATCCAAGTCAAACAATCACACAACCAATGTGCCATGTCGTTGATTTCTAGTTTCTTGGTTC TGTCCATCAGGGCTGTCATTTGTCATGATGGCCAAAGAAAGGGCTGGTGAGGCCAAGGTGCCTTTGCCCT GTGTGTGGACCATAAACCACACGGGCTTGTCTGAGCGAGAGCATGTGACCACTAGCTGAGCTGGCCACTG GTGGCGGCTGAATCTAAAGCCAGCTAAGGAAGCTCTGGGGCCTGTGTGGGCCTGGCTCTCTCATTTCCTG TGTCCCACGGGTCTGCACCCAACACTCACTAGGTCACTGAGACACTGGCCATTTTTCAAGGCATGGAACT TGATCAGGTGGTTTTGGAACAAAGATGCAGGTGAATTCCTGAGGCCAGCCCTGCATGTCACTTACCCACA AAGGCAGTAATTGTTCTCACTAGCACACAGCTTATAGGTCAGAGCACATTCACCCTTACACACCCCCTTA ACCGTTGGTGCTTACATTTTCCTGCGTGTGCAGTGAAGAAACGTAGAGTAGGGAGCCCTGTAGTGTCAGA ACCAGGGCGTGAGCTGGTCTAGGGTAAAATACATGGTTTCAAGTTGTAAGAACTGGTACTTCTGTCATAT GCTATAAATCGCCCACAACGAGTCACATGGCTGACTACATGACTTTCCCAGAGGGTAAAAGACTGAAAAG GAAATAGAGGACACTGTTTGCAGGGATTCAACGGAAAGGAAAGGAAAGGAAACTTTTTTTTAAAAAAGTA AAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_021386
• ORF Size: 696 bp
• Insert Size: 696
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC029019, AAH29019
• RefSeq Size: 1904
• RefSeq ORF: 696
• Locus ID: 58187
• Gene Summary: This intronless gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight unction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Six alternatively spliced transcript variants have been identified, which encode different isoforms with distinct electric charge of the first extracellular loop and with or without the fourth transmembrane region. These isoforms exhibit distinct localization and function in paracellular anion or cation permeability. [provided by RefSeq, Aug 2010]
  Transcript Variant: This variant (b) differs in the 5' UTR and 5' coding region, representing use of an alternate promoter, compared to variant a. The resulting isoform (b) has a longer and distinct N-terminus, compared to isoform a. This variant is expressed in all tissues tested, with lowest expression in liver and highest expression in kidney.