Abcd1 (NM_007435) Mouse Untagged Clone

CAT#: MC221143

Abcd1 (untagged) - Mouse ATP-binding cassette, sub-family D (ALD), member 1 (Abcd1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Abcd1
• Synonyms: Ald; Aldgh; ALDP
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC221143 representing NM_007435
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCGGTGCTCTCCACTCCCCGGCCCTCACGGGTGACCACGCTGAAGCGCACAGCTGTGGTCCTGGCCC
  TCACAGCCTATGGAGTCCACAAAATCTACCCTCTAGTACGGCAGTGTCTGACTCCTGCCAGAGGTCCTCA
  GGTGCCAGCTGGGGAGCCCACTCAAGAGGCCTCTGGAGCCACCGCAACCAAGGCTGGCATGAACCGGGTA
  TTCCTGCAGCGGCTCTTGGCGCTCCTGAGGCTGCTGTTCCCCCGAGTCTTGTGCCGGGAAACAGGGCTGC
  TGGCCCTGCATTCTGCTGCCCTGGTAAGCCGAACTTTCCTGTCTGTGTATGTTGCCCGCCTGGACGGCAG
  ACTGGCCCGCTGCATTGTACGTAAGGACCCGCGGGCCTTTAGCTGGCAACTGCTGCAGTGGCTCCTCATC
  GCCCTTCCTGCCACTTTCATCAACAGTGCCATCCGCTACCTAGAGGGCCAGCTGGCTCTTTCTTTCCGAA
  GCCGTCTAGTAGCTCATGCCTATGGACTCTACTTCTCCCAACAGACTTACTACCGAGTAAGCAACATGGA
  TGGACGACTTCGAAACCCTGATCAGTCTCTGACAGAGGATGTGGTAGCCTTTGCTGCCTCTGTAGCCCAC
  CTTTATTCCAACCTGACCAAGCCACTCCTGGATGTGGCTGTGACCTCCTACACTCTCCTTCGAGCTGCCC
  GATCCCGAGGAGCTGGCACAGCCTGGCCCTCAGCCATCGCTGGCCTGGTGGTGTTCCTCACAGCCAACGT
  GCTTCGAGCCTTCTCTCCCAAGTTTGGGGAGCTAGTGGCAGAGGAGGCACGGCGAAAGGGGGAACTGCGC
  TACATGCACTCTCGAGTGGTGGCCAACTCAGAGGAAATTGCCTTCTACGGGGGCCATGAGGTGGAACTGG
  CACTACTACAGCACTCCTATCAAGACCTAGCTTCACAGATCAACCTCATCCTGCTTGAGCGCCTATGGTA
  TGTCATGCTGGAACAGTTCCTCATGAAATATGTGTGGAGTGCATCTGGCCTGCTCATGGTAGCTGTCCCC
  ATCATCACAGCCACTGGCTATGCAGAGTCAGACTCAGAAGCCATGAAGAAGGCAGCCTTGGAAATGAAGG
  AAGAGGAGCTGGTTAGTGAGCGTACAGAAGCTTTCACCATTGCCCGAAACCTCCTCACAGCTGCTGCAGA
  TGCCACCGAAAGGATCATGTCATCTTATAAGGAGGTGACAGAGCTGGCTGGCTACACAGCCAGGGTGTAC
  GAGATGTTCCAGGTATTTGAAGATGTCAAACACTGTCGTTTTAAGAGGACAGGAGATCTAGAGGAGGCTC
  AGGCTGGGCCTGGGGTCATGGTACAGTCTGGTGTCCATGTAGAGGGGCCCCTGAAGATCCAAGGCCAAGT
  TGTGGATGTGGAGCAGGGGATCATCTGTGAGAACATCCCTATCATCACACCCACTGGAGAGGTGGTGGTG
  GCCAGCCTCAACATCAGGGTGGAGGAAGGCATGCACCTGCTCATCACAGGCCCCAATGGCTGTGGCAAGA
  GTTCTCTGTTCCGAATCCTAGGTGGACTCTGGCCCACATACAGTGGTGTACTCTATAAGCCCCCACCCCA
  GCGCATGTTCTATATCCCTCAGAGGCCCTACATGTCCGTGGGCTCCTTGCGTGACCAAGTGATCTATCCC
  GACTCTGCGGAAGACATGCGGAGGAAGGGCTGCTCGGAGCAGCAGCTGGAAGCAATCCTGGGCATCGTGC
  ATCTCCGCCACATCCTGCAACGGGAGGGAGGTTGGGAGGCAGTGTGTGACTGGAAGGACGTCCTGTCTGG
  AGGTGAGAAGCAGAGGATTGGTATGGCGCGCATGTTCTACCACAGGCCCAAGTACGCCCTCCTGGATGAG
  TGCACTAGTGCCGTGAGCATTGATGTGGAAGGCAAGATCTTCCAAGCAGCCAAAGATGCTGGTATCGCAC
  TGCTCTCCATCACCCATCGACCCTCCCTATGGAAGTACCACACACACTTGCTGCAGTTTGATGGGGAAGG
  AGGCTGGAAGTTTGAGAAGCTGGATTCTGCTGCCCGCCTGAGCCTGACTGAAGAGAAGCAGCGCCTGGAG
  CAGCAACTGGCGGGCATCCCCAAGATGCAGGGGCGCCTTCAGGAGCTCCGCCAGATCCTTGGCGAAGCTG
  CAGCTCCAGTTCAACCCCTGGTCCCAGGAGTCCCCACTTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_007435
• ORF Size: 2211 bp
• Insert Size: 2211
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_007435.2, NP_031461.1
• RefSeq Size: 3664
• RefSeq ORF: 2211
• Locus ID: 11666
• Gene Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in the human gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system. [provided by RefSeq, Jul 2008]