Msh5 (NM_001146215) Mouse Untagged Clone

CAT#: MC221932

Msh5 (untagged) - Mouse mutS homolog 5 (E. coli) (Msh5), transcript variant 2, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Msh5
• Synonyms: Mut5
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC221932 representing NM_001146215
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCTTTCAGAGCGACCCCAGGCCGGACGCCGCCGGGACCCGGACCCAGATCCGGAATCCCCTCAGCCA
  GCTTCCCCAGCCCTCAGCCCCCAATGGCGGGGCCTGGAGGTATCGAGGAAGAGGACGAGGAGGAGCCCGC
  CGAGATCCATCTGTGCGTGCTGTGGAGCTCGGGATACCTGGGCATTGCTTACTATGACACTAGTGACTCC
  ACTATCCACTTCATGCCAGATGCCCCAGACCACGAGAGCCTAAAGCTTCTCCAGAGAGTTCTGGATGAAA
  TCAACCCCCAGTCTGTTGTCACAAGTGCCAAACAGGATGAGGCTATGACTCGATTTCTAGGGAAGCTTGC
  CTCCGAGGAGCACAGAGAGCCAAAGGGACCTGAAATCATACTTCTGCCAAGCGTGGATTTTGGTCCAGAG
  ATAAGCAAACAGCGTCTCCTTTCCGGAAACTACTCCTTCATCTCAGACTCCATGACTGCTACTGAGAAAA
  TCCTTTTCCTCTCCTCCATTATTCCCTTTGACTGTGTCCTCACGGTCCGGGCACTTGGAGGACTGCTCAA
  GTTCCTGAGTCGAAGAAGAATTGGGGTTGAACTGGAAGACTATGATGTTGGCGTCCCTATCCTGGGATTC
  AAGAAGTTTGTATTGACCCATCTGGTGAGCATAGATCAAGACACTTACAGCGTTCTACAGATTTTCAAGA
  GTGAGTCTCACCCCTCGGTGTACAAAGTAGCCAGTGGGCTGAAGGAGGGGCTCAGCCTTTTTGGAATCCT
  CAACAGATGCCGCTGTAAGTGGGGACAGAAGCTGCTCAGGCTGTGGTTTACACGTCCAACCCGGGAGCTA
  AGGGAACTCAATTCCCGACTGGATGTCATTCAGTTCTTCCTGATGCCTCAGAACCTGGACATGGCCCAGA
  TGCTGCACCGACTCCTGAGCCACATCAAGAATGTGCCTCTGATTCTGAAACGCATGAAGTTGTCCCACAC
  CAAGGTCAGTGACTGGCAGGTCCTCTACAAGACTGTGTACAGTGCTCTCGGCCTGAGGGATGCCTGCCGT
  TCTCTGCCACAGTCCATCCAGCTTTTTCAGGACATTGCCCAGGAGTTCTCTGACGACCTGCATCACATTG
  CCAGCCTCATCGGGAAGGTGGTGGACTTTGAGGAAAGTCTTGCTGAAAATCGCTTCACAGTCCTCCCTAA
  CATAGACCCTGACATAGATGCCAAGAAGCGAAGGCTGATAGGGCTTCCGAGCTTCCTCACTGAAGTTGCT
  CAGAAGGAGCTGGAGAACCTGGACTCTCGCATCCCCTCATGCAGTGTCATCTACATCCCTCTGATTGGCT
  TCCTTCTTTCCATTCCCCGCTTGCCTTTCATGGTGGAAGCTAGTGACTTTGAGATTGAGGGGCTGGACTT
  CATGTTTCTCTCAGAGGACAAGCTGCACTATCGTAGCGCCCGGACCAAGGAGCTGGACACGCTGCTGGGA
  GACCTGCACTGCGAGATCCGGGACCAGGAGACCCTGTTGATGTACCAGCTGCAGTGCCAGGTGCTGGCAC
  GGGCTTCGGTCTTGACTCGGGTATTGGACCTTGCCTCCCGCCTGGACGTCCTGTTGGCTCTTGCCAGTGC
  TGCCCGGGACTACGGCTATTCGAGACCGCATTACTCTCCCTGTATCCATGGAGTACGAATCAGGAATGGC
  AGGCATCCTCTGATGGAACTGTGTGCACGAACCTTCGTGCCCAACTCCACGGACTGTGGTGGGGACCAGG
  GCAGGGTCAAAGTCATCACTGGGCCCAACTCCTCAGGGAAAAGCATATATCTCAAGCAGGTAGGCTTGAT
  CACTTTCATGGCCCTGGTGGGCAGTTTCGTGCCTGCAGAGGAGGCCGAGATTGGGGTAATCGACGCCATC
  TTCACTCGAATTCACAGCTGCGAATCCATCTCCCTCGGCCTCTCCACCTTCATGATTGATCTCAACCAGG
  TGGCGAAAGCAGTGAACAATGCCACAGAGCACTCGCTGGTCCTGATCGATGAATTCGGGAAGGGGACCAA
  CTCGGTGGATGGCCTGGCACTTCTGGCTGCTGTGCTCCGTCACTGGCTAGCACTGGGACCCAGCTGCCCC
  CACGTCTTTGTAGCCACCAACTTCCTGAGCCTTGTTCAGCTGCAGCTGCTGCCGCAAGGACCCCTGGTGC
  AGTATTTGACCATGGAGACTTGTGAGGATGGGGAAGACCTTGTCTTCTTCTACCAGCTTTGCCAAGGCGT
  CGCCAGTGCCAGCCACGCCTCCCACACAGCGGCCCAGGCTGGGCTTCCTGACCCACTCATTGCTCGTGGC
  AAAGAGGTCTCAGACTTGATCCGCAGTGGGAAACCCATCAAGGCCACGAATGAGCTTCTGAGGAGGAACC
  AAATGGAAAACTGCCAGGCACTGGTGGATACGTTTCTAAAACTGGACTTGGAGGATCCCACCCTGGACCT
  GGACATTTTCATTAGTCAGGAAGTGCTGCCCGCTGCTCCCACCATCCTCTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001146215
• ORF Size: 2502 bp
• Insert Size: 2502
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001146215.2, NP_001139687.1
• RefSeq Size: 2697
• RefSeq ORF: 2502
• Locus ID: 17687
• Gene Summary: This gene encodes a member of the MutS family of proteins that play critical roles in DNA mismatch repair and meiotic homologous recombination processes. Mice lacking the encoded protein are viable but sterile, with severe defects in spermatogenesis in males and complete loss of ovarian structures in females. Mutations in a similar gene in humans have been shown to cause common variable immune deficiency (CVID) and immunoglobulin A deficiency. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2015]
  Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.