Ltk (NM_008523) Mouse Untagged Clone

CAT#: MC219165

Ltk (untagged) - Mouse leukocyte tyrosine kinase (Ltk), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Ltk
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC219165 representing NM_008523
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  CTGGAGACCCGCGCGGCGGCGCCGGGCAGCGGCGGGAGAGGAGGCGCGGCAGGCGGTGATACTTCTGAGT
  CTGACCTCCTCTGGGCTGATGGGGAAGATGGCACATCCTTTGTCCACCCCAGTGGTGAGCTCTACCTACA
  GCCTCTGGCAGTCACAGAGGGCCATGGGGAGGTGGAGATCCGAAAGCATCCCAACTGCAGTCACTGCCCT
  TTCAAAGACTGCCAGTGGCAGGCAGAGCTCTGGACGGCCGAATGCACGTGCCCAGAGGGCACGGAGCTAG
  CTGTGGATAATGTCACTTGCATGGACCTGCCAACCACCGCAAGCCCTCTGATCCTGATGGGAGCTGTAGT
  GGCAGCCTTGGCACTGAGTCTCCTAATGATGTGTGCAGTCCTGATTCTAGTGAACCAGAAGTGTCAGGGC
  CTGTGGGGGACCAGGCTGCCAGGCCCTGAGCTTGAGCTAAGCAAGCTTCGATCCTCTGCCATCAGGACAG
  CACCCAACCCTTACTATTGTCAGGTGGGACTCAGTCCTGCCCAGCCCTGGCCTTTGCCCCCAGGGCTCAC
  TGAGGTTTCACCAGCCAATGTCACTCTACTCAGAGCCCTTGGCCATGGTGCCTTTGGGGAAGTGTACGAG
  GGACTAGTGACTGGTCTTCCTGGGGACTCCAGTCCTCTTCCAGTGGCTATTAAGACTCTGCCAGAGCTCT
  GCTCCCATCAGGATGAGCTGGATTTTCTCATGGAGGCTCTGATCATCAGCAAGTTCAGCCATCAGAACAT
  TGTACGCTGTGTGGGGCTCAGCTTTCGGTCTGCCCCGCGCCTCATTCTGCTGGAGCTGATGTCTGGTGGG
  GACATGAAGAGCTTTTTGAGGCACAGCAGACCACACCCAGGACAACTGGCACCTCTGACCATGCAGGACC
  TATTGCAGCTGGCCCAGGATATAGCCCAGGGCTGCCACTACCTGGAGGAAAATCACTTCATTCACAGAGA
  CATTGCTGCCCGTAACTGTCTGCTTAGCTGCAGTGGAGCCAGCCGAGTGGCCAAGATTGGAGATTTTGGA
  ATGGCAAGAGATATCTACCAGGCCAGTTATTATCGCAAGGGTGGCCGGACCTTGCTCCCAGTCAAGTGGA
  TGCCGCCAGAAGCTCTCCTGGAGGGCCTTTTCACATCCAAGACAGACTCCTGGTCTTTTGGGGTCCTGCT
  CTGGGAGATCTTCTCACTGGGGTATATGCCCTACCCTGGACATACCAACCAGGAGGTTCTAGACTTCATT
  GCCACAGGGAACAGGATGGACCCTCCTAGGAACTGTCCTGGGCCAGTGTACCGAATCATGACCCAGTGTT
  GGCAGCATCAGCCGGAGCTCCGCCCTGACTTTGGCAGCATCTTGGAACGGATTCAGTACTGCACTCAGGA
  CCCTGATGTGCTGAACTCACCCCTGCCCGTGGAACCTGGGCCCATTCTAGAGGAGGAAGAGGCCTCCAGG
  CTGGGAAACAGGTCACTGGAGGGTCTTAGATCCCCAAAGCCCCTAGAGCTGAGTTCTCAGAACTTGAAGA
  GCTGGGGAGGAGGCCTTCTTGGCTCTTGGCTGCCCTCTGGCCTCAAGACCCTCAAACCCAGGTGCCTCCA
  ACCTCAGAACATTTGGAACCCCACCTATGGCTCCTGGACCCCAAGGGGCCCCCAGGGTGAAGATACAGGC
  ATTGAACACTGCAATGGCTCCTCCTCAAGTTCCATTCCAGGCATCCAGTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_008523
• ORF Size: 1731 bp
• Insert Size: 1731
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_008523.2, NP_032549.2
• RefSeq Size: 2269
• RefSeq ORF: 1731
• Locus ID: 17005
• Gene Summary: The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. Four alternatively spliced transcript variants encoding different isoforms have been described for this gene. These transcripts are expressed in a tissue-specific manner in lymphocytes, brain and neuroblastoma cells, and the encoded isoforms exhibit different subcellular localization. The lymphocyte and brain specific variants initiate translation at non-AUG (CUG) start codons. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) is lacking several exons from the 5' end, and an internal coding exon compared to transcript variant 4. This results in a shorter isoform (A), which has a different N-terminus, is missing a 61 aa segment compared to isoform D, and that is localized in the endoplasmic reticulum. This variant is specifically expressed in the lymphocytes and initiates translation from a non-AUG (CUG) start codon.