F13a1 (NM_028784) Mouse Untagged Clone

CAT#: MC221176

F13a1 (untagged) - Mouse coagulation factor XIII, A1 subunit (F13a1), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: F13a1
• Synonyms: 1200014I03Rik; AI462306; F13a
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC221176 representing NM_028784
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTCAGATACTCCAGCAAGCACCTTTGGGGGGAGGCGAGCAGTCCCGCCCAATAACTCCAATGCTGCAG
  AAGTGGACCTCCCAACTGAGGAGCTACAAGGCCTGGTGCCAAGGGGTGTCAACCTGAAAGATTACCTGAA
  TGTCACAGCTGTTCACCTGTTCAAGGAGAGATGGGACAGTAACAAGATTGATCACCACACAGACAAATAT
  GACAACAATAAGTTGATTGTCCGCAGAGGGCAGACCTTCTACATCCAGATTGACTTCAACCGTCCCTATG
  ACCCCAGGAAGGATCTCTTCAGAGTGGAATATGTCATTGGTCGCTACCCTCAGGAGAACAAGGGCACCTA
  CATCCCTGTGCCTGTAGTGAAAGAGCTGCAAAGCGGAAAGTGGGGAGCCAAGGTTATCATGAATGAGGAC
  CGGTCGGTGCGACTTTCCGTTCAGTCTTCTCCGGAATGCATTGTGGGGAAATTCCGCATGTATGTTGCAG
  TCTGGACTCCCTATGGCATCCTGCGTACTCGAAGAGACCCAGAAACAGACACATATATTCTCTTCAACCC
  TTGGTGTGAAGAGGACGCTGTGTATCTGGATGATGAGAAGGAAAGAGAAGAGTACGTCCTGAATGACATT
  GGAGTGATATTTTATGGGGACTTCAAAGACATCAAGAGCAGAAGCTGGAGCTATGGCCAGTTCGAAGACG
  GCATCCTGGATACTTGCTTGTATGTGATGGACAAAGCTGAGATGGACCTTTCTGGCAGAGGCAACCCCAT
  CAAAGTCAGCCGAGTTGGATCAGCAATGGTGAATGCCAAGGATGATGAAGGTGTTCTTGTTGGATCATGG
  GACAATGTCTATGCCTACGGCATCCCTCCATCAGCCTGGACAGGAAGTGTTGACATTCTACTAGAATACA
  GAAGCTCGGAAACACCAGTCCGATATGGCCAGTGTTGGGTTTTTGCTGGTGTCTTTAACACATTTTTAAG
  ATGCCTTGGAATCCCTGCACGAGTCATTACCAATTACTTCTCGGCCCACGACAATGATGCCAATCTGCAA
  ATGGACATCTTCCTGGAAGAAGATGGGAATGTGAGCTCCAAACTCACCAAGGATTCGGTGTGGAACTACC
  ACTGCTGGAACGAAGCGTGGATGACAAGGCCTGATCTTCCTGTTGGATTTGGAGGCTGGCAAGCTGTGGA
  CAGCACACCCCAGGAAAACAGTGATGGCATGTACCGCTGTGGCCCTGCCTCTGTCCAAGCCGTTAAGCAT
  GGCCATGTCTGCTTCCAGTTTGATGCCCCGTTTGTTTTTGCAGAGGTCAACAGTGATCTTGTTTACATCA
  CAGCTAAGCAAGATGGCACTCACGTGGTGGAAGCCGTGGATGCCACCCATATCGGGAAGCTAATTGTGAC
  CAAGCAAATTGGAGGAGATGGCATGCAGGATATCACGGATACTTACAAATTTCAAGAAGGCCAAGAAGAA
  GAGAGACTAGCCCTTGAAACTGCTCTGATGTATGGAGCCAAGAAGACCCTCAACACTGAAGGTGTTGTCA
  AATCAAGGTCTGATGTGACCATGAACTTTGATGTGGAAAATGCTGTGCTGGGAAAGGACTTCAAAGTGAC
  TATCACCTTCCAGAACAATAGCTCCAATCTGTACACCATCCTGGCCTATCTTTCTGGCAACATCACCTTC
  TACACTGGGGTATCCAAGAAAGAGTTCAAGAAGGAGTCCTTTGAAGAGACGCTGGATCCCTTTTCCTCCA
  AGAAAAAGGAGGTGCTGGTCAGAGCGGGCGAGTACATGAGCCACCTTCTAGAACAGGGCTTCTTGCACTT
  CTTCGTCACGGCACGCATCAACGAGTCCAGGGATGTCCTGGCCAAACAAAAGTCCATAATACTGACTATC
  CCCAAGATCACCATCAAGGTCCGAGGTGCTGCCATGGTTGGCTCTGATATGGTTGTGACTGTTGAGTTCA
  CTAATCCTTTAAAAGAAACACTACAAAATGTCTGGATTCATTTGGATGGTCCTGGAGTGATGAGACCCAA
  GAGAAAGGTGTTCCGTGAAATCCGGCCCAACACCACGGTGCAGTGGGAAGAAGTCTGTCGGCCTTGGGTC
  TCTGGCCATCGGAAGCTGATTGCCAGCATGACCAGTGACTCCCTGAGACATGTGTATGGAGAGCTGGATC
  TTCAGATTCAAAGACGACCTACTATGTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_028784
• ORF Size: 2199 bp
• Insert Size: 2199
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_028784.3, NP_083060.2
• RefSeq Size: 3879
• RefSeq ORF: 2199
• Locus ID: 74145
• Gene Summary: This gene encodes subunit A of the coagulation factor XIII that catalyzes the final step of the blood coagulation pathway. The encoded protein associates with subunit B to form a heterotetrameric proenzyme that undergoes thrombin-mediated proteolysis to generate active factor XIIIa. The transglutaminase activity of factor XIIIa is required for the calcium-dependent crosslinking of fibrin, leading to the formation of a clot. Mice lacking the encoded protein display impaired reproduction and reduced survival due to bleeding episodes, hematothorax, hematoperitoneum and subcutaneous hemorrhage. Additionally, mice lacking the encoded protein exhibit impaired wound healing and inadequate healing of myocardial infarction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
  Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.