Oas1b (NM_001083925) Mouse Untagged Clone

CAT#: MC209687

Oas1b (untagged) - Mouse 2'-5' oligoadenylate synthetase 1B (Oas1b), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Oas1b
• Synonyms: Flv; L1; Mmu-L1; Oas1; Oias-2; Oias2; Wnv
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC209687 representing NM_001083925
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGCAGGATCTGAGGAGCATCCCGGCCTCGAAGCTTGATAAGTTCATAGAGAACCATCTCCCGGACA
  CCAGCTTCTGTGCTGACCTCAGAGAAGTCATAGATGCCCTGTGTGCTCTCCTGAAGGACAGATCCTTCCG
  GGGCCCCGTCCGCCGAATGAGGGCCTCTAAAGGGGTCAAGGGCAAAGGCACCACACTCAAGGGCAGGTCA
  GACGCTGACCTGGTGGTGTTCCTTAACAATCTCACCAGCTTTGAGGATCAGTTAAACCAACAGGGAGTGT
  TGATTAAGGAAATTAAGAAACAGCTGTGCGAGGTTCAGCATGAGAGACGTTGTGGAGTGAAGTTTGAGGT
  CCACAGTTTAAGGAGTCCCAACTCCCGGGCTCTGAGCTTCAAGCTGAGCGCCCCCGACCTGCTGAAGGAG
  GTGAAGTTTGATGTGCTGCCAGCCTATGATTTACTGGATCATCTTAACATCCTCAAGAAGCCTAACCAAC
  AATTCTACGCCAATCTCATCAGTGGGCGTACCCCGCCGGGGAAGGAGGGCAAGTTATCGATCTGCTTTAT
  GGGGCTTCGGAAGTACTTCCTGAACTGTCGCCCAACCAAGCTGAAGCGCCTCATCCGCCTGGTCACGCAC
  TGGTACCAACTGTGTAAGGAGAAGCTGGGGGACCCGCTGCCCCCACAGTATGCCCTGGAGCTGCTCACAG
  TCTATGCCTGGGAGTATGGGAGTCGAGTAACTAAATTCAACACAGCCCAGGGCTTCCGAACCGTCTTGGA
  ACTGGTCACCAAGTACAAACAGCTTCGAATCTACTGGACAGTGTATTATGACTTTCGACATCAAGAGGTC
  TCTGAATACCTGCACCAACAGCTCAAAAAAGACAGGCCTGTGATCTTGGACCCCGCTGACCCAACAAGGA
  ACATAGCTGGTTTGAACCCAAAGGACTGGCGGCGTCTAGCAGGAGAGGCTGCCACCTGGCTGCAATACCC
  ATGCTTTAAGTACAGGGACGGTTCCCCAGTGTGCTCCTGGGAGGTGCCGACGGAGGTTGGAGTGCCAATG
  AAGTATCTCTTTTGTCGTATTTTCTGGTTATTGTTTTGGTCTTTGTTTCATTTCATCTTTGGGAAGACTT
  CATCTGGATAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001083925
• ORF Size: 1131 bp
• Insert Size: 1131
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001083925.1, NP_001077394.1
• RefSeq Size: 1837
• RefSeq ORF: 1131
• Locus ID: 23961
• Gene Summary: This gene is a member of the 2'-5' oligoA synthetase family, which are clustered on chromosome 5. The encoded protein functions in the interferon-regulated OAS/RNase L system, which mediates RNA decay as part of the innate antiviral immunity pathway. The protein binds double-stranded RNA and oligomerizes ATP, which activate the single-stranded RNA cleavage enzyme RNase L. This protein mediates resistance to flaviviruses such as West Nile virus. The majority of wild mouse strains produce a functional protein and are resistant to flavivirus infection, whereas some inbred mouse strains including the strain of the reference genome, C57BL/6J, contain a premature stop codon that inactivates this gene product. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1, coding) represents the functional allele that is not present in some strains, including the strain of the reference genome. Sequence Note: This RefSeq record was created to represent the transcript and the full-length, functional protein that is expressed in several strains. It does not contain a premature stop codon that truncates the coding region of several strains, including the strain of the reference genome, C57BL/6J.