C3 (NM_009778) Mouse Untagged Clone

CAT#: MC224797

C3 (untagged) - Mouse complement component 3 (C3), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: C3
• Synonyms: AI255234; ASP; HSE-MSF; Plp
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC224797 representing NM_009778
  Red=Cloning site Blue=ORF
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGACCAGCTTCAGGGTCCCAGCTACTAGTGCTACTGCTGCTGTTGGCCAGCTCCCCATTAGCTCTGG
  GGATCCCCATGTATTCCATCATTACTCCCAATGTCCTACGGCTGGAGAGCGAAGAGACCATCGTACTGGA
  GGCCCACGATGCTCAGGGTGACATCCCAGTCACAGTCACTGTGCAAGACTTCCTAAAGAGGCAAGTGCTG
  ACCAGTGAGAAGACAGTGTTGACAGGAGCCAGTGGACATCTGAGAAGCGTCTCCATCAAGATTCCAGCCA
  GTAAGGAATTCAACTCAGATAAGGAGGGGCACAAGTACGTGACAGTGGTGGCAAACTTCGGGGAAACGGT
  GGTGGAGAAAGCAGTGATGGTAAGCTTCCAGAGTGGGTACCTCTTCATCCAGACAGACAAGACCATCTAC
  ACCCCTGGCTCCACTGTCTTATATCGGATCTTCACTGTGGACAACAACCTACTGCCCGTGGGCAAGACAG
  TCGTCATCCTCATTGAGACCCCCGATGGCATTCCTGTCAAGAGAGACATTCTGTCTTCCAACAACCAACA
  CGGCATCTTGCCTTTGTCTTGGAACATTCCTGAACTGGTCAACATGGGGCAGTGGAAGATCCGAGCCTTT
  TACGAACATGCGCCGAAGCAGATCTTCTCCGCAGAGTTTGAGGTGAAGGAATACGTGCTGCCCAGTTTTG
  AGGTCCGGGTGGAGCCCACAGAGACATTTTATTACATCGATGACCCAAATGGCCTGGAAGTTTCCATCAT
  AGCCAAGTTCCTGTACGGGAAAAACGTGGACGGGACAGCCTTCGTGATTTTTGGGGTCCAGGATGGCGAT
  AAGAAGATTTCTCTGGCCCACTCCCTCACGCGCGTAGTGATTGAGGATGGTGTGGGGGATGCAGTGCTGA
  CCCGGAAGGTGCTGATGGAGGGGGTACGGCCTTCCAACGCCGACGCCCTGGTGGGGAAGTCCCTGTATGT
  CTCCGTCACTGTCATCCTGCACTCAGGTAGTGACATGGTAGAGGCAGAGCGCAGTGGGATCCCGATTGTC
  ACTTCCCCGTACCAGATCCACTTCACCAAGACACCCAAATTCTTCAAGCCAGCCATGCCCTTTGACCTCA
  TGGTGTTCGTGACCAACCCCGATGGCTCTCCGGCCAGCAAAGTGCTGGTGGTCACTCAGGGATCTAATGC
  AAAGGCTCTCACCCAAGATGATGGCGTGGCCAAGCTAAGCATCAACACACCCAACAGCCGCCAACCCCTG
  ACCATCACAGTCCGCACCAAGAAGGACACTCTCCCAGAATCACGGCAGGCCACCAAGACAATGGAGGCCC
  ATCCCTACAGCACTATGCACAACTCCAACAACTACCTACACTTGTCAGTGTCACGAATGGAGCTCAAGCC
  GGGGGACAACCTCAATGTCAACTTCCACCTGCGCACAGACCCAGGCCATGAGGCCAAGATCCGATACTAC
  ACCTACCTGGTTATGAACAAGGGGAAGCTCCTGAAGGCAGGCCGCCAGGTTCGGGAGCCTGGCCAGGACC
  TGGTGGTCTTGTCCCTGCCCATCACTCCAGAGTTTATTCCTTCATTTCGCCTGGTGGCTTACTACACCCT
  GATTGGAGCTAGTGGCCAGAGGGAGGTGGTGGCTGACTCTGTGTGGGTGGATGTGAAGGATTCCTGTATT
  GGCACGCTGGTGGTGAAGGGTGACCCAAGAGATAACCATCTCGCACCTGGGCAACAAACGACACTCAGGA
