Cldn7 (NM_016887) Mouse Untagged Clone

CAT#: MC204654

Cldn7 (untagged) - Mouse claudin 7 (Cldn7), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Cldn7
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC050007
  CCTGCCGCCGCACCGCCAGCTCCCTGTGCCGCGCACCGCAGCCTGGGGCCCAAGGGCCCGCATACTTTCT GGGGGCCACGCCCTAACGGCCCCTCCACTTCTTTGGGTAGTCTCGGAGCACGCCGGTAGGAACCGCCCGG CCTTCGGGGACCGCTTTTGTCTGGAACCAGTCCTTCGGGCGAAGCCGGTTCCCTCTGCTGTGAGAGTGTC GCTTCACCGGAGGGGACGATTTGTGTTTACCTCGGTTAACAAGATTTGTAGTTACCCGGTCCAAAAAAAA ATCTTTTTCTCCTTTGGGTGACTTAAATCTCTATCCAAATTTTCTTGTGTTGCTGCTCCCCGGATTTTTG TTTTTTTGTTTTTTTGCTTTACTGTAGGGTCGCCCTCCCGGCGCGTCCCGTCTTTTCTGAGACAAGGAAA TGGCCAACTCGGGCCTGCAACTGCTGGGCTTTTCAATGGCCATGCTTGGCTGGGTGGGCCTGATAGCGAG CACTGCCATCCCTCAGTGGCAGATGAGCTCCTATGCGGGCGACAACATCATCACAGCCCAGGCCATGTAC AAGGGGCTCTGGATGGAGTGCGTCACGCAGAGCACCGGCATGATGAGCTGCAAAATGTACGACTCGGTGC TCGCCCTGCCGGGAGCCCTGCAGGCCACTCGAGCCTTAATGGTGGTGTCCCTGGTGTTGGGCTTCTTAGC CATGTTTGTCGCCACGATGGGCATGAAGTGCACACGCTGTGGGGGAGATGACAAAGCGAAGAAGGCCCGA ATAGCTATGACTGGAGGCATTGTTTTCATTGTGGCAGGTCTTGCTGCCTTGGTAGCATGTTCCTGGATTG GTCATCAGATTGTCACAGACTTTTATAACCCCTTGACGCCCATGAACGTTAAGTACGAGTTTGGACCTGC CATCTTTATCGGCTGGGCAGGGTCTGCTCTGGTCCTTCTGGGAGGTGCCCTGCTCTCTTGCTCCTGTCCA GGCAGTGAAAGCAAAGCTGCGTACCGAGCACCCCGCTCTTACCCCAAGTCCAATTCCTCCAAGGAATACG TGTGAGCTGGGGAGCCCAGCCTGCGGGCAGGGTGGGAGGCAAAGGCCTCCTGGCCACTCCACCTCCAAAC ATCATGTATAGTTTGCTTGGGGGGAGGGCAGTTGGGGGGTTACTGGGAGAGGAAGACATGGGGTGTGCTT TTGTACAGAAATAAAATTAAGTTTTGGAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_016887
• ORF Size: 636 bp
• Insert Size: 636
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC050007, AAH50007
• RefSeq Size: 1235
• RefSeq ORF: 636
• Locus ID: 53624
• Gene Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed constitutively in the mammary epithelium throughout development, and might be involved in vesicle trafficking to the basolateral membrane. It is essential for NaCl homeostasis in distal nephrons. The knockout mice lacking this gene showed severe salt wasting, chronic dehydration, and growth retardation, and died within 12 days after birth. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]
  Transcript Variant: This variant (1) and variant 2 encode the same protein.