Lgmn (NM_011175) Mouse Untagged Clone

CAT#: MC215719

Lgmn (untagged) - Mouse legumain (Lgmn), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Lgmn
• Synonyms: AEP; AI746452; AU022324; Prsc1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC215719 representing NM_011175
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGACCTGGAGAGTGGCTGTGCTTCTCAGCCTGGTGCTGGGTGCTGGTGCCGTTCCCGTCGGTGTGGACG
  ATCCCGAGGATGGAGGCAAGCACTGGGTGGTGATTGTGGCGGGCTCCAATGGCTGGTATAATTACCGACA
  CCAGGCAGACGCATGCCACGCCTACCAGATCATCCACCGGAACGGGATTCCTGACGAGCAGATCATAGTG
  ATGATGTATGACGACATTGCCAACTCTGAAGAAAACCCTACCCCAGGTGTTGTGATCAACCGACCTAACG
  GCACAGATGTATACAAGGGAGTCCTGAAGGACTACACCGGAGAGGATGTGACTCCAGAGAATTTCCTCGC
  CGTGCTGAGAGGTGACGCAGAAGCTGTGAAGGGCAAAGGGTCTGGAAAAGTCTTGAAGAGTGGCCCCCGA
  GATCATGTCTTCATTTACTTCACCGACCACGGAGCCACCGGGATCCTGGTGTTTCCTAATGATGATCTTC
  ATGTCAAGGACCTGAATAAGACTATTCGCTACATGTATGAACACAAAATGTACCAGAAGATGGTGTTCTA
  CATTGAAGCTTGTGAGTCTGGCTCCATGATGAACCACCTGCCCGACGACATCAACGTTTATGCAACTACT
  GCGGCCAACCCCAAGGAGTCATCTTATGCCTGCTACTACGACGAGGAGAGGGGCACTTACCTGGGTGACT
  GGTACAGCGTCAACTGGATGGAAGACTCCGATGTGGAGGACCTGACCAAAGAGACCCTTCACAAGCAGTA
  CCACCTGGTCAAGTCCCACACCAACACCAGCCATGTCATGCAATATGGGAACAAATCTATCTCTACCATG
  AAAGTGATGCAGTTTCAGGGAATGAAGCACAGAGCCAGTTCCCCCATCTCCCTGCCTCCGGTCACACACC
  TTGACCTCACCCCCAGCCCTGACGTGCCCCTGACCATCTTGAAGAGGAAGCTGCTGAGAACCAACGACGT
  GAAGGAATCCCAGAATCTCATTGGGCAGATCCAGCAATTTCTGGATGCCAGGCACGTCATTGAGAAGTCT
  GTGCACAAGATCGTTTCCCTGCTGGCGGGATTTGGGGAAACTGCTGAGAGACATCTGTCAGAGAGGACCA
  TGCTCACAGCACATGACTGCTACCAGGAGGCTGTAACCCACTTCCGCACACACTGCTTTAACTGGCACTC
  TGTCACGTACGAGCATGCCTTGCGGTACTTGTATGTGCTGGCCAATCTCTGTGAGGCACCATATCCGATT
  GACAGGATAGAGATGGCCATGGACAAAGTGTGTCTTAGTCACTACTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_011175
• ORF Size: 1308 bp
• Insert Size: 1308
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_011175.2, NP_035305.1
• RefSeq Size: 1874
• RefSeq ORF: 1308
• Locus ID: 19141
• Gene Summary: This gene encodes a member of the cysteine peptidase family C13 that plays an important role in the endosome/lysosomal degradation system. The encoded inactive preproprotein undergoes autocatalytic removal of the C-terminal inhibitory propeptide to generate the active endopeptidase that cleaves protein substrates on the C-terminal side of asparagine residues. Mice lacking the encoded protein exhibit defects in the lysosomal processing of proteins resulting in their accumulation in the lysosomes, and develop symptoms resembling hemophagocytic lymphohistiocytosis. [provided by RefSeq, Aug 2016]