Insr (NM_010568) Mouse Untagged Clone

CAT#: MC224356

Insr (untagged) - Mouse insulin receptor (Insr), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Insr
• Synonyms: 4932439J01Rik; CD220; D630014A15Rik; IR; IR-A; IR-B
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC224356 representing NM_010568
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGCTTCGGGAGAGGATGTGAGACGACGGCTGTGCCATTGCTGGTGGCCGTGGCCGCGTTGCTGGTGG
  GCACAGCCGGCCACCTGTACCCTGGAGAGGTGTGCCCTGGTATGGACATCCGGAACAACCTGACCAGGCT
  ACATGAGCTGGAGAACTGCTCAGTCATTGAGGGCCATCTGCAGATCCTCCTGATGTTCAAGACCAGACCC
  GAAGATTTCCGAGACCTCAGTTTCCCCAAACTCATCATGATCACAGATTACCTGCTTCTCTTCCGTGTCT
  ATGGTCTGGAAAGTCTGAAAGACCTCTTCCCAAATCTCACAGTCATCCGAGGCTCCCGTCTCTTCTTCAA
  CTATGCCCTGGTTATCTTCGAGATGGTCCACCTGAAGGAGCTGGGGCTTTATAACCTCATGAACATCACC
  CGGGGCTCTGTCCGCATCGAGAAGAATAATGAGCTCTGCTACCTGGCCACTATCGACTGGTCCCGTATCC
  TGGATTCTGTGGAGGACAACTACATTGTACTGAACAAAGATGACAACGAGGAATGTGGGGATGTCTGTCC
  AGGCACCGCCAAGGGCAAGACCAACTGTCCTGCCACTGTCATCAATGGGCAGTTTGTGGAACGGTGCTGG
  ACACACAGTCATTGTCAGAAAGTTTGCCCAACCATCTGTAAGTCACATGGCTGCACAGCTGAAGGCCTGT
  GCTGCCACAAAGAGTGCCTGGGCAACTGTTCGGAACCTGATGACCCCACCAAGTGTGTGGCCTGTCGCAA
  CTTCTATCTGGATGGTCAGTGTGTGGAGACCTGCCCGCCACCCTACTATCACTTCCAGGACTGGCGCTGT
  GTGAACTTCAGCTTCTGCCAAGACCTTCACTTCAAATGCAGGAACTCTCGGAAGCCTGGCTGCCACCAAT
  ACGTCATTCACAACAATAAGTGCATCCCCGAGTGCCCGTCTGGCTATACCATGAATTCCAGCAACTTGAT
  GTGCACCCCATGTCTGGGACCCTGCCCTAAGGTCTGCCAAATCCTCGAAGGTGAGAAGACCATTGATTCT
  GTGACATCTGCCCAGGAGCTCCGAGGCTGCACTGTGATCAACGGTAGCCTGATCATCAACATCCGAGGGG
  GCAACAACCTGGCAGCTGAGCTGGAGGCTAACCTTGGCCTCATTGAAGAAATTTCGGGATTTCTAAAGAT
  CCGCCGCTCCTATGCTCTGGTATCACTTTCTTTCTTCAGGAAGCTACATCTGATTCGAGGAGAGACCTTG
  GAAATTGGGAACTATTCTTTTTATGCCTTGGACAACCAGAACCTGAGGCAACTCTGGGACTGGAGCAAAC
  ACAACCTCACCATCACTCAGGGCAAGCTCTTCTTCCATTACAACCCGAAACTCTGCTTGTCTGAAATTCA
  CAAGATGGAAGAAGTCTCCGGAACTAAGGGCCGTCAGGAGAGGAACGACATTGCCCTGAAGACCAATGGG
  GACCAGGCATCGTGTGAAAATGAATTGCTTAAATTTTCTTTCATTCGGACATCTTTTGACAAGATCCTGT
  TGAGGTGGGAACCCTACTGGCCCCCCGACTTCCGAGATCTCCTGGGATTCATGTTGTTCTACAAAGAGGC
  CCCTTATCAGAATGTGACAGAGTTTGATGGGCAGGATGCTTGTGGCTCCAACAGCTGGACTGTGGTGGAT
  ATTGACCCGCCCCAGAGGTCCAACGACCCCAAGTCTCAGACCCCAAGCCACCCTGGGTGGCTGATGCGGG
  GCCTCAAACCCTGGACCCAATACGCCATCTTTGTGAAGACCTTGGTTACCTTCTCTGATGAACGGCGGAC
  CTATGGAGCCAAAAGTGATATCATCTATGTGCAAACAGATGCCACTAATCCTTCTGTCCCCCTGGATCCC
  ATATCAGTTTCTAATTCCTCATCTCAGATTATCTTAAAGTGGAAGCCCCCCTCTGACCCCAATGGCAACA
  TCACACACTACCTGGTGTACTGGGAGAGGCAAGCAGAGGACAGCGAGCTGTTTGAGCTGGATTATTGTCT
  CAAAGGGCTGAAGCTCCCTTCACGGACCTGGTCCCCACCCTTTGAGTCTGATGATTCTCAGAAGCACAAT
  CAGAGTGAGTATGACGACTCGGCCAGTGAGTGCTGCTCATGCCCTAAGACTGACTCTCAGATCCTGAAGG
  AGCTGGAGGAGTCTTCATTCAGGAAGACCTTCGAGGATTACCTGCACAACGTGGTTTTTGTCCCCAGGCC
  ATCCCGAAAGCGAAGATCCCTTGAAGAGGTGGGGAATGTGACAGCCACCACACTCACACTTCCAGATTTC
  CCCAACGTCTCCTCTACCATTGTGCCCACAAGTCAGGAGGAGCACAGGCCATTTGAGAAAGTGGTGAACA
