Ptpre (NM_011212) Mouse Untagged Clone

CAT#: MC220576

Ptpre (untagged) - Mouse protein tyrosine phosphatase, receptor type, E (Ptpre), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Ptpre
• Synonyms: PTPe; PTPepsilon; RPTPepsilon
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC220576 representing NM_011212
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGCCCTTCTGTCCACTCCTGCTGGCAAGTTTTAGCTTGTCGCTCGCCAGAGCTGGCCAGGGCAACG
  ACACCACCCCAACAGAGAGCAACTGGACCAGCACAACTGCAGGCCCTCCGGACCCTGGTGCATCCCAGCC
  GCTGCTCACCTGGCTGCTGCTGCCCCTGCTCCTCCTCCTGTTCCTGCTTGCAGCCTACTTCTTCAGGTTC
  CGGAAGCAGAGGAAGGCCGTGGTCAGCAGCAACGACAAGAAAATGCCTAACGGGATCTTAGAAGAGCAAG
  AGCAGCAGAGAGTGATGCTGCTGAGCAGATCTCCATCAGGCCCCAAGAAGTTCTTCCCCATCCCCGTGGA
  GCACCTGGAGGAGGAGATCCGGGTGAGATCTGCGGATGACTGCAAGCGATTCCGAGAGGAGTTCAATTCA
  TTGCCATCTGGACACATACAAGGAACCTTTGAACTAGCAAATAAAGAAGAAAACAGAGAAAAAAACAGAT
  ACCCCAACATTCTGCCCAATGATCATTGCAGAGTGATTTTGAGCCAAGTGGATGGAATCCCCTGCTCTGA
  CTACATTAATGCTTCCTACATCGATGGCTACAAAGAAAAGAACAAATTCATAGCAGCTCAAGGCCCTAAG
  CAGGAGACAGTGAATGACTTCTGGAGAATGGTCTGGGAGCAAAGGTCAGCCACCATCGTCATGTTGACGA
  ACCTGAAGGAGAGGAAGGAGGAGAAGTGCTACCAGTACTGGCCAGACCAGGGCTGTTGGACCTACGGCAA
  CATCCGGGTGTGTGTAGAGGACTGCGTGGTCCTGGTGGATTACACGATCCGAAAGTTCTGCATCCATCCG
  CAACTCCCAGACAGCTGCAAAGCCCCGCGGCTGGTCTCACAGCTGCACTTCACCAGCTGGCCTGACTTCG
  GGGTGCCGTTTACCCCCATCGGGATGCTCAAGTTCCTGAAGAAAGTGAAGACACTCAACCCCTCACATGC
  TGGGCCCATTGTGGTTCACTGTAGCGCGGGCGTGGGTCGGACTGGCACCTTCATTGTGATCGATGCCATG
  ATGGACATGATACACTCGGAGCAGAAGGTTGACGTCTTTGAGTTTGTGTCTAGAATCCGCAATCAGCGCC
  CTCAGATGGTCCAGACGGATGTTCAGTATACATTCATCTACCAAGCCTTACTGGAATACTACCTCTATGG
  GGACACAGAGCTGGATGTGTCCTCCCTGGAGAGGCACCTGCAGACGCTCCATAGCACAGCCACCCATTTT
  GACAAGATCGGGCTGGAGGAAGAGTTCAGGAAGCTGACCAACGTGCGAATCATGAAGGAGAACATGAGGA
  CGGGCAACCTGCCTGCCAACATGAAGAAGGCCCGCGTCATCCAGATCATTCCATATGACTTCAATCGGGT
  CATCCTGTCCATGAAAAGAGGGCAAGAGTTCACAGACTATATCAACGCATCCTTCATAGATGGCTACAGG
  CAGAAGGACTACTTCATGGCCACACAGGGGCCTCTGGCTCACACAGTTGAGGACTTCTGGAGGATGGTAT
  GGGAGTGGAAGTCTCACACAATCGTCATGCTGACGGAGGTGCAGGAGCGGGAACAGGATAAATGCTACCA
  GTATTGGCCAACGGAGGGCTCGGTGACTCATGGAGATATAACTATAGAGATAAAGAGCGACACCCTGTCT
  GAAGCAATCAGCGTACGAGACTTTCTGGTTACCTTCAAACAGCCCCTGGCCCGCCAGGAAGAGCAGGTCC
  GCATGGTGAGACAATTCCATTTCCATGGCTGGCCTGAGGTTGGCATCCCCGCTGAAGGCAAAGGCATGAT
  TGACCTGATTGCAGCAGTGCAGAAGCAGCAGCAGCAGACGGGCAACCACCCCATCACCGTGCACTGCAGC
  GCGGGAGCAGGGCGGACAGGTACATTCATAGCACTCAGTAACATTTTGGAACGAGTGAAAGCCGAGGGAC
  TCCTAGACGTGTTTCAAGCTGTGAAGAGCTTAAGACTTCAGAGACCACACATGGTGCAGACCCTGGAGCA
  ATATGAATTCTGCTACAAAGTGGTACAAGATTTTATCGATATATTTTCTGATTATGCTAATTTCAAATGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_011212
• ORF Size: 2100 bp
• Insert Size: 2100
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_011212.3, NP_035342.3
• RefSeq Size: 5411
• RefSeq ORF: 2100
• Locus ID: 19267
• Gene Summary: Isoform 1 and isoform 2 act as a negative regulator of FceRI-mediated signal transduction leading to cytokine production and degranulation, most likely by acting at the level of SYK to affect downstream events such as phosphorylation of SLP76 and LAT and mobilization of Ca(2+). [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) contains an alternate exon in the 5' end compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Variants 2 and 3 both encode the same isoform (b). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.