Crbn (BC086488) Mouse Untagged Clone

CAT#: MC218344

Crbn (untagged) - Mouse cereblon (cDNA clone MGC:103113 IMAGE:30443656), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Crbn
• Synonyms: piL
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC086488
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGAAACCACCTGCCGCTTCTGCCTGACAGTGAAGATGAAGATGATGAAATTGAAATGGAAGTTGAAG
  ACCAAGATAGTAAAGAAGCCAGAAAACCGAATATCATAAACTTTGACACCAGTCTGCCAACCTCACATAC
  ATACCTGGGAGCTGATATGGAGGAGTTCCACGGGAGAACTTTGCATGACGACGACAGCTGCCAGGTGATC
  CCAGTCCTTCCTGAGGTGCTGATGATCCTGATTCCTGGGCAGACACTCCCACTGCAGCTCTCTCACCCAC
  AGGAAGTCAGCATGGTGCGGAACTTAATCCAGAAAGACAGGACCTTTGCAGTCCTTGCATACAGTAATGT
  GCAAGAAAGGGAAGCACAGTTTGGGACAACAGCAGAGATCTATGCCTATCGAGAAGAGCAGGAGTTTGGA
  ATTGAAGTAGTGAAAGTGAAAGCAATTGGAAGGCAGCGGTTCAAGGTCCTCGAACTTCGAACACAGTCAG
  ATGGAATCCAGCAAGCTAAAGTGCAGATTTTGCCAGAGTGTGTGTTGCCGTCAACCATGTCTGCAGTGCA
  GGTAGAATCACTCAATAAGTGCCAGGTATTTCCTTCAAAACCCATCTCCTGGGAAGACCAGTATTCATGT
  AAATGGTGGCAGAAATACCAGAAGAGAAAGTTTCACTGTGCAAATCTAACATCATGGCCTCGCTGGCTGT
  ATTCATTATATGATGCTGAAACATTAATGGATAGAATTAAGAAACAGCTACGTGAATGGGATGAAAATCT
  CAAAGATGATTCTCTTCCTGAAAATCCAATAGACTTTTCTTACAGAGTAGCTGCTTGTCTTCCTATTGAT
  GATGTATTGAGAATTCAGCTCCTTAAAATCGGCAGTGCTATTCAACGGCTTCGCTGTGAATTGGACATCA
  TGAACAAATGTACTTCCCTTTGCTGTAAACAATGTCAAGAAACAGAAATAACGACAAAGAATGAAATATT
  TAGTTTATCCTTATGTGGTCCAATGGCAGCATATGTGAATCCTCATGGATATGTACATGAGACACTGACT
  GTGTATAAAGCGTCCAACCTGAATCTGATAGGCCGGCCTTCTACAGTGCACAGCTGGTTTCCCGGGTATG
  CATGGACCATTGCCCAGTGCAAGATCTGTGCAAGCCATATTGGATGGAAATTTACAGCCACAAAAAAAGA
  CATGTCACCTCAAAAATTTTGGGGCTTAACTCGCTCTGCTCTGTTACCCACAATTCCAGAGACTGAAGAT
  GAAATAAGTCCAGACAAAGTAATACTTTGTTTATAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCTGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: BC086488
• ORF Size: 1296 bp
• Insert Size: 1296
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC086488, AAH86488
• RefSeq Size: 2107
• RefSeq ORF: 1295
• Locus ID: 58799
• Gene Summary: This gene encodes a protein with a Lon protease domain, a "regulators of G protein-signaling" (RGS)-like domain and a leucine zipper. It has been proposed to regulate the assembly and surface expression of large-conductance calcium-activated potassium channels in brain and to bind thalidomide. In humans mutation in this gene causes autosomal recessive nonsyndromic cognitive disability. In mouse deficiency of this gene serves as a model to study the molecular mechanisms governing learning and memory as they relate to intellectual disability. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jan 2013]