Stat3 (NM_213659) Mouse Untagged Clone

CAT#: MC221487

Stat3 (untagged) - Mouse signal transducer and activator of transcription 3 (Stat3), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Stat3
• Synonyms: 1110034C02Rik; Aprf; AW109958
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_213659, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCTCAGTGGAACCAGCTGCAGCAGCTGGACACACGCTACCTGGAGCAGCTGCACCAGCTGTACAGCG
  ACAGCTTCCCCATGGAGCTGCGGCAGTTCCTGGCACCTTGGATTGAGAGTCAAGACTGGGCATATGCAGC
  CAGCAAAGAGTCACATGCCACGTTGGTGTTTCATAATCTCTTGGGTGAAATTGACCAGCAATATAGCCGA
  TTCCTGCAAGAGTCCAATGTCCTCTATCAGCACAACCTTCGAAGAATCAAGCAGTTTCTGCAGAGCAGGT
  ATCTTGAGAAGCCAATGGAAATTGCCCGGATCGTGGCCCGATGCCTGTGGGAAGAGTCTCGCCTCCTCCA
  GACGGCAGCCACGGCAGCCCAGCAAGGGGGCCAGGCCAACCACCCAACAGCCGCCGTAGTGACAGAGAAG
  CAGCAGATGTTGGAGCAGCATCTTCAGGATGTCCGGAAGCGAGTGCAGGATCTAGAACAGAAAATGAAGG
  TGGTGGAGAACCTCCAGGACGACTTTGATTTCAACTACAAAACCCTCAAGAGCCAAGGAGACATGCAGGA
  TCTGAATGGAAACAACCAGTCTGTGACCAGACAGAAGATGCAGCAGCTGGAACAGATGCTCACAGCCCTG
  GACCAGATGCGGAGAAGCATTGTGAGTGAGCTGGCGGGGCTCTTGTCAGCAATGGAGTACGTGCAGAAGA
  CACTGACTGATGAAGAGCTGGCTGACTGGAAGAGGCGGCAGCAGATCGCGTGCATCGGAGGCCCTCCCAA
  CATCTGCCTGGACCGTCTGGAAAACTGGATAACTTCATTAGCAGAATCTCAACTTCAGACCCGCCAACAA
  ATTAAGAAACTGGAGGAGCTGCAGCAGAAAGTGTCCTACAAGGGCGACCCTATCGTGCAGCACCGGCCCA
  TGCTGGAGGAGAGGATCGTGGAGCTGTTCAGAAACTTAATGAAGAGTGCCTTCGTGGTGGAGCGGCAGCC
  CTGCATGCCCATGCACCCGGACCGGCCCTTAGTCATCAAGACTGGTGTCCAGTTTACCACGAAAGTCAGG
  TTGCTGGTCAAATTTCCTGAGTTGAATTATCAGCTTAAAATTAAAGTGTGCATTGATAAAGACTCTGGGG
  ATGTTGCTGCCCTCAGAGGGTCTCGGAAATTTAACATTCTGGGCACGAACACAAAAGTGATGAACATGGA
  GGAGTCTAACAACGGCAGCCTGTCTGCAGAGTTCAAGCACCTGACCCTTAGGGAGCAGAGATGTGGGAAT
  GGAGGCCGTGCCAATTGTGATGCCTCCTTGATCGTGACTGAGGAGCTGCACCTGATCACCTTCGAGACTG
  AGGTGTACCACCAAGGCCTCAAGATTGACCTAGAGACCCACTCCTTGCCAGTTGTGGTGATCTCCAACAT
  CTGTCAGATGCCAAATGCTTGGGCATCAATCCTGTGGTATAACATGCTGACCAATAACCCCAAGAACGTG
  AACTTCTTCACTAAGCCGCCAATTGGAACCTGGGACCAAGTGGCCGAGGTGCTCAGCTGGCAGTTCTCGT
  CCACCACCAAGCGGGGGCTGAGCATCGAGCAGCTGACAACGCTGGCTGAGAAGCTCCTAGGGCCTGGTGT
  GAACTACTCAGGGTGTCAGATCACATGGGCTAAATTCTGCAAAGAAAACATGGCTGGCAAGGGCTTCTCC
  TTCTGGGTCTGGCTAGACAATATCATCGACCTTGTGAAAAAGTATATCTTGGCCCTTTGGAATGAAGGGT
  ACATCATGGGTTTCATCAGCAAGGAGCGGGAGCGGGCCATCCTAAGCACAAAGCCCCCGGGCACCTTCCT
  ACTGCGCTTCAGCGAGAGCAGCAAAGAAGGAGGGGTCACTTTCACTTGGGTGGAAAAGGACATCAGTGGC
  AAGACCCAGATCCAGTCTGTAGAGCCATACACCAAGCAGCAGCTGAACAACATGTCATTTGCTGAAATCA
  TCATGGGCTATAAGATCATGGATGCGACCAACATCCTGGTGTCTCCACTTGTCTACCTCTACCCCGACAT
  TCCCAAGGAGGAGGCATTTGGAAAGTACTGTAGGCCCGAGAGCCAGGAGCACCCCGAAGCCGACCCAGGT
  AGTGCTGCCCCGTACCTGAAGACCAAGTTCATCTGTGTGACACCAACGACCTGCAGCAATACCATTGACC
  TGCCGATGTCCCCCCGCACTTTAGATTCATTGATGCAGTTTGGAAATAACGGTGAAGGTGCTGAGCCCTC
  AGCAGGAGGGCAGTTTGAGTCGCTCACGTTTGACATGGATCTGACCTCGGAGTGTGCTACCTCCCCCATG
  TGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_213659
• ORF Size: 2313 bp
• Insert Size: 2313
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: BC003806, AAH03806
• RefSeq Size: 2964
• RefSeq ORF: 2313
• Locus ID: 20848
• Gene Summary: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2015]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.