Prkch (NM_008856) Mouse Untagged Clone

CAT#: MC220401

Prkch (untagged) - Mouse protein kinase C, eta (Prkch), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Prkch
• Synonyms: Pkch
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC220401 representing NM_008856
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTCGTCCGGCACGATGAAGTTCAATGGCTATCTGAGGGTCCGCATCGGAGAGGCTGTAGGGCTGCAGC
  CCACCCGCTGGTCCCTGCGGCACTCGCTCTTCAAAAAGGGCCACCAGCTGCTGGACCCCTACCTGACGGT
  GAGCGTAGACCAGGTACGCGTGGGCCAGACCAGCACAAAGCAGAAGACCAACAAACCCACCTACAACGAG
  GAGTTCTGCGCCAATGTCACCGACGGCGGCCACCTGGAGCTAGCCGTCTTCCACGAGACGCCCCTGGGTT
  ATGACCACTTTGTGGCCAACTGCACGCTGCAGTTCCAGGAGCTGTTGCGCACGGCTGGTACCTCGGACAC
  CTTCGAGGGCTGGGTGGATCTGGAGCCTGAGGGGAAAGTGTTTGTGGTAATAACCCTAACAGGGAGTTTC
  ACTGAAGCCACTCTCCAGAGAGACCGCATCTTCAAGCATTTTACCAGGAAGCGCCAAAGGGCTATGCGAA
  GACGAGTCCATCAAGTGAACGGACATAAGTTCATGGCCACGTACCTGAGGCAGCCCACCTACTGCTCTCA
  TTGCCGAGAGTTCATCTGGGGAGTATTTGGGAAACAGGGTTATCAATGCCAAGTGTGCACCTGCGTCGTC
  CATAAACGCTGCCATCATCTAATTGTTACAGCCTGCACTTGCCAAAACAATATTAACAAAGTGGATGCCA
  AGATTGCAGAACAGCGGTTTGGCATCAACATCCCACACAAGTTCAACGTTCACAATTACAAGGTGCCCAC
  GTTCTGTGACCACTGTGGCTCCCTGCTCTGGGGGATAATGCGACAAGGACTTCAGTGTAAAATATGTAAG
  ATGAATGTACATATTCGGTGTCAGGCGAACGTGGCCCCAAACTGCGGGGTGAATGCCGTGGAGCTTGCCA
  AGACCCTGGCAGGGATGGGTCTCCAACCCGGAAATATTTCTCCAACCTCGAAACTCATTTCCAGGTCGAC
  ACTAAGACGGCAGGGAAAGGAGGGCTCCAAAGAAGGAAATGGGATCGGTGTTAACTCTTCCAGCAGATTC
  GGCATCGACAACTTTGAGTTCATCCGGGTGTTGGGGAAGGGGAGCTTCGGGAAGGTGATGCTTGCCAGGA
  TAAAGGAGACAGGAGAACTGTACGCCGTGAAGGTGCTGAAGAAGGACGTGATTCTGCAGGATGATGATGT
  AGAGTGCACCATGACTGAGAAGAGGATCCTGTCCTTGGCCCGCAACCACCCCTTCCTCACCCAGCTCTTC
  TGCTGCTTTCAGACTCCAGACCGTCTGTTCTTTGTCATGGAGTTTGTGAACGGAGGCGACCTGATGTTCC
  ACATCCAAAAGTCCCGTCGTTTCGATGAAGCCCGTGCTCGTTTCTACGCCGCGGAGATCATTTCTGCACT
  CATGTTCCTACATGAGAAAGGTATCATCTATAGAGACTTGAAACTGGACAATGTGCTATTGGACCACGAA
  GGTCACTGTAAACTGGCCGACTTTGGAATGTGCAAGGAGGGGATTTGTAATGGGGTCACCACAGCCACCT
  TCTGCGGTACACCCGACTACATTGCCCCGGAGATCCTTCAGGAGATGCTGTATGGACCTGCAGTAGACTG
  GTGGGCCATGGGTGTGTTGCTTTATGAGATGCTGTGCGGACATGCGCCCTTTGAGGCTGAAAATGAAGAT
  GACCTTTTTGAGGCCATACTGAATGATGAAGTCGTCTACCCCACCTGGCTCCACGAAGATGCCACAGGGA
  TCCTCAAGTCTTTCATGACCAAGAACCCCACCATGCGCTTGGGCAGCCTGACTCAGGGAGGAGAGCATGA
  GATCCTGAGACACCCTTTCTTTAAGGAAATCGACTGGGCCCAGTTGAACCATCGCCAGTTAGAGCCGCCT
  TTCCGACCTAGAATCAAATCCCGAGAAGATGTCAGCAATTTTGACCCAGACTTTATAAAAGAAGAGCCCG
  TCTTAACTCCGATTGATGAGGGACATCTTCCTATGATTAACCAGGATGAGTTTAGAAACTTTTCCTATGT
  GTCACCGGAATTGCAACTGTAG
  
  AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC
  TGGATTACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-RsrII
• ACCN: NM_008856
• ORF Size: 2052 bp
• Insert Size: 2052
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_008856.4, NP_032882.2
• RefSeq Size: 3546
• RefSeq ORF: 2052
• Locus ID: 18755
• Gene Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene. Mutations in the human gene are associated with susceptibility to cerebral infarction. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
  Transcript Variant: This variant (1) encodes the longer isoform (1).