Tgfb3 (NM_009368) Mouse Untagged Clone

CAT#: MC209523

Tgfb3 (untagged) - Mouse transforming growth factor, beta 3 (Tgfb3), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Tgfb3
• Synonyms: TGF-beta-3; Tgfb-3
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC209523 representing NM_009368
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAAGATGCACTTGCAAAGGGCTCTGGTAGTCCTGGCCCTGCTGAACTTGGCCACAATCAGCCTCTCTC
  TGTCCACTTGCACCACGTTGGACTTCGGCCACATCAAGAAGAAGAGGGTGGAAGCCATTAGGGGACAGAT
  CTTGAGCAAGCTCAGGCTCACCAGCCCCCCTGAGCCATCGGTGATGACCCACGTCCCCTATCAGGTCCTG
  GCACTTTACAACAGCACCCGGGAGTTGCTGGAAGAGATGCACGGGGAGAGGGAGGAAGGCTGCACTCAGG
  AGACCTCGGAGTCTGAGTACTATGCCAAAGAGATCCATAAATTCGACATGATCCAGGGACTGGCGGAGCA
  CAATGAACTGGCCGTCTGCCCCAAAGGAATTACCTCTAAGGTTTTTCGTTTCAATGTGTCCTCAGTGGAG
  AAAAATGGAACCAATCTGTTCCGGGCAGAGTTCCGGGTCTTGCGGGTGCCCAACCCCAGCTCCAAGCGCA
  CAGAGCAGAGAATTGAGCTCTTCCAGATACTTCGACCGGATGAGCACATAGCCAAGCAGCGCTACATAGG
  TGGCAAGAATCTGCCCACAAGGGGCACCGCTGAATGGCTGTCTTTCGATGTCACTGACACTGTGCGCGAG
  TGGCTGTTGAGGAGAGAGTCCAACTTGGGTCTGGAAATCAGCATCCACTGTCCATGTCACACCTTTCAGC
  CCAATGGAGACATACTGGAAAATGTTCATGAGGTGATGGAAATCAAATTCAAAGGAGTGGACAATGAAGA
  TGACCATGGCCGTGGAGACCTGGGGCGTCTCAAGAAGCAAAAGGATCACCACAACCCACACCTGATCCTC
  ATGATGATCCCCCCACACCGACTGGACAGCCCAGGCCAGGGCAGTCAGAGGAAGAAGAGGGCCCTGGACA
  CCAATTACTGCTTCCGCAACCTGGAGGAGAACTGCTGTGTACGCCCCCTTTATATTGACTTCCGGCAGGA
  TCTAGGCTGGAAATGGGTCCACGAACCTAAGGGTTACTATGCCAACTTCTGCTCAGGCCCTTGCCCATAC
  CTCCGCAGCGCAGACACAACCCATAGCACGGTGCTTGGACTATACAACACCCTGAACCCAGAGGCGTCTG
  CCTCGCCATGCTGCGTCCCCCAGGACCTGGAGCCCCTGACCATCTTGTACTATGTGGGCAGAACCCCCAA
  GGTGGAGCAGCTGTCCAACATGGTGGTGAAGTCGTGTAAGTGCAGCTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_009368
• ORF Size: 1239 bp
• Insert Size: 1239
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_009368.3, NP_033394.2
• RefSeq Size: 3401
• RefSeq ORF: 1239
• Locus ID: 21809
• Gene Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Homozygous knockout mice for this gene exhibit cleft palate, delayed pulmonary development and neonatal death. [provided by RefSeq, Aug 2016]