  AGGAGTCACTTGTCATCTCTGGCCTGAGACACTTCACTGGGTACCGCATTGAGCTGCAGGCATGCAATCA
  AGATTCCCCAGATGAGAGGTGCAGTGTGGCTGCCTACGTCAGTGCCCGGACCATGCCTGAAGCTAAGGCA
  GATGACATCGTTGGCCCTGTGACTCATGAAATCTTTGAGAACAATGTTGTACACTTAATGTGGCAAGAGC
  CAAAGGAACCTAATGGTCTGATTGTGCTATATGAAGTGAGCTATCGCCGATATGGTGATGAGGAGCTGCA
  CCTCTGTGTCTCCCGGAAGCATTTTGCCCTGGAGCGGGGCTGCAGGCTGCGAGGGCTCTCCCCAGGAAAC
  TACAGTGTTCGAGTCCGGGCTACCTCTCTGGCAGGAAATGGCTCCTGGACAGAACCCACCTATTTTTATG
  TGACTGATTATTTAGATGTCCCATCAAATATTGCCAAAATTATCATTGGACCCCTCATCTTTGTCTTCCT
  CTTCAGTGTTGTGATTGGAAGTATTTATCTATTTCTGAGAAAGAGGCAGCCGGATGGGCCAATGGGACCA
  CTGTATGCATCTTCAAACCCTGAGTACCTCAGTGCCAGTGATGTGTTTCCATCTTCTGTGTACGTGCCGG
  ACGAGTGGGAGGTGCCTCGAGAGAAGATCACCCTTCTTCGAGAGCTGGGGCAGGGATCCTTTGGTATGGT
  GTATGAAGGCAATGCCAAGGATATCATCAAGGGTGAGGCAGAGACCCGTGTTGCGGTTAAGACTGTCAAT
  GAGTCAGCCAGTCTTCGAGAACGGATCGAGTTCCTCAATGAGGCATCAGTCATGAAGGGATTCACCTGCC
  ATCATGTGGTCCGCCTTCTTGGGGTGGTATCCAAAGGACAGCCAACGCTGGTAGTGATGGAATTGATGGC
  TCATGGAGACCTGAAAAGTCACCTCCGTTCTCTGAGGCCAGATGCTGAGAATAACCCAGGCCGCCCTCCC
  CCTACCTTGCAAGAAATGATTCAGATGACAGCAGAAATTGCTGATGGCATGGCATACTTGAACGCCAAGA
  AGTTTGTGCACCGGGACCTGGCAGCTCGAAACTGCATGGTTGCCCATGATTTTACTGTCAAAATTGGAGA
  CTTTGGAATGACAAGGGACATCTACGAGACAGATTACTATCGGAAAGGGGGCAAGGGACTGCTTCCTGTG
  AGGTGGATGTCACCTGAGTCCCTGAAGGATGGAGTCTTTACTGCTTCTTCTGATATGTGGTCCTTTGGGG
  TGGTCCTTTGGGAAATCACTAGCCTGGCTGAGCAACCTTATCAAGGCCTGTCTAATGAACAGGTGTTGAA
  GTTTGTCATGGATGGAGGCTATCTGGATCCCCCTGATAACTGTCCAGAGAGACTCACTGACCTGATGCGC
  ATGTGCTGGCAGTTCAACCCCAAGATGAGGCCAACCTTCCTGGAAATCGTCAACCTGCTCAAGGATGACC
  TCCACCCCAGCTTTCCAGAAGTTTCCTTCTTCTACAGCGAGGAGAACAAGGCTCCTGAGAGTGAGGAGCT
  GGAGATGGAGTTTGAAGACATGGAGAATGTCCCGTTGGATCGTTCCTCTCACTGTCAGAGAGAAGAGGCT
  GGGGGCCGGGAGGGAGGGTCCTCACTGAGCATCAAACGGACCTATGATGAACACATCCCCTATACCCACA
  TGAATGGGGGCAAGAAGAACGGACGTGTCCTTACCCTGCCAAGGTCAAACCCTTCCTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_010568
• ORF Size: 4119 bp
• Insert Size: 4119
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_010568.2, NP_034698.2
• RefSeq Size: 9357
• RefSeq ORF: 4119
• Locus ID: 16337
• Gene Summary: This gene encodes a member of the receptor tyrosine kinase family of transmembrane signaling proteins that play important roles in cell differentiation, growth and metabolism. The encoded preproprotein undergoes proteolytic processing to generate alpha and beta chains that form a disulfide-linked heterodimer which, in turn homodimerizes to form a mature, functional receptor. Mice lacking the encoded protein develop severe hyperglycemia and hyperketonemia, and die within a couple of days after birth as a result of diabetic ketoacidosis. [provided by RefSeq, Aug 2016]
  Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter protein (isoform A). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.