Suz12 (NM_001163018) Mouse Untagged Clone

CAT#: MC221005

Suz12 (untagged) - Mouse suppressor of zeste 12 homolog (Drosophila) (Suz12), transcript variant 2, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Suz12
• Synonyms: 2610028O16Rik; AI195385; AU016842; AW536442; D11Ertd530e; mKIAA0160
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC221005 representing NM_001163018
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCGCCTCAGAAGCACGGCGGTGGGGGAGGGGGCGGCTCGGGGCCCAGCGCGGGGTCCGGGGGAGGCG
  GCTTCGGGGGTTCGGCGGCGGCGGTGGCGGCGGCGGCTTCGGGCGGCAAATCCGGCGGCGGGGGCTGTGG
  AGGCGGCGGCAGTTACTCGGCCTCCTCCTCCTCGGCGGCGGCCGCGGCGGCGGCGGCGGGGGCCGCGGTG
  TTGCCGGTGAAGAAGCCGAAAATGGAGCACGTCCAGGCTGACCACGAGCTTTTCCTCCAGGCCTTTGAGA
  AACCAACACAGATATATAGATTTCTTCGAACTCGAAATCTTATCGCACCAATATTTTTGCACAGAACTCT
  TACTTACATGTCTCATCGAAATTCCAGAACAAGCATCAAAAGCTTGTCTGCACATTTGCAACTTACATTT
  ACCGGTTTCTTCCACAAAAATGATAAGCCATCACAAAACTCAGAAAATGAACAAAATTCTGTTACCCTGG
  AAGTCCTGCTTGTGAAAGTTTGCCACAAAAAAAGGAAGGATGTAAGTTGTCCAATAAGACAAGTCCCTAC
  TGGTAAAAAGCAGGTGCCTTTGAATCCTGACCTCAATCAAACAAAACCAGGAAATTTTCCATCCCTGGCA
  GTTTCCAGTAATGAATTTGAACCTAGTAACAGCCATATGGTGAAGTCCTACTCGTTGCTGTTTAGAGTAA
  CTCGTCCAGGAAGAAGAGAATTTAATGGAATGATTAATGGAGAAACCAATGAAAATATTGATGTCAGTGA
  AGAACTTCCAGCCAGAAGAAAACGAAATCGCGAAGATGGAGAAAAGACATTTGTTGCACAAATGACAGTT
  TTTGACAAAAACAGGCGTTTACAGCTTTTAGATGGGGAATATGAAGTGGCCATGCAGGAAATGGAAGAAT
  GTCCAATAAGTAAGAAAAGAGCAACATGGGAGACAATTCTTGATGGGAAGAGGCTGCCTCCATTTGAGAC
  ATTTTCTCAGGGACCTACATTACAATTTACTCTTCGATGGACAGGAGAAACCAACGATAAGTCTACAGCT
  CCTGTTGCCAAGCCTCTTGCCACTAGAAATTCAGAGAGCCTTCATCAGGAAAATAAGCCTGGTTCTGTTA
  AACCTGCACAAACTATTGCTGTTAAGGAGACGCTGACTACAGAGCTGCAAACAAGAAAAGAAAAGGATAA
  TTCAAATGAAAGTCGCCAGAAGTTAAGAATATTTTATCAGTTCCTTTATAACAATAATACAAGACAACAG
  ACAGAAGCCAGAGACGACCTGCACTGCCCGTGGTGCACTCTGAACTGCCGTAAACTGTATAGCTTACTCA
  AACATCTAAAGCTCTGCCACAGCAGGTTCATCTTCAATTACGTATATCATCCAAAAGGTGCTAGGATAGA
  TGTTTCAATCAATGAGTGTTATGATGGCTCCTATGCAGGAAATCCTCAGGATATACATCGCCAACCTGGA
  TTTGCTTTTAGTCGAAATGGACCGGTAAAGAGAACACCTATCACACATATTCTTGTTTGCAGGCCAAAAA
  GAACAAAAGCAAGCATGTCGGAGTTTCTTGAATCTGAAGATGGAGAAGTGGAGCAGCAGAGAACATACAG
  CAGTGGCCACAATCGTCTCTATTTCCACAGTGATACCTGCTTACCTCTTCGGCCACAAGAAATGGAAGTA
  GATAGTGAAGATGAGAAAGATCCAGAATGGCTGAGAGAAAAAACCATTACTCAAATTGAAGAATTTTCTG
  ATGTGAATGAAGGAGAGAAAGAAGTGATGAAGCTGTGGAACCTCCATGTCATGAAGCATGGATTTATTGC
  TGACAATCAAATGAATCATGCCTGTATGCTGTTTGTAGAAAATTATGGACAGAAAATAATTAAGAAGAAT
  TTATGTCGAAACTTCATGCTTCATCTAGTCAGCATGCATGACTTTAATCTTATTAGCATAATGTCAATAG
  ATAAAGCTGTTACCAAGCTCCGAGAAATGCAGCAAAAACTAGAAAAAGGAGAATCTGCGACCCCTTCAAA
  TGAAGAAATAGCTGAGGAACAAAATGGAACAGCAAATGGATTCAGTGAAACTAACTCAAAAGAGAAAGCT
  TTGGAAACTGACGGTGTCTCAGGGGTTCCAAAACAGAGCAAGAAACAAAAACTCTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001163018
• ORF Size: 2157 bp
• Insert Size: 2157
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001163018.1, NP_001156490.1
• RefSeq Size: 4380
• RefSeq ORF: 2157
• Locus ID: 52615
• Gene Summary: This gene encodes a core component of the polycomb repressive complex 2 (PRC2) that also includes, at least, embryonic ectoderm development protein (EED) and enhancer of zeste homolog 1 or 2 (EZH1 or EZH2). Through the methyltransferase activity of EZH1 or EZH2, the PRC2 complex methylates Lys9 and Lys27 of histone 3 and Lys26 of histone 1, leading to recruitment of the PRC1 complex, histone 2A ubiquitylation and transcriptional repression of the target genes. This gene product is essential for the activity and integrity of the PRC2 complex, and is required for X chromosome inactivation, stem cell maintenance and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]
  Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter compared to isoform 1.