Scn2a (NM_001099298) Mouse Untagged Clone

CAT#: MC225118

Scn2a1 (untagged) - Mouse sodium channel, voltage-gated, type II, alpha 1 (Scn2a1), (10ug)


  "NM_001099298" in other vectors (2)

Reconstitution Protocol

USD 3,390.00

10 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Symbol Scn2a
Synonyms 6430408L10; A230052E19Rik; Nav1.2; Scn2a1
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>MC225118 representing NM_001099298
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGCACAATCAGTGCTGGTACCGCCAGGACCTGACAGCTTCCGCTTCTTTACCAGGGAATCCCTTGCTG
CTATTGAACAACGCATTGCAGAAGAGAAAGCTAAGAGACCCAAACAGGAACGCAAGGACGAAGACGACGA
AAATGGCCCAAAGCCAAATAGTGACTTGGAAGCAGGAAAATCCCTTCCTTTTATTTATGGAGACATTCCT
CCAGAGATGGTGTCAGAGCCCCTGGAGGACCTGGACCCCTACTATATCAATAAGAAAACCTTTATAGTAT
TGAATAAAGGGAAAGCAATCTCTCGGTTCAGTGCCACCTCCGCCCTGTACATTTTAACTCCCTTCAACCC
CATTAGAAAATTAGCTATTAAGATTTTGGTACATTCTTTATTCAATGTGCTTATCATGTGCACAATTCTT
ACCAACTGTGTATTTATGACCATGAGCAACCCTCCAGACTGGACAAAGAATGTGGAGTATACTTTTACAG
GAATTTATACTTTTGAATCACTTATTAAAATACTTGCAAGGGGCTTTTGTCTAGAAGATTTCACATTTCT
ACGGGATCCCTGGAACTGGCTGGATTTCACAGTCATTACCTTTGCGTATGTAACAGAATTTGTAAACCTA
GGCAATGTTTCAGCTCTTCGAACTTTCAGAGTCTTGAGAGCTTTGAAAACTATTTCTGTAATTCCAGGCC
TGAAGACCATCGTGGGGGCCCTGATCCAGTCGGTGAAGAAGCTGTCTGACGTCATGATACTCACTGTGTT
CTGTCTGAGTGTCTTTGCTCTCATCGGGCTGCAGCTCTTCATGGGCAACCTGAGGAATAAATGCTTGCAG
TGGCCCCCAGACAATTCTACCTTTGAAATAAACATCACTTCCTTCTTTAATAACTCATTGGATTGGAATG
GTACTGCCTTCAATAGGACAATGAACATGTTTAACTGGGATGAATATATTGAAGATAAAAGTCACTTTTA
TTTTTTGGAAGGACAAAACGATGCTCTGCTTTGTGGTAACAGCTCGGATGCTGGCCAGTGTCCGGAAGGA
TACATCTGTGTGAAGGCTGGGAGAAACCCCAACTATGGCTACACGAGTTTTGACACCTTCAGCTGGGCCT
TCTTGTCCTTATTTCGTCTTATGACTCAAGACTTCTGGGAAAACCTTTATCAGCTGACCTTGCGTGCTGC
TGGGAAAACATATATGATATTTTTCGTGCTTGTGATTTTCTTGGGCTCATTCTACCTAATAAATTTGATC
CTGGCTGTGGTGGCCATGGCCTATGAAGAACAGAACCAGGCCACGCTGGAGGAAGCTGAACAGAAGGAGG
CAGAGTTTCAGCAGATGCTGGAGCAACTTAAGAAGCAGCAAGAAGAAGCTCAGGCAGCAGCTGCAGCAGC
GTCTGCAGAATCCAGAGACTTCAGTGGAGCAGGTGGGATAGGTGTTTTCTCGGAGAGTTCTTCCGTAGCT
TCAAAGTTAAGTTCCAAGAGTGAAAAGGAGCTGAAAAACAGAAGGAAGAAAAAGAAACAGAAAGAGCAGG
CTGGAGAGGAAGAGAAGGAAGATGCTGTGCGGAAATCTGCCTCTGAAGACAGCATACGAAAGAAAGGCTT
CCGGTTTTCCCTAGAAGGGAGTAGACTGACCTACGAGAAGAGGTTTTCCTCTCCACACCAGTCTCTCTTG
AGCATCCGAGGCTCCCTTTTTTCTCCGAGACGCAACAGTAGAGCAAGCCTTTTCAGCTTCAAAGGTCGGG
TGAAGGATATTGGTTCTGAAAATGACTTTGCGGACGATGAACACAGCACGTTTGAGGACAACGACAGCAG
GAGAGACTCTCTATTTGTACCACACAGACATGGAGAAAGGCGTCCCAGCAACGTTAGCCAGGCCAGCCGT
GCCTCCCGGGGGATACCCACTCTACCCATGAATGGGAAGATGCACAGTGCAGTGGACTGCAACGGTGTGG
