Insr (NM_010568) Mouse Untagged Clone

CAT#: MC224356

Insr (untagged) - Mouse insulin receptor (Insr), (10ug)


  "NM_010568" in other vectors (4)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Symbol Insr
Synonyms 4932439J01Rik; CD220; D630014A15Rik; IR; IR-A; IR-B
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>MC224356 representing NM_010568
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGGCTTCGGGAGAGGATGTGAGACGACGGCTGTGCCATTGCTGGTGGCCGTGGCCGCGTTGCTGGTGG
GCACAGCCGGCCACCTGTACCCTGGAGAGGTGTGCCCTGGTATGGACATCCGGAACAACCTGACCAGGCT
ACATGAGCTGGAGAACTGCTCAGTCATTGAGGGCCATCTGCAGATCCTCCTGATGTTCAAGACCAGACCC
GAAGATTTCCGAGACCTCAGTTTCCCCAAACTCATCATGATCACAGATTACCTGCTTCTCTTCCGTGTCT
ATGGTCTGGAAAGTCTGAAAGACCTCTTCCCAAATCTCACAGTCATCCGAGGCTCCCGTCTCTTCTTCAA
CTATGCCCTGGTTATCTTCGAGATGGTCCACCTGAAGGAGCTGGGGCTTTATAACCTCATGAACATCACC
CGGGGCTCTGTCCGCATCGAGAAGAATAATGAGCTCTGCTACCTGGCCACTATCGACTGGTCCCGTATCC
TGGATTCTGTGGAGGACAACTACATTGTACTGAACAAAGATGACAACGAGGAATGTGGGGATGTCTGTCC
AGGCACCGCCAAGGGCAAGACCAACTGTCCTGCCACTGTCATCAATGGGCAGTTTGTGGAACGGTGCTGG
ACACACAGTCATTGTCAGAAAGTTTGCCCAACCATCTGTAAGTCACATGGCTGCACAGCTGAAGGCCTGT
GCTGCCACAAAGAGTGCCTGGGCAACTGTTCGGAACCTGATGACCCCACCAAGTGTGTGGCCTGTCGCAA
CTTCTATCTGGATGGTCAGTGTGTGGAGACCTGCCCGCCACCCTACTATCACTTCCAGGACTGGCGCTGT
GTGAACTTCAGCTTCTGCCAAGACCTTCACTTCAAATGCAGGAACTCTCGGAAGCCTGGCTGCCACCAAT
ACGTCATTCACAACAATAAGTGCATCCCCGAGTGCCCGTCTGGCTATACCATGAATTCCAGCAACTTGAT
GTGCACCCCATGTCTGGGACCCTGCCCTAAGGTCTGCCAAATCCTCGAAGGTGAGAAGACCATTGATTCT
GTGACATCTGCCCAGGAGCTCCGAGGCTGCACTGTGATCAACGGTAGCCTGATCATCAACATCCGAGGGG
GCAACAACCTGGCAGCTGAGCTGGAGGCTAACCTTGGCCTCATTGAAGAAATTTCGGGATTTCTAAAGAT
CCGCCGCTCCTATGCTCTGGTATCACTTTCTTTCTTCAGGAAGCTACATCTGATTCGAGGAGAGACCTTG
GAAATTGGGAACTATTCTTTTTATGCCTTGGACAACCAGAACCTGAGGCAACTCTGGGACTGGAGCAAAC
ACAACCTCACCATCACTCAGGGCAAGCTCTTCTTCCATTACAACCCGAAACTCTGCTTGTCTGAAATTCA
CAAGATGGAAGAAGTCTCCGGAACTAAGGGCCGTCAGGAGAGGAACGACATTGCCCTGAAGACCAATGGG
GACCAGGCATCGTGTGAAAATGAATTGCTTAAATTTTCTTTCATTCGGACATCTTTTGACAAGATCCTGT
TGAGGTGGGAACCCTACTGGCCCCCCGACTTCCGAGATCTCCTGGGATTCATGTTGTTCTACAAAGAGGC
CCCTTATCAGAATGTGACAGAGTTTGATGGGCAGGATGCTTGTGGCTCCAACAGCTGGACTGTGGTGGAT
ATTGACCCGCCCCAGAGGTCCAACGACCCCAAGTCTCAGACCCCAAGCCACCCTGGGTGGCTGATGCGGG
GCCTCAAACCCTGGACCCAATACGCCATCTTTGTGAAGACCTTGGTTACCTTCTCTGATGAACGGCGGAC
CTATGGAGCCAAAAGTGATATCATCTATGTGCAAACAGATGCCACTAATCCTTCTGTCCCCCTGGATCCC
ATATCAGTTTCTAATTCCTCATCTCAGATTATCTTAAAGTGGAAGCCCCCCTCTGACCCCAATGGCAACA
TCACACACTACCTGGTGTACTGGGAGAGGCAAGCAGAGGACAGCGAGCTGTTTGAGCTGGATTATTGTCT
CAAAGGGCTGAAGCTCCCTTCACGGACCTGGTCCCCACCCTTTGAGTCTGATGATTCTCAGAAGCACAAT
CAGAGTGAGTATGACGACTCGGCCAGTGAGTGCTGCTCATGCCCTAAGACTGACTCTCAGATCCTGAAGG
AGCTGGAGGAGTCTTCATTCAGGAAGACCTTCGAGGATTACCTGCACAACGTGGTTTTTGTCCCCAGGCC
ATCCCGAAAGCGAAGATCCCTTGAAGAGGTGGGGAATGTGACAGCCACCACACTCACACTTCCAGATTTC
CCCAACGTCTCCTCTACCATTGTGCCCACAAGTCAGGAGGAGCACAGGCCATTTGAGAAAGTGGTGAACA
AGGAGTCACTTGTCATCTCTGGCCTGAGACACTTCACTGGGTACCGCATTGAGCTGCAGGCATGCAATCA
