Kl (NM_013823) Mouse Untagged Clone

CAT#: MC223205

Kl (untagged) - Mouse klotho (Kl), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Kl
• Synonyms: alpha-kl
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC223205 representing NM_013823
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCTAGCCCGCGCCCCTCCTCGCCGCCCGCCGCGGCTGGTGCTGCTCCGTTTGCTGTTGCTGCATCTGC
  TGCTGCTCGCCCTGCGCGCCCGCTGCCTGAGCGCTGAGCCGGGTCAGGGCGCGCAGACCTGGGCTCGCTT
  CGCGCGCGCTCCTGCCCCAGAGGCCGCTGGCCTCCTCCACGACACCTTCCCCGACGGTTTCCTCTGGGCG
  GTAGGCAGCGCCGCCTATCAGACCGAGGGCGGCTGGCGACAGCACGGCAAAGGCGCGTCCATCTGGGACA
  CTTTCACCCATCACTCTGGGGCGGCCCCGTCCGACTCCCCGATCGTCGTGGCGCCGTCGGGTGCCCCGTC
  GCCTCCCCTGTCCTCCACTGGAGATGTGGCCAGCGATAGTTACAACAACGTCTACCGCGACACAGAGGGG
  CTGCGCGAACTGGGGGTCACCCACTACCGCTTCTCCATATCGTGGGCGCGGGTGCTCCCCAATGGCACCG
  CGGGCACTCCCAACCGCGAGGGGCTGCGCTACTACCGGCGGCTGCTGGAGCGGCTGCGGGAGCTGGGCGT
  GCAGCCGGTGGTTACCCTGTACCATTGGGACCTGCCACAGCGCCTGCAGGACACCTATGGCGGATGGGCC
  AATCGCGCCCTGGCCGACCATTTCAGGGATTATGCCGAGCTCTGCTTCCGCCACTTCGGTGGTCAGGTCA
  AGTACTGGATCACCATTGACAACCCCTACGTGGTGGCCTGGCACGGGTATGCCACCGGGCGCCTGGCCCC
  GGGCGTGAGGGGCAGCTCCAGGCTCGGGTACCTGGTTGCCCACAACCTACTTTTGGCTCATGCCAAAGTC
  TGGCATCTCTACAACACCTCTTTCCGCCCCACACAGGGAGGCCGGGTGTCTATCGCCTTAAGCTCCCATT
  GGATCAATCCTCGAAGAATGACTGACTATAATATCAGAGAATGCCAGAAGTCTCTTGACTTTGTGCTAGG
  CTGGTTTGCCAAACCCATATTTATTGATGGCGACTACCCAGAGAGTATGAAGAACAACCTCTCGTCTCTT
  CTGCCTGATTTTACTGAATCTGAGAAGAGGCTCATCAGAGGAACTGCTGACTTTTTTGCTCTCTCCTTCG
  GACCAACCTTGAGCTTTCAGCTATTGGACCCTAACATGAAGTTCCGCCAATTGGAGTCTCCCAACCTGAG
  GCAGCTTCTGTCTTGGATAGATCTGGAATATAACCACCCTCCAATATTTATTGTGGAAAATGGCTGGTTT
  GTCTCGGGAACCACCAAAAGGGATGATGCCAAATATATGTATTATCTCAAGAAGTTCATAATGGAAACCT
  TAAAAGCAATCAGACTGGATGGGGTCGACGTCATTGGGTACACCGCGTGGTCGCTCATGGACGGTTTCGA
  GTGGCATAGGGGCTACAGCATCCGGCGAGGACTCTTCTACGTTGACTTTCTGAGTCAGGACAAGGAGCTG
  TTGCCAAAGTCTTCGGCCTTGTTCTACCAAAAGCTGATAGAGGACAATGGCTTTCCTCCTTTACCTGAAA
  ACCAGCCCCTTGAAGGGACATTTCCCTGTGACTTTGCTTGGGGAGTTGTTGACAACTACGTTCAAGTGGA
  CACTACTCTCTCTCAGTTTACTGACCCGAATGTCTATCTGTGGGATGTGCATCACAGTAAGAGGCTTATT
  AAAGTAGACGGGGTTGTAGCCAAGAAGAGAAAACCTTACTGTGTTGATTTCTCTGCCATCCGGCCTCAGA
  TAACCTTACTTCGAGAAATGCGGGTCACCCACTTTCGCTTCTCCCTGGACTGGGCCCTGATCTTGCCTCT
  GGGTAACCAGACCCAAGTGAACCACACGGTTCTGCACTTCTACCGCTGCATGATCAGCGAGCTGGTGCAC
  GCCAACATCACTCCAGTGGTGGCCCTGTGGCAGCCAGCAGCCCCGCACCAAGGCCTGCCACATGCCCTTG
  CAAAACATGGGGCCTGGGAGAACCCGCACACTGCTCTGGCGTTTGCAGACTACGCAAACCTGTGTTTTAA
  AGAGTTGGGTCACTGGGTCAATCTCTGGATCACCATGAACGAGCCAAACACACGGAACATGACCTATCGT
  GCCGGGCACCACCTCCTGAGAGCCCATGCCTTGGCTTGGCATCTGTACGATGACAAGTTTAGGGCGGCTC
  AGAAAGGCAAAATATCCATCGCCTTGCAGGCTGACTGGATAGAACCGGCCTGCCCTTTCTCTCAAAATGA
  CAAAGAAGTGGCCGAGAGAGTTTTGGAATTTGATATAGGCTGGCTGGCAGAGCCTATTTTTGGTTCCGGA
  GATTATCCACGTGTGATGAGGGACTGGCTGAACCAAAAAAACAATTTTCTTTTGCCCTATTTCACCGAAG
  ATGAAAAAAAGCTAGTCCGGGGTTCCTTTGACTTCCTGGCGGTGAGTCATTACACCACCATTCTGGTAGA
  CTGGGAAAAGGAGGATCCGATGAAATACAACGATTACTTGGAGGTACAGGAGATGACTGACATCACATGG
  CTCAACTCTCCCAGTCAGGTGGCAGTGGTGCCTTGGGGGCTGCGCAAAGTGCTCAACTGGCTAAGGTTCA
  AGTACGGAGACCTCCCGATGTATGTGACAGCCAATGGAATCGATGATGACCCCCACGCCGAGCAAGACTC
  ACTGAGGATCTATTATATTAAGAATTATGTGAATGAGGCTCTGAAAGCCTACGTGTTGGACGACATCAAC
  CTTTGTGGCTACTTTGCGTATTCACTTAGTGATCGCTCAGCTCCCAAGTCTGGCTTTTATCGATATGCTG
  CGAATCAGTTTGAGCCCAAACCATCTATGAAACATTACAGGAAAATTATTGACAGCAATGGCTTCCTGGG
  TTCTGGAACACTGGGAAGGTTTTGTCCAGAAGAATACACTGTGTGCACCGAATGTGGATTTTTTCAAACC
  CGGAAGTCTTTGCTGGTCTTCATCTCGTTTCTTGTTTTTACTTTTATTATTTCTCTTGCTCTCATTTTTC
  ACTACTCCAAGAAAGGCCAGAGAAGTTATAAGTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_013823
• ORF Size: 3045 bp
• Insert Size: 3045
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: BC138258, AAI38259
• RefSeq Size: 5124
• RefSeq ORF: 3045
• Locus ID: 16591
• Gene Summary: The Klotho peptide generated by cleavage of the membrane-bound isoform may be an anti-aging circulating hormone which would extend life span by inhibiting insulin/IGF1 signaling. [UniProtKB/Swiss-Prot Function]