TCTCCCTAGTTGGAGGCCCTTCTGCTCTCACATCTCCTGTGGGGCAGCTACTACCAGAGGGCACAACTAC
TGAAACAGAAATAAGGAAGAGGAGGTCCAGTTCTTACCATGTTTCTATGGACTTGTTGGAAGACCCTACA
TCAAGGCAAAGAGCAATGAGTATGGCCAGCATTTTGACCAACACTATGGAAGAACTTGAAGAATCCAGAC
AGAAATGCCCTCCATGCTGGTATAAATTTGCTAATATGTGCCTGATTTGGGACTGTTGTAAGCCATGGCT
AAAGGTAAAACATGTTGTCAATCTGGTAGTGATGGATCCATTCGTTGACCTGGCCATCACCATCTGCATT
GTGTTAAATACACTCTTCATGGCCATGGAGCACTACCCGATGACGGAGCAGTTCAGCAGTGTGCTGTCTG
TTGGGAATTTGGTCTTCACTGGGATCTTCACCGCAGAAATGTTTCTCAAGATAATAGCCATGGATCCATA
TTATTACTTTCAAGAAGGCTGGAATATCTTTGATGGCTTTATAGTGAGCCTTAGTTTAATGGAACTCGGC
TTGGCGAATGTGGAAGGACTGTCAGTTCTCCGATCTTTCCGACTGCTTAGAGTCTTCAAGTTGGCAAAAT
CCTGGCCCACACTGAATATGCTCATTAAGATCATCGGCAACTCGGTGGGCGCGCTGGGCAACCTGACCCT
GGTGCTGGCCATCATCGTCTTCATTTTTGCCGTGGTCGGCATGCAGCTGTTTGGAAAGAGCTACAAGGAG
TGTGTTTGCAAGATTTCCAATGATTGTGAGCTGCCGCGCTGGCACATGCATGACTTCTTCCACTCGTTCC
TGATCGTGTTCCGCGTGCTGTGTGGGGAGTGGATAGAGACCATGTGGGACTGCATGGAGGTCGCAGGCCA
GACCATGTGTCTTACTGTCTTCATGATGGTCATGGTGATTGGGAACCTTGTCGTTCTGAACCTCTTCTTG
GCCTTGCTCCTCAGTTCTTTCAGCTCGGACAACCTGGCTGCCACAGATGACGATAACGAAATGAACAACC
TCCAGATAGCCGTGGGAAGGATGCAGAAGGGGATTGATTTTGTTAAAAGGAAGATACGTGAATTCATTCA
GAAAGCCTTTGTCAGAAAGCAGAAAGCTCTAGATGAAATCAAACCCCTTGAAGATCTGAATAACAAGAAA
GACAGTTGTATCTCCAACCACACAACCATAGAAATAGGCAAGGACCTGAATTACCTCAAAGATGGAAACG
GGACGACCAGTGGCATAGGCAGCAGTGTGGAGAAGTACGTGGTAGATGAGAGTGATTACATGTCATTCAT
CAACAACCCCAGCCTCACCGTGACTGTGCCCATTGCTGTGGGAGAGTCTGACTTTGAAAACTTAAATACA
GAAGAATTCAGCAGTGAATCAGATATGGAAGAAAGCAAGGAGAAATTGAATGCAACTAGTTCATCTGAAG
GCAGTACAGTTGATATAGGTGCTCCTGCAGAGGGAGAGCAACCAGAGGCCGAACCAGAAGAGTCCCTTGA
GCCAGAAGCCTGTTTCACAGAAGACTGTGTAAGAAAGTTCAAGTGTTGTCAGATAAGCATAGAAGAAGGC
AAAGGCAAACTCTGGTGGAACTTGAGGAAAACCTGCTACAAGATAGTAGAGCACAACTGGTTTGAAACCT
TCATCGTCTTCATGATTCTGCTCAGCAGCGGTGCTCTGGCCTTTGAAGACATTTACATCGAGCAGCGAAA
AACCATCAAGACCATGCTGGAGTATGCTGACAAGGTCTTCACTTACATCTTCATCCTGGAGATGTTGCTA
AAGTGGGTTGCATATGGTTTCCAAATGTACTTCACCAATGCCTGGTGCTGGCTGGACTTCCTGATCGTTG
ATGTCTCACTGGTTAGCTTAACTGCAAATGCCTTGGGCTATTCAGAACTTGGTGCCATCAAATCCCTCCG
AACATTAAGAGCACTGAGGCCTCTACGAGCCTTATCCCGATTTGAAGGAATGAGGGTTGTTGTAAACGCT
CTCCTAGGTGCAATCCCATCCATAATGAACGTACTTCTGGTCTGCCTGATCTTTTGGCTAATATTCAGTA
TCATGGGGGTGAATCTCTTTGCCGGCAAGTTCTATCATTGCATCAACTACACCACCGGGGAAATGTTTGA
TGTGAGCGTGGTCAACAACTACAGTGAGTGCCAGGCTCTCATAGAGAGCAATCAGACAGCCAGGTGGAAG
AATGTGAAAGTCAACTTTGACAACGTGGGACTTGGATATCTTTCTCTGCTTCAAGTAGCCACATTTAAAG
GATGGATGGATATCATGTATGCAGCTGTTGACTCAAGAAATGTAGAACTGCAACCCAAATATGAAGACAA
TCTATACATGTACCTTTACTTTGTCATCTTTATTATTTTCGGCTCATTCTTCACACTGAACCTGTTCATC
GGCGTCATCATAGATAACTTCAACCAACAGAAGAAGAAGTTTGGAGGTCAAGACATTTTTATGACAGAAG