  TTGAAGGAAACCAGGGGGCCCGAGTGGGGCTAGTGGCTGTGGACAAGGGAGTGTTTGTGCTGAACAAGAA
  GAACAAACTCACACAGAGCAAGATCTGGGATGTGGTAGAGAAGGCAGACATTGGCTGCACCCCAGGCAGT
  GGGAAGAACTATGCTGGTGTCTTCATGGATGCAGGCCTGGCCTTCAAGACAAGCCAAGGACTGCAGACTG
  AACAGAGAGCAGATCTTGAGTGCACCAAGCCAGCAGCCCGCCGCCGTCGCTCAGTACAGTTGATGGAAAG
  AAGGATGGACAAAGCTGGTCAGTACACTGACAAGGGTCTTCGGAAGTGTTGTGAGGATGGTATGCGGGAT
  ATCCCTATGAGATACAGCTGCCAGCGCCGGGCACGCCTCATCACCCAGGGCGAGAACTGCATAAAGGCCT
  TCATAGACTGCTGCAACCACATCACCAAGCTGCGTGAACAACACAGAAGAGACCACGTGCTGGGCCTGGC
  CAGGAGTGAATTGGAGGAAGACATAATTCCAGAAGAAGATATTATCTCTAGAAGCCACTTCCCACAGAGC
  TGGTTGTGGACCATAGAAGAGTTGAAAGAACCAGAGAAAAATGGAATCTCTACGAAGGTCATGAACATCT
  TTCTCAAAGATTCCATCACCACCTGGGAGATTCTGGCAGTGAGCTTGTCAGACAAGAAAGGGATCTGTGT
  GGCAGACCCCTATGAGATCAGAGTGATGCAGGACTTCTTCATTGACCTGCGGCTGCCCTACTCTGTAGTG
  CGCAACGAACAGGTGGAGATCAGAGCTGTGCTCTTCAACTACCGTGAACAGGAGGAACTTAAGGTGAGGG
  TGGAACTGTTGCATAATCCAGCCTTCTGCAGCATGGCCACCGCCAAGAATCGCTACTTCCAGACCATCAA
  AATCCCTCCCAAGTCCTCGGTGGCTGTACCGTATGTCATTGTCCCCTTGAAGATCGGCCAACAAGAGGTG
  GAGGTCAAGGCTGCTGTCTTCAATCACTTCATCAGTGATGGTGTCAAGAAGACACTGAAGGTCGTGCCAG
  AAGGAATGAGAATCAACAAAACTGTGGCCATCCATACACTGGACCCAGAGAAGCTCGGTCAAGGGGGAGT
  GCAGAAGGTGGATGTGCCTGCCGCAGACCTTAGCGACCAAGTGCCAGACACAGACTCTGAGACCAGAATT
  ATCCTGCAAGGGAGCCCGGTGGTTCAGATGGCTGAAGATGCTGTGGACGGGGAGCGGCTGAAACACCTGA
  TCGTGACCCCCGCAGGCTGTGGGGAACAGAACATGATTGGCATGACACCAACAGTCATTGCGGTACACTA
  CCTGGACCAGACCGAACAGTGGGAGAAGTTCGGCATAGAGAAGAGGCAAGAGGCCCTGGAGCTCATCAAG
  AAAGGGTACACCCAGCAGCTGGCCTTCAAACAGCCCAGCTCTGCCTATGCTGCCTTCAACAACCGGCCCC
  CCAGCACCTGGCTGACAGCCTACGTGGTCAAGGTCTTCTCTCTAGCTGCCAACCTCATCGCCATCGACTC
  TCACGTCCTGTGTGGGGCTGTTAAATGGTTGATTCTGGAGAAACAGAAGCCGGATGGTGTCTTTCAGGAG
  GATGGGCCCGTGATTCACCAAGAAATGATTGGTGGCTTCCGGAACGCCAAGGAGGCAGATGTGTCACTCA
  CAGCCTTCGTCCTCATCGCACTGCAGGAAGCCAGGGACATCTGTGAGGGGCAGGTCAATAGCCTTCCTGG
  GAGCATCAACAAGGCAGGGGAGTATATTGAAGCCAGTTACATGAACCTGCAGAGACCATACACAGTGGCC
  ATTGCTGGGTATGCCCTGGCCCTGATGAACAAACTGGAGGAACCTTACCTCGGCAAGTTTCTGAACACAG
  CCAAAGATCGGAACCGCTGGGAGGAGCCTGACCAGCAGCTCTACAACGTAGAGGCCACATCCTACGCCCT
  CCTGGCCCTGCTGCTGCTGAAAGACTTTGACTCTGTGCCCCCTGTAGTGCGCTGGCTCAATGAGCAAAGA
  TACTACGGAGGCGGCTATGGCTCCACCCAGGCTACCTTCATGGTATTCCAAGCCTTGGCCCAATATCAAA
