Bmp2 (NM_007553) Mouse Untagged Clone

CAT#: MC208194

Bmp2 (untagged) - Mouse bone morphogenetic protein 2 (Bmp2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Bmp2
• Synonyms: AI467020; Bmp2a
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC208194 representing NM_007553
  Red=Cloning site Blue=ORF
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGTGGCCGGGACCCGCTGTCTTCTAGTGTTGCTGCTTCCCCAGGTCCTCCTGGGCGGCGCGGCCGGCC
  TCATTCCAGAGCTGGGCCGCAAGAAGTTCGCCGCGGCATCCAGCCGACCCTTGTCCCGGCCTTCGGAAGA
  CGTCCTCAGCGAATTTGAGTTGAGGCTGCTCAGCATGTTTGGCCTGAAGCAGAGACCCACCCCCAGCAAG
  GACGTCGTGGTGCCCCCCTATATGCTAGATCTGTACCGCAGGCACTCAGGCCAGCCAGGAGCGCCCGCCC
  CAGACCACCGGCTGGAGAGGGCAGCCAGCCGCGCCAACACCGTGCGCAGCTTCCATCACGAAGAAGCCGT
  GGAGGAACTTCCAGAGATGAGTGGGAAAACGGCCCGGCGCTTCTTCTTCAATTTAAGTTCTGTCCCCAGT
  GACGAGTTTCTCACATCTGCAGAACTCCAGATCTTCCGGGAACAGATACAGGAAGCTTTGGGAAACAGTA
  GTTTCCAGCACCGAATTAATATTTATGAAATTATAAAGCCTGCAGCAGCCAACTTGAAATTTCCTGTGAC
  CAGACTATTGGACACCAGGTTAGTGAATCAGAACACAAGTCAGTGGGAGAGCTTCGACGTCACCCCAGCT
  GTGATGCGGTGGACCACACAGGGACACACCAACCATGGGTTTGTGGTGGAAGTGGCCCATTTAGAGGAGA
  ACCCAGGTGTCTCCAAGAGACATGTGAGGATTAGCAGGTCTTTGCACCAAGATGAACACAGCTGGTCACA
  GATAAGGCCATTGCTAGTGACTTTTGGACATGATGGAAAAGGACATCCGCTCCACAAACGAGAAAAGCGT
  CAAGCCAAACACAAACAGCGGAAGCGCCTCAAGTCCAGCTGCAAGAGACACCCTTTGTATGTGGACTTCA
  GTGATGTGGGGTGGAATGACTGGATCGTGGCACCTCCGGGCTATCATGCCTTTTACTGCCATGGGGAGTG
  TCCTTTTCCCCTTGCTGACCACCTGAACTCCACTAACCATGCCATAGTGCAGACTCTGGTGAACTCTGTG
  AATTCCAAAATCCCTAAGGCATGCTGTGTCCCCACAGAGCTCAGCGCAATCTCCATGTTGTACCTAGATG
  AAAATGAAAAGGTTGTGCTAAAAAATTATCAGGACATGGTTGTGGAGGGCTGCGGGTGTCGTTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_007553
• ORF Size: 1185 bp
• Insert Size: 1185
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: BC100344, AAI00345
• RefSeq Size: 2540
• RefSeq ORF: 1185
• Locus ID: 12156
• Gene Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. While a homozygous knockout mouse for this gene exhibits embryonic lethality, conditional knockout mice have defects in bone, cartilage and heart development. [provided by RefSeq, Jul 2016]