Scn2a (NM_001099298) Mouse Untagged Clone

CAT#: MC225118

Scn2a1 (untagged) - Mouse sodium channel, voltage-gated, type II, alpha 1 (Scn2a1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Scn2a
• Synonyms: 6430408L10; A230052E19Rik; Nav1.2; Scn2a1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC225118 representing NM_001099298
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCACAATCAGTGCTGGTACCGCCAGGACCTGACAGCTTCCGCTTCTTTACCAGGGAATCCCTTGCTG
  CTATTGAACAACGCATTGCAGAAGAGAAAGCTAAGAGACCCAAACAGGAACGCAAGGACGAAGACGACGA
  AAATGGCCCAAAGCCAAATAGTGACTTGGAAGCAGGAAAATCCCTTCCTTTTATTTATGGAGACATTCCT
  CCAGAGATGGTGTCAGAGCCCCTGGAGGACCTGGACCCCTACTATATCAATAAGAAAACCTTTATAGTAT
  TGAATAAAGGGAAAGCAATCTCTCGGTTCAGTGCCACCTCCGCCCTGTACATTTTAACTCCCTTCAACCC
  CATTAGAAAATTAGCTATTAAGATTTTGGTACATTCTTTATTCAATGTGCTTATCATGTGCACAATTCTT
  ACCAACTGTGTATTTATGACCATGAGCAACCCTCCAGACTGGACAAAGAATGTGGAGTATACTTTTACAG
  GAATTTATACTTTTGAATCACTTATTAAAATACTTGCAAGGGGCTTTTGTCTAGAAGATTTCACATTTCT
  ACGGGATCCCTGGAACTGGCTGGATTTCACAGTCATTACCTTTGCGTATGTAACAGAATTTGTAAACCTA
  GGCAATGTTTCAGCTCTTCGAACTTTCAGAGTCTTGAGAGCTTTGAAAACTATTTCTGTAATTCCAGGCC
  TGAAGACCATCGTGGGGGCCCTGATCCAGTCGGTGAAGAAGCTGTCTGACGTCATGATACTCACTGTGTT
  CTGTCTGAGTGTCTTTGCTCTCATCGGGCTGCAGCTCTTCATGGGCAACCTGAGGAATAAATGCTTGCAG
  TGGCCCCCAGACAATTCTACCTTTGAAATAAACATCACTTCCTTCTTTAATAACTCATTGGATTGGAATG
  GTACTGCCTTCAATAGGACAATGAACATGTTTAACTGGGATGAATATATTGAAGATAAAAGTCACTTTTA
  TTTTTTGGAAGGACAAAACGATGCTCTGCTTTGTGGTAACAGCTCGGATGCTGGCCAGTGTCCGGAAGGA
  TACATCTGTGTGAAGGCTGGGAGAAACCCCAACTATGGCTACACGAGTTTTGACACCTTCAGCTGGGCCT
  TCTTGTCCTTATTTCGTCTTATGACTCAAGACTTCTGGGAAAACCTTTATCAGCTGACCTTGCGTGCTGC
  TGGGAAAACATATATGATATTTTTCGTGCTTGTGATTTTCTTGGGCTCATTCTACCTAATAAATTTGATC
  CTGGCTGTGGTGGCCATGGCCTATGAAGAACAGAACCAGGCCACGCTGGAGGAAGCTGAACAGAAGGAGG
  CAGAGTTTCAGCAGATGCTGGAGCAACTTAAGAAGCAGCAAGAAGAAGCTCAGGCAGCAGCTGCAGCAGC
