Nfasc (NM_001160318) Mouse Untagged Clone

CAT#: MC223780

Nfasc (untagged) - Mouse neurofascin (Nfasc), transcript variant 4, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Nfasc
• Synonyms: AA387016; D430023G06Rik; mKIAA0756; NF
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC223780 representing NM_001160318
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCCAGGCAGCAGGCGCCACCCTGGGTCCACATAGCCCTCATCCTCTTCCTCCTCAGCCTCGGAGGGG
  CCATCGAGATTCCGATGGACCTGACCCAACCCCCAACTATCACCAAGCAGTCCGTGAAGGACCACATCGT
  GGACCCTCGAGATAACATCCTGATTGAATGTGAAGCTAAAGGCAACCCCGCCCCCAGTTTTCACTGGACT
  CGCAACAGCAGATTCTTCAACATTGCCAAGGACCCACGGGTGTCCATGAGGAGGAGATCTGGGACCTTGG
  TGATCGACTTCCGCAGTGGTGGGCGGCCTGAGGAATACGAAGGGGAGTACCAGTGCTTTGCCCGGAACAA
  ATTTGGCACTGCACTTAGCAACCGCATCCGCCTGCAGGTGTCCAAATCTCCCCTGTGGCCCAAGGAAAAC
  CTAGACCCCGTCGTGGTTCAAGAGGGTGCCCCCTTGACACTACAGTGCAACCCCCCACCCGGCCTCCCGT
  CCCCCGTCATCTTCTGGATGAGCAGCTCCATGGAGCCCATCACCCAGGACAAGCGTGTCTCCCAGGGTCA
  CAACGGGGACCTGTACTTCTCCAACGTCATGCTGCAGGACATGCAGACCGACTACAGCTGCAACGCGCGC
  TTTCACTTCACCCACACCATTCAGCAGAAGAACCCCTTCACCCTCAAGGTCCTCACCACCCGAGGAGTTG
  CAGAAAGAACGCCCAGCTTCATGTATCCCCAGGGCACATCGAGCAGTCAGATGGTTCTCCGTGGCATGGA
  CCTGCTGCTGGAATGCATTGCCTCTGGCGTCCCAACACCAGACATTGCATGGTACAAGAAAGGTGGGGAC
  CTCCCATCTAACAAGGCCAAGTTCGAGAACTTTAATAAGGCTCTGCGCATCACCAATGTCTCTGAAGAGG
  ACTCTGGGGAGTATTTCTGCCTGGCCTCCAACAAGATGGGCAGCATCCGGCACACGATCTCGGTGAGAGT
  AAAGGCTGCTCCATACTGGCTGGATGAGCCCAAGAACCTGATCCTGGCTCCTGGGGAAGATGGGAGGCTG
  GTATGCCGAGCCAATGGGAACCCGAAGCCGACCGTGCAGTGGATGGTGAATGGAGAGCCTTTACAATCGG
  CACCACCCAATCCCAACCGTGAGGTAGCTGGAGACACTATCATCTTCCGGGATACTCAGATCAGCAGCAG
  GGCAGTGTACCAATGTAATACATCCAATGAACATGGCTACCTGCTGGCCAATGCCTTCGTCAGCGTGTTA
  GATGTACCCCCTCGGATGCTGTCTGCCCGCAACCAGCTCATCAGGGTGATCCTTTATAACCGGACACGGC
  TGGACTGTCCGTTCTTTGGGTCTCCCATCCCAACACTCCGATGGTTTAAGAATGGGCAAGGAAGCAACCT
  GGATGGCGGTAACTACCACGTCTACGAAAACGGCAGTCTAGAAATCAAGATGATTCGCAAAGAGGACCAA
  GGCATCTACACCTGTGTGGCCACCAACATCCTGGGCAAAGCCGAAAATCAAGTCCGCCTGGAGGTCAAAG
  ACCCCACCAGGATCTACAGGATGCCCGAGGACCAGGTGGCCAAGAGGGGCACCACGGTGCAGCTGGAGTG
  CCGCGTGAAACATGACCCCTCCTTGAAGCTCACAGTCTCCTGGCTGAAGGACGATGAGCCACTCTACATT
  GGAAACAGGATGAAGAAGGAAGATGACTCCCTGACGATCTTCGGAGTGGCAGAGCGGGACCAGGGCAGTT
  ACACGTGTATGGCCAGCACCGAGCTGGACCAGGACCTGGCAAAGGCCTACCTCACTGTTCTAGGGCGACC
  AGACCGACCCAGGGACCTGGAGCTCACTGACCTGGCTGAGAGGAGTGTGAGGCTGACCTGGATCCCAGGG