AGATTCCCCAGATGAGAGGTGCAGTGTGGCTGCCTACGTCAGTGCCCGGACCATGCCTGAAGCTAAGGCA
GATGACATCGTTGGCCCTGTGACTCATGAAATCTTTGAGAACAATGTTGTACACTTAATGTGGCAAGAGC
CAAAGGAACCTAATGGTCTGATTGTGCTATATGAAGTGAGCTATCGCCGATATGGTGATGAGGAGCTGCA
CCTCTGTGTCTCCCGGAAGCATTTTGCCCTGGAGCGGGGCTGCAGGCTGCGAGGGCTCTCCCCAGGAAAC
TACAGTGTTCGAGTCCGGGCTACCTCTCTGGCAGGAAATGGCTCCTGGACAGAACCCACCTATTTTTATG
TGACTGATTATTTAGATGTCCCATCAAATATTGCCAAAATTATCATTGGACCCCTCATCTTTGTCTTCCT
CTTCAGTGTTGTGATTGGAAGTATTTATCTATTTCTGAGAAAGAGGCAGCCGGATGGGCCAATGGGACCA
CTGTATGCATCTTCAAACCCTGAGTACCTCAGTGCCAGTGATGTGTTTCCATCTTCTGTGTACGTGCCGG
ACGAGTGGGAGGTGCCTCGAGAGAAGATCACCCTTCTTCGAGAGCTGGGGCAGGGATCCTTTGGTATGGT
GTATGAAGGCAATGCCAAGGATATCATCAAGGGTGAGGCAGAGACCCGTGTTGCGGTTAAGACTGTCAAT
GAGTCAGCCAGTCTTCGAGAACGGATCGAGTTCCTCAATGAGGCATCAGTCATGAAGGGATTCACCTGCC
ATCATGTGGTCCGCCTTCTTGGGGTGGTATCCAAAGGACAGCCAACGCTGGTAGTGATGGAATTGATGGC
TCATGGAGACCTGAAAAGTCACCTCCGTTCTCTGAGGCCAGATGCTGAGAATAACCCAGGCCGCCCTCCC
CCTACCTTGCAAGAAATGATTCAGATGACAGCAGAAATTGCTGATGGCATGGCATACTTGAACGCCAAGA
AGTTTGTGCACCGGGACCTGGCAGCTCGAAACTGCATGGTTGCCCATGATTTTACTGTCAAAATTGGAGA
CTTTGGAATGACAAGGGACATCTACGAGACAGATTACTATCGGAAAGGGGGCAAGGGACTGCTTCCTGTG
AGGTGGATGTCACCTGAGTCCCTGAAGGATGGAGTCTTTACTGCTTCTTCTGATATGTGGTCCTTTGGGG
TGGTCCTTTGGGAAATCACTAGCCTGGCTGAGCAACCTTATCAAGGCCTGTCTAATGAACAGGTGTTGAA
GTTTGTCATGGATGGAGGCTATCTGGATCCCCCTGATAACTGTCCAGAGAGACTCACTGACCTGATGCGC
ATGTGCTGGCAGTTCAACCCCAAGATGAGGCCAACCTTCCTGGAAATCGTCAACCTGCTCAAGGATGACC
TCCACCCCAGCTTTCCAGAAGTTTCCTTCTTCTACAGCGAGGAGAACAAGGCTCCTGAGAGTGAGGAGCT
GGAGATGGAGTTTGAAGACATGGAGAATGTCCCGTTGGATCGTTCCTCTCACTGTCAGAGAGAAGAGGCT
GGGGGCCGGGAGGGAGGGTCCTCACTGAGCATCAAACGGACCTATGATGAACACATCCCCTATACCCACA
TGAATGGGGGCAAGAAGAACGGACGTGTCCTTACCCTGCCAAGGTCAAACCCTTCCTAA


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Chromatograms CHROMATOGRAMS
Sequencher program is needed, download here.
Restriction Sites SgfI-MluI     
ACCN NM_010568
ORF Size 4119 bp
Insert Size 4119
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Reference Data
RefSeq NM_010568.2, NP_034698.2
RefSeq Size 9357
RefSeq ORF 4119
Locus ID 16337
Gene Summary This gene encodes a member of the receptor tyrosine kinase family of transmembrane signaling proteins that play important roles in cell differentiation, growth and metabolism. The encoded preproprotein undergoes proteolytic processing to generate alpha and beta chains that form a disulfide-linked heterodimer which, in turn homodimerizes to form a mature, functional receptor. Mice lacking the encoded protein develop severe hyperglycemia and hyperketonemia, and die within a couple of days after birth as a result of diabetic ketoacidosis. [provided by RefSeq, Aug 2016]
Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter protein (isoform A). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data.

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