  GTCTGCAGAATCCAGAGACTTCAGTGGAGCAGGTGGGATAGGTGTTTTCTCGGAGAGTTCTTCCGTAGCT
  TCAAAGTTAAGTTCCAAGAGTGAAAAGGAGCTGAAAAACAGAAGGAAGAAAAAGAAACAGAAAGAGCAGG
  CTGGAGAGGAAGAGAAGGAAGATGCTGTGCGGAAATCTGCCTCTGAAGACAGCATACGAAAGAAAGGCTT
  CCGGTTTTCCCTAGAAGGGAGTAGACTGACCTACGAGAAGAGGTTTTCCTCTCCACACCAGTCTCTCTTG
  AGCATCCGAGGCTCCCTTTTTTCTCCGAGACGCAACAGTAGAGCAAGCCTTTTCAGCTTCAAAGGTCGGG
  TGAAGGATATTGGTTCTGAAAATGACTTTGCGGACGATGAACACAGCACGTTTGAGGACAACGACAGCAG
  GAGAGACTCTCTATTTGTACCACACAGACATGGAGAAAGGCGTCCCAGCAACGTTAGCCAGGCCAGCCGT
  GCCTCCCGGGGGATACCCACTCTACCCATGAATGGGAAGATGCACAGTGCAGTGGACTGCAACGGTGTGG
  TCTCCCTAGTTGGAGGCCCTTCTGCTCTCACATCTCCTGTGGGGCAGCTACTACCAGAGGGCACAACTAC
  TGAAACAGAAATAAGGAAGAGGAGGTCCAGTTCTTACCATGTTTCTATGGACTTGTTGGAAGACCCTACA
  TCAAGGCAAAGAGCAATGAGTATGGCCAGCATTTTGACCAACACTATGGAAGAACTTGAAGAATCCAGAC
  AGAAATGCCCTCCATGCTGGTATAAATTTGCTAATATGTGCCTGATTTGGGACTGTTGTAAGCCATGGCT
  AAAGGTAAAACATGTTGTCAATCTGGTAGTGATGGATCCATTCGTTGACCTGGCCATCACCATCTGCATT
  GTGTTAAATACACTCTTCATGGCCATGGAGCACTACCCGATGACGGAGCAGTTCAGCAGTGTGCTGTCTG
  TTGGGAATTTGGTCTTCACTGGGATCTTCACCGCAGAAATGTTTCTCAAGATAATAGCCATGGATCCATA
  TTATTACTTTCAAGAAGGCTGGAATATCTTTGATGGCTTTATAGTGAGCCTTAGTTTAATGGAACTCGGC
  TTGGCGAATGTGGAAGGACTGTCAGTTCTCCGATCTTTCCGACTGCTTAGAGTCTTCAAGTTGGCAAAAT
  CCTGGCCCACACTGAATATGCTCATTAAGATCATCGGCAACTCGGTGGGCGCGCTGGGCAACCTGACCCT
  GGTGCTGGCCATCATCGTCTTCATTTTTGCCGTGGTCGGCATGCAGCTGTTTGGAAAGAGCTACAAGGAG
  TGTGTTTGCAAGATTTCCAATGATTGTGAGCTGCCGCGCTGGCACATGCATGACTTCTTCCACTCGTTCC
  TGATCGTGTTCCGCGTGCTGTGTGGGGAGTGGATAGAGACCATGTGGGACTGCATGGAGGTCGCAGGCCA
  GACCATGTGTCTTACTGTCTTCATGATGGTCATGGTGATTGGGAACCTTGTCGTTCTGAACCTCTTCTTG
  GCCTTGCTCCTCAGTTCTTTCAGCTCGGACAACCTGGCTGCCACAGATGACGATAACGAAATGAACAACC
  TCCAGATAGCCGTGGGAAGGATGCAGAAGGGGATTGATTTTGTTAAAAGGAAGATACGTGAATTCATTCA
  GAAAGCCTTTGTCAGAAAGCAGAAAGCTCTAGATGAAATCAAACCCCTTGAAGATCTGAATAACAAGAAA