  GATGACAACAACAGCCCTATCACAGACTACGTCGTTCAGTTTGAAGAGGACCAGTTCCAACCAGGGGTGT
  GGCATGACCACTCCAGGTTCCCAGGCAGCGTCAACTCAGCCGTCCTCCATCTGTCCCCATATGTCAACTA
  CCAATTCAGAGTCATCGCTGTCAACGAGGTTGGGAGCAGCCACCCCAGCCTTCCATCCGAGCGGTACCGA
  ACCAGTGGGGCACCCCCTGAATCTAATCCCAGTGATGTGAAGGGCGAAGGGACAAGAAAGAACAATATGG
  AGATCACGTGGACGCCTATGAATGCTACCTCTGCCTTTGGCCCCAACCTACGCTACATTGTCAAGTGGCG
  ACGGAGAGAGACCCGAGAGACTTGGAACAATGTCACAGTGTGGGGCTCTCGCTACGTGGTGGGGCAGACG
  CCTGTCTACGTTCCCTATGAGATCCGAGTCCAGGCTGAAAATGACTTTGGGAAAGGCCCCGAGCCTGACA
  CCATCATTGGGTACTCCGGAGAAGATTATCCCAGGGCTGCGCCCACTGAAGTTAAAATCCGAGTCCTGAA
  CAGCACAGCCATCAGCCTTCAGTGGAACCGAGTCTACTCTGACACGGTCCAGGGCCAGCTCAGAGAGTAT
  CGAGCTTACTACTGGAGGGAAAGCAGTTTGCTGAAGAACCTGTGGGTGTCTCAGAAGAGACAGCAGGCCA
  GCTTCCCTGGTGACCGTCCCCGGGGCGTGGTGGCCCGCCTGTTCCCCTACAGTAACTACAAGCTGGAGAT
  GGTGGTGGTCAATGGGAGAGGTGACGGGCCTCGAAGTGAAACCAAGGAATTCACCACCCCAGAAGGAGTA
  CCCAGTGCCCCCAGGCGGTTCAGAGTCCGACAGCCCAACCTGGAGACCATCAACCTGGAGTGGGACCACC
  CAGAGCACCCCAACGGAATCCTGATTGGATACATCCTCAGATACGTGCCCTTTAATGGAACCAAACTGGG
  AAAGCAGATGGTGGAAAACTTCTCTCCCAATCAGACCAAGTTCTCTGTGCAGAGAGCAGACCCAGTGTCG
  CGTTACCGCTTCTCCCTCAGTGCCAGGACACAGGTGGGCTCTGGAGAAGCAGCCACAGAGGAGTCCCCAG
  CACCTCCAAATGAAGCTACTCCAACTGCAGCTTACACCAATAACCAGGCAGACATCGCCACCCAGGGCTG
  GTTCATCGGGCTCATGTGTGCCATTGCCCTTCTGGTGCTGATCCTTCTCATCGTCTGCTTCATCAAGAGG
  AGTCGAGGTGGCAAGTACCCAGTGCGGGAAAAGAAGGATGTCCCCTTGGGTCCTGAAGACCCCAAAGAAG
  AAGATGGCTCATTTGACTACAGTGATGAGGACAACAAGCCCCTGCAGGGCAGCCAGACATCTCTGGATGG
  CACCATCAAGCAGCAGGAGAGCGATGACAGCCTGGTGGACTATGGCGAAGGCGGCGAGGGCCAGTTCAAT
  GAAGATGGCTCCTTTATTGGCCAGTACACTGTCAAAAAGGACAAGGAGGAAACGGAGGGCAATGAGAGCT
  CAGAGGCCACATCACCAGTCAATGCCATCTATTCCCTTGCCTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001160318
• ORF Size: 3474 bp
• Insert Size: 3474
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001160318.1, NP_001153790.1
• RefSeq Size: 9647
• RefSeq ORF: 3474
• Locus ID: 269116
• Gene Summary: This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined. [provided by RefSeq, May 2009]
  Transcript Variant: This variant (4) represents use of an alternate promoter and 5' UTR, and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The resulting isoform (4) includes the third fibronectin type 3 (FNIII) repeat, lacks the mucin-like domain, and lacks two segments in the N-terminal and central regions, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.