  CAGATGTCCCTGACCATAAGGACTTGAACATGGATGTGTCCTTCCACCTCCCCAGCCGTAGCTCTGCAAC
  CACGTTTCGCCTGCTCTGGGAAAATGGCAACCTCCTGCGATCGGAAGAGACCAAGCAAAATGAGGCCTTC
  TCTCTAACAGCCAAAGGAAAAGGCCGAGGCACATTGTCGGTGGTGGCAGTGTATCATGCCAAACTCAAAA
  GCAAAGTCACCTGCAAGAAGTTTGACCTCAGGGTCAGCATAAGACCAGCCCCTGAGACAGCCAAGAAGCC
  CGAGGAAGCCAAGAATACCATGTTCCTTGAAATCTGCACCAAGTACTTGGGAGATGTGGACGCCACTATG
  TCCATCCTGGACATCTCCATGATGACTGGCTTTGCTCCAGACACAAAGGACCTGGAACTGCTGGCCTCTG
  GAGTAGATAGATACATCTCCAAGTACGAGATGAACAAAGCCTTCTCCAACAAGAACACCCTCATCATCTA
  CCTAGAAAAGATTTCACACACCGAAGAAGACTGCCTGACCTTCAAAGTTCACCAGTACTTTAATGTGGGA
  CTTATCCAGCCCGGGTCGGTCAAGGTCTACTCCTATTACAACCTCGAGGAATCATGCACCCGGTTCTATC
  ATCCAGAGAAGGACGATGGGATGCTCAGCAAGCTGTGCCACAGTGAAATGTGCCGGTGTGCTGAAGAGAA
  CTGCTTCATGCAACAGTCACAGGAGAAGATCAACCTGAATGTCCGGCTAGACAAGGCTTGTGAGCCCGGA
  GTCGACTATGTGTACAAGACCGAGCTAACCAACATAGAGCTGTTGGATGATTTTGATGAGTACACCATGA
  CCATCCAGCAGGTCATCAAGTCAGGCTCAGATGAGGTGCAGGCAGGGCAGCAACGCAAGTTCATCAGCCA
  CATCAAGTGCAGAAACGCCCTGAAGCTGCAGAAAGGGAAGAAGTACCTCATGTGGGGCCTCTCCTCTGAC
  CTCTGGGGAGAAAAGCCCAACACCAGCTACATCATTGGGAAGGACACGTGGGTGGAGCACTGGCCTGAGG
  CAGAAGAATGCCAGGATCAGAAGTACCAGAAACAGTGCGAAGAACTTGGGGCATTCACAGAATCTATGGT
  GGTTTATGGTTGTCCCAACTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_009778
• ORF Size: 4992 bp
• Insert Size: 4992
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC043338, AAH43338
• RefSeq Size: 5088
• RefSeq ORF: 4992
• Locus ID: 12266
• Gene Summary: This gene encodes complement protein C3 which plays a central role in the classical, alternative and lectin activation pathways of the complement system. The encoded preproprotein undergoes a multi-step processing to generate various functional peptides. Mice deficient in the encoded protein fail to clear bacteria from the blood stream upon infection, display diminished airway hyperresponsiveness and lung eosinophilia upon allergen-induced pulmonary allergy, and develop severe lung injury after deposition of IgG immune complexes. Deficiency of the homolog of the encoded protein in humans was found to be associated with increased susceptibility to infections, age-related macular degeneration, and atypical hemolytic uremic syndrome. [provided by RefSeq, Mar 2015]