  GACAGTTGTATCTCCAACCACACAACCATAGAAATAGGCAAGGACCTGAATTACCTCAAAGATGGAAACG
  GGACGACCAGTGGCATAGGCAGCAGTGTGGAGAAGTACGTGGTAGATGAGAGTGATTACATGTCATTCAT
  CAACAACCCCAGCCTCACCGTGACTGTGCCCATTGCTGTGGGAGAGTCTGACTTTGAAAACTTAAATACA
  GAAGAATTCAGCAGTGAATCAGATATGGAAGAAAGCAAGGAGAAATTGAATGCAACTAGTTCATCTGAAG
  GCAGTACAGTTGATATAGGTGCTCCTGCAGAGGGAGAGCAACCAGAGGCCGAACCAGAAGAGTCCCTTGA
  GCCAGAAGCCTGTTTCACAGAAGACTGTGTAAGAAAGTTCAAGTGTTGTCAGATAAGCATAGAAGAAGGC
  AAAGGCAAACTCTGGTGGAACTTGAGGAAAACCTGCTACAAGATAGTAGAGCACAACTGGTTTGAAACCT
  TCATCGTCTTCATGATTCTGCTCAGCAGCGGTGCTCTGGCCTTTGAAGACATTTACATCGAGCAGCGAAA
  AACCATCAAGACCATGCTGGAGTATGCTGACAAGGTCTTCACTTACATCTTCATCCTGGAGATGTTGCTA
  AAGTGGGTTGCATATGGTTTCCAAATGTACTTCACCAATGCCTGGTGCTGGCTGGACTTCCTGATCGTTG
  ATGTCTCACTGGTTAGCTTAACTGCAAATGCCTTGGGCTATTCAGAACTTGGTGCCATCAAATCCCTCCG
  AACATTAAGAGCACTGAGGCCTCTACGAGCCTTATCCCGATTTGAAGGAATGAGGGTTGTTGTAAACGCT
  CTCCTAGGTGCAATCCCATCCATAATGAACGTACTTCTGGTCTGCCTGATCTTTTGGCTAATATTCAGTA
  TCATGGGGGTGAATCTCTTTGCCGGCAAGTTCTATCATTGCATCAACTACACCACCGGGGAAATGTTTGA
  TGTGAGCGTGGTCAACAACTACAGTGAGTGCCAGGCTCTCATAGAGAGCAATCAGACAGCCAGGTGGAAG
  AATGTGAAAGTCAACTTTGACAACGTGGGACTTGGATATCTTTCTCTGCTTCAAGTAGCCACATTTAAAG
  GATGGATGGATATCATGTATGCAGCTGTTGACTCAAGAAATGTAGAACTGCAACCCAAATATGAAGACAA
  TCTATACATGTACCTTTACTTTGTCATCTTTATTATTTTCGGCTCATTCTTCACACTGAACCTGTTCATC
  GGCGTCATCATAGATAACTTCAACCAACAGAAGAAGAAGTTTGGAGGTCAAGACATTTTTATGACAGAAG
  AACAGAAGAAATACTACAATGCAATGAAGAAGCTAGGCTCAAAGAAACCACAAAAACCGATACCTCGCCC
  TGCTAACAAGTTTCAAGGGATGGTCTTTGATTTTGTAACCAAACAAGTGTTTGACATCAGCATCATGATC
  CTCATCTGCCTCAACATGGTGACCATGATGGTGGAAACGGACGACCAGAGCCAAGAGATGACCAACATCC
  TGTATTGGATCAACCTGGTGTTCATCGTCCTGTTCACCGGCGAGTGTGTGCTCAAGCTTATCTCACTCCG
  TCATTATTATTTCACCATTGGATGGAACATTTTTGATTTTGTGGTGGTCATCCTCTCCATTGTAGGGATG
  TTTCTCGCGGAGCTGATAGAGAAGTATTTCGTGTCCCCTACCCTGTTCCGAGTCATCCGCCTGGCCAGGA
  TTGGACGAATCCTACGCCTGATCAAAGGCGCCAAGGGGATCCGCACGCTGCTCTTTGCTