Hbegf (NM_010415) Mouse Untagged Clone

CAT#: MC208020

Hbegf (untagged) - Mouse heparin-binding EGF-like growth factor (Hbegf), (10ug)


  "NM_010415" in other vectors (5)

Reconstitution Protocol

USD 420.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Symbol Hbegf
Synonyms AW047313; Dtr; Dts; Hegfl
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>MC208020 representing NM_010415
Red=Cloning site Blue=ORF Green=Tags(s)

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGAAGCTGCTGCCGTCGGTGATGCTGAAGCTCTTTCTGGCCGCAGTGTTGTCCGCGTTGGTGACCGGTG
AGAGTCTGGAGCGGCTTCGGAGAGGTCTGGCGGCAGCAACCAGCAACCCTGACCCTCCCACTGGATCCAC
AAACCAGCTGCTACCCACGGGAGGTGATCGTGCTCAGGGGGTCCAGGACTTGGAAGGGACAGATCTGAAC
CTTTTCAAAGTTGCTTTCTCCTCCAAGCCACAAGGCCTGGCCACCCCAAGCAAAGAAAGGAATGGGAAAA
AGAAGAAGAAAGGAAAGGGGTTAGGGAAGAAGAGAGACCCATGCCTCAGGAAATACAAGGACTACTGCAT
CCACGGGGAGTGCAGATACCTGCAGGAGTTCCGTACTCCCTCTTGCAAATGCCTCCCTGGTTACCACGGA
CACAGGTGTCATGGGCTGACTCTACCAGTGGAGAATCCCCTATACACATATGACCACACTACAGTCTTGG
CTGTGGTGGCTGTAGTACTGTCGTCCGTCTGTCTTCTTGTCATCGTGGGACTTCTCATGTTTAGGTACCA
CAGGAGAGGAGGTTATGACTTGGAAAGTGAAGAGAAAGTGAAGTTGGGCGTGGCTAGCTCCCACTGA


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAG
GTTTAA
Chromatograms CHROMATOGRAMS
Sequencher program is needed, download here.
Restriction Sites SgfI-MluI     
ACCN NM_010415
ORF Size 627 bp
Insert Size 627
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Reference Data
RefSeq NM_010415.1, NP_034545.1
RefSeq Size 2337
RefSeq ORF 627
Locus ID 15200
Gene Summary Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor. [UniProtKB/Swiss-Prot Function]

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