AACAGAAGAAATACTACAATGCAATGAAGAAGCTAGGCTCAAAGAAACCACAAAAACCGATACCTCGCCC
TGCTAACAAGTTTCAAGGGATGGTCTTTGATTTTGTAACCAAACAAGTGTTTGACATCAGCATCATGATC
CTCATCTGCCTCAACATGGTGACCATGATGGTGGAAACGGACGACCAGAGCCAAGAGATGACCAACATCC
TGTATTGGATCAACCTGGTGTTCATCGTCCTGTTCACCGGCGAGTGTGTGCTCAAGCTTATCTCACTCCG
TCATTATTATTTCACCATTGGATGGAACATTTTTGATTTTGTGGTGGTCATCCTCTCCATTGTAGGGATG
TTTCTCGCGGAGCTGATAGAGAAGTATTTCGTGTCCCCTACCCTGTTCCGAGTCATCCGCCTGGCCAGGA
TTGGACGAATCCTACGCCTGATCAAAGGCGCCAAGGGGATCCGCACGCTGCTCTTTGCTCTGATGATGTC
CCTTCCTGCGCTGTTTAACATCGGCCTCCTGCTTTTCCTGGTCATGTTCATCTACGCCATCTTTGGGATG
TCCAACTTTGCCTACGTTAAGAGGGAAGTTGGGATTGATGACATGTTCAACTTTGAGACCTTTGGCAACA
GCATGATCTGCCTGTTCCAAATCACCACTTCTGCGGGCTGGGATGGACTGCTGGCCCCTATACTAAATAG
TGGACCTCCCGATTGTGACCCTGAAAAAGATCATCCTGGAAGCTCGGTGAAGGGAGACTGTGGGAACCCA
TCTGTGGGGATTTTCTTTTTTGTCAGCTACATCATCATATCCTTCCTGGTTGTGGTGAACATGTACATTG
CTGTCATCCTGGAGAACTTCAGCGTTGCCACAGAAGAAAGTGCAGAGCCTCTGAGTGAGGACGACTTTGA
GATGTTCTACGAAGTCTGGGAGAAGTTCGACCCTGACGCCACCCAGTTCATAGAGTTCTGCAAGCTCTCT
GACTTTGCAGCTGCCCTGGATCCTCCCCTCCTCATCGCAAAGCCAAACAAAGTGCAGCTCATTGCCATGG
ACCTGCCCATGGTGAGTGGAGACCGCATCCACTGCCTGGACATCTTATTTGCTTTTACAAAGCGGGTCCT
GGGTGAGAGTGGAGAGATGGATGCTCTTCGAATCCAGATGGAAGAGCGGTTCATGGCTTCCAATCCCTCC
AAGGTCTCTTATGAGCCCATTACCACCACTCTGAAGCGCAAACAAGAGGAGGTGTCTGCTATTGTCATCC
AGCGAGCTTACAGACGCTATCTTCTGAAACAGAAAGTTAAGAAGGTTTCGTCTATATATAAAAAAGACAA
GGGTAAAGAAGATGAGGGAACGCCCATCAAAGAAGACATCATCACGGATAAACTGAATGAGAATTCAACT
CCAGAGAAGACTGACGTGACACCCTCCACCACTTCGCCACCTTCCTACGATAGCGTGACCAAACCGGAGA
AGGAAAAATTTGAAAAGGACAAATCAGAAAAAGAGGACAAGGGGAAAGATATCAGGGAAAGTAAAAAGTA
A


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI     
ACCN NM_001099298
ORF Size 6021 bp
Insert Size 6021
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_001099298.2, NP_001092768.1
RefSeq Size 8690
RefSeq ORF 6021
Locus ID 110876
Gene Summary Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with four repeat domains, each of which is composed of six membrane-spanning segments, and one or more regulatory beta subunits. Voltage-gated sodium channels are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. In humans, variants of this gene are associated with seizure disorders and autism spectrum disorder. Mice homozygous for a knockout mutation die with severe hypoxia and extensive neuronal cell death, while gain of function mutations result in progressive seizure disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]

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