Cse1l (NM_023565) Mouse Untagged Clone

CAT#: MC222918

Cse1l (untagged) - Mouse chromosome segregation 1-like (S. cerevisiae) (Cse1l), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Cse1l
• Synonyms: 2610100P18Rik; AA407533; Capts; Cas; Xpo2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC222918 representing NM_023565
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGCTCAGCGATGCGAATTTACAGACACTAACAGAGTATTTAAAGAAAACCCTGGATCCTGATCCTG
  CCATTAGACGGCCAGCTGAGAAGTTTCTCGAATCCGTAGAAGGAAATCAGAATTACCCACTGTTGCTTTT
  AACATTATTGGAAAAGTCACAGGATAATGTCATTAAAGTATGTGCTTCAGTAACCTTCAAGAACTATATT
  AAAAGGAATTGGAGAATTGTTGAAGATGAACCAAACAAAATTTGCGAAGCTGATCGAGTAGCTATTAAAG
  CCAACATAGTGCATCTGATGCTGAGCAGTCCAGAGCAGATTCAGAAGCAGCTGAGTGATGCTATTAGCAT
  CATTGGCAGAGAAGATTTCCCTCAGAAATGGCCTGACTTGTTGACAGAAATGGTGAATCGCTTTCAGAGT
  GGAGATTTTCACGTCATTAATGGAGTCCTTCGTACAGCGCACTCACTATTTAAGAGATACCGGCATGAGT
  TCAAGTCAAATGAGCTGTGGACTGAAATTAAACTTGTCTTGGATGCCTTTGCTTTGCCTTTGACTAATCT
  ATTCAAGGCCACCATTGAACTGTGCAGTACCCATGCAAATGACGCCTCTGCCCTGAGGATTCTTTTTTCT
  TCCTTGATTTTGATCTCAAAATTGTTCTATAGTTTGAACTTTCAGGATCTCCCTGAATTCTTTGAAGATA
  ATATGGAAACTTGGATGAACAATTTTCATACCCTCCTGACACTGGATAATAAGCTCTTGCAGACTGATGA
  TGAAGAGGAAGCAGGCTTACTGGAGCTTTTAAAGTCTCAGATCTGTGATAATGCCGCTCTCTATGCACAG
  AAATATGACGAAGAGTTTCAGCGGTACCTCCCTCGCTTTGTCACAGCTATCTGGAACTTACTCGTTACAA
  CAGGGCGAGAAGTTAAATATGACTTGTTGGTTAGCAATGCAATTCAGTTTCTGGCTTCAGTTTGTGAAAG
  GCCACATTATAAGAATCTGTTTGAGGACCAGAACACGCTGACAAGTATCTGTGAAAAAGTTATTGTGCCT
  AACATGGAATTTAGAGCTGCTGATGAAGAAGCTTTTGAAGATAATTCTGAGGAGTACATACGGAGGGATT
  TGGAAGGCTCTGATATTGATACTAGACGCAGGGCTGCTTGTGATCTTGTACGAGGATTATGCAAATTTTT
  TGAAGGTCCTGTGACAGGAATCTTCTCTGGTTATGTTAATTCCATGCTCCAGGAGTATGCAAAAAACCCG
  TCTGTCAACTGGAAACACAAAGATGCAGCTATTTACCTTGTCACATCTTTGGCATCAAAAGCCCAGACAC
  AGAAGCATGGAATCACGCAAGCCAATGAACTTGTAAACCTAACTGAATTTTTCGTGAATCACATACTTCC
  TGATTTAAAATCAAATAATGTGAATGAGTTTCCTGTGCTTAAAGCTGATGGTATCAAATATATTATGATT
  TTTAGGAATCAAGTACCAAAAGAGCACCTCCTAGTCTCTATTCCCCTCTTGATCAGTCACCTGGAGGCTG
  AGAGTATTGTCGTCCACACTTATGCCGCACATGCTCTCGAAAGGCTGTTCACTATGAGAGGGTCAAACAA
  TACCACTCTTTTTACAGCTGCAGAAATCGCACCGTTTGTTGAGATTCTGCTAACAAACCTTTTCAAAGCT
  CTCACACTTCCTGGCTCTTCAGAAAATGAATATATTATGAAAGCTATCATGAGAAGTTTCTCCCTCCTGC
  AAGAGGCCATCATCCCCTATATCCCCACTCTCATCACGCAGCTCACACAGAAGCTGCTGGCTGTTAGTAA
  GAATCCCAGTAAACCTCATTTCAATCACTACATGTTTGAAGCAATATGCTTGTCTATAAGAATAACCTGC
  AAAGCTAACCCTGCTGCTGTTGTGAATTTTGAGGAGGCTCTGTTTCTAGTGTTCACTGAGATCTTACAAA
  ATGATGTACAAGAGTTTATCCCATATGTCTTTCAAGTGATGTCTTTACTTCTGGAAACACATAAAAATGA
  TATCCCGTCTTCCTATATGGCCTTGTTTCCCCACCTCCTTCAGCCAGTACTGTGGGAAAGGACAGGAAAC
  ATCCCTGCTCTAGTGAGGCTGCTCCAGGCATTCTTAGAACGAGGCTCAAGTACAATAGCAACTGCTGCAG
  CTGACAAAATTCCTGGATTACTGGGTGTCTTCCAGAAGCTGATTGCATCCAAGGCAAACGATCACCAAGG
  TTTCTATCTTCTCAACAGTATAATCGAACACATGCCTCCTGAATCAGTTGACCAGTATAGGAAGCAGATC
  TTCATTCTACTATTCCAGAGACTGCAAAACTCCAAGACCACCAAGTTTATCAAGAGTTTCTTAGTGTTTA
  TTAACTTATATTGCATTAAGTATGGGGCACTAGCATTACAAGAAATATTTGATGGCATACAACCAAAAAT
  GTTTGGAATGGTTTTGGAAAAAATCATTATTCCAGAGATTCAAAAGGTATCTGGGAACGTGGAGAAAAAA
  ATCTGTGCAGTTGGCATAACCAAATTACTCACAGAGTGTCCACCAATGATGGACACGGAGTACACTAAGC
  TGTGGACTCCTTTGTTACAATCTCTCATTGGCCTGTTTGAATTACCTGAAGATGACAGCATTCCTGATGA
  AGAGCATTTCATTGACATAGAAGATACACCAGGATACCAGACTGCCTTCTCACAGCTGGCATTTGCTGGT
  AAAAAGGAACATGATCCTGTAGGTCAGATGGTAAACAACCCCAAAATCCATCTGGCACAGTCACTTCACA
  AACTGTCAACTGCTTGTCCTGGAAGGGTTCCCTCGATGGTGAGCACCAGCCTCAATGCAGAAGCCTTGCA
  GTATCTCCAAGGTTACCTGCAGGCAGCCAGTGTGACCCTGTTGTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_023565
• ORF Size: 2916 bp
• Insert Size: 2916
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_023565.3, NP_076054.1
• RefSeq Size: 3604
• RefSeq ORF: 2916
• Locus ID: 110750
• Gene Summary: Export receptor for importin-alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates (cargos) have been released into the nucleoplasm. In the nucleus binds cooperatively to importin-alpha and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the importin-alpha from the export receptor. CSE1L/XPO2 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. [UniProtKB/Swiss-Prot Function]