Il12rb1 (NM_008353) Mouse Untagged Clone

CAT#: MC221222

Il12rb1 (untagged) - Mouse interleukin 12 receptor, beta 1 (Il12rb1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Il12rb1
• Synonyms: CD212; IL-12R[b]
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC221222 representing NM_008353
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGACATGATGGGGCTGGCAGGGACCAGCAAACACATCACCTTCCTCCTGCTTTGCCAGCTAGGCGCCT
  CAGGCCCAGGTGATGGCTGCTGCGTTGAGAAGACATCGTTCCCAGAGGGAGCCTCAGGCTCACCCTTAGG
  ACCCAGGAACTTGAGTTGCTACAGGGTTTCCAAGACAGACTATGAGTGCTCCTGGCAGTATGATGGCCCT
  GAGGACAATGTTTCTCACGTCCTGTGGTGCTGCTTTGTCCCTCCGAACCATACCCACACCGGCCAGGAGC
  GCTGCCGCTACTTCTCCTCAGGCCCAGACCGCACTGTGCAGTTCTGGGAACAGGACGGTATCCCTGTGCT
  GTCCAAGGTCAACTTCTGGGTGGAGTCTCGGCTTGGGAACCGAACCATGAAGTCCCAGAAGATATCCCAG
  TACCTGTACAACTGGACCAAGACGACCCCTCCCCTGGGACACATCAAGGTGTCACAATCACACCGGCAGT
  TGCGAATGGACTGGAATGTGTCTGAAGAGGCCGGTGCTGAGGTACAGTTCAGGCGCCGTATGCCCACAAC
  GAATTGGACCTTGGGTGACTGCGGACCTCAGGTTAACTCTGGCTCAGGTGTGCTTGGTGACATTCGTGGG
  AGCATGTCTGAGTCCTGCCTCTGCCCTTCTGAGAACATGGCCCAAGAGATCCAGATACGGAGGAGGAGGC
  GGCTCTCCTCAGGAGCCCCTGGAGGTCCCTGGAGTGATTGGAGCATGCCTGTGTGTGTTCCACCTGAAGT
  CCTTCCCCAGGCCAAGATTAAGTTCTTGGTGGAGCCCCTGAACCAAGGTGGAAGGAGGCGTCTAACCATG
  CAAGGACAGTCACCACAGCTGGCAGTCCCGGAAGGCTGCCGAGGCAGGCCTGGTGCGCAGGTGAAGAAGC
  ACTTGGTGCTGGTGCGCATGCTGTCCTGCAGGTGCCAGGCTCAGACCTCGAAGACCGTGCCCCTGGGCAA
  GAAGCTGAACCTCTCCGGGGCCACCTATGACCTGAATGTGCTCGCCAAAACTCGTTTCGGTCGCAGCACC
  ATCCAGAAGTGGCACCTTCCTGCCCAAGAGCTCACAGAGACAAGAGCCCTGAATGTCAGCGTGGGAGGCA
  ACATGACATCCATGCAGTGGGCAGCCCAGGCTCCCGGCACCACCTACTGCCTTGAGTGGCAGCCATGGTT
  CCAGCACAGGAACCACACACACTGTACCCTGATTGTACCAGAAGAAGAGGATCCTGCCAAGATGGTGACA
  CACAGCTGGAGCTCTAAACCTACCCTGGAGCAGGAGGAATGTTACCGCATCACAGTGTTCGCCTCCAAGA
  ACCCCAAGAATCCCATGCTGTGGGCCACAGTCCTGTCCAGTTACTACTTTGGGGGTAACGCCTCGAGAGC
  CGGTACTCCACGACACGTGTCGGTGAGGAACCAAACCGGGGACTCGGTGTCCGTGGAGTGGACGGCGTCA
  CAGCTGAGCACCTGCCCGGGGGTCCTGACGCAATACGTCGTGCGCTGCGAGGCTGAAGACGGCGCGTGGG
  AGTCAGAGTGGCTCGTGCCACCCACTAAAACCCAAGTGACACTTGACGGACTGCGCAGCCGAGTAATGTA
  CAAGGTTCAGGTGCGAGCCGACACTGCGAGGCTCCCGGGTGCCTGGAGTCATCCCCAGCGCTTTAGCTTT
  GAGGTGCAGATTTCCCGTTTATCCATCATTTTCGCGTCTCTGGGAAGCTTCGCCAGCGTCCTCCTCGTGG
  GCAGTCTCGGATACATTGGCTTAAACAGGGCCGCCTGGCACTTGTGCCCACCCCTGCCTACACCCTGTGG
  CAGCACTGCCGTGGAGTTCCCTGGCAGCCAGGGCAAGCAGGCTTGGCAGTGGTGCAACCCTGAGGACTTC
  CCGGAGGTGTTGTACCCGCGAGATGCGCTGGTGGTCGAGATGCCCGGAGACAGAGGCGACGGGACAGAGT
  CGCCCCAGGCCGCCCCTGAGTGCGCCCTGGACACAAGGCGGCCCTTGGAGACTCAGAGGCAGAGGCAGGT
  GCAGGCACTGTCAGAGGCCAGGCGCCTGGGCCTGGCTAGGGAGGACTGTCCCCGTGGTGACCTGGCCCAC
  GTGACACTCCCGCTGCTCCTGGGAGGTGTGACCCAGGGAGCCTCTGTACTTGACGATCTTTGGAGGACCC
  ATAAGACTGCGGAGCCGGGACCGCCCACTTTGGGGCAAGAGGCCTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_008353
• ORF Size: 2217 bp
• Insert Size: 2217
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_008353.2, NP_032379.2
• RefSeq Size: 2873
• RefSeq ORF: 2217
• Locus ID: 16161
• Gene Summary: Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade. [UniProtKB/Swiss-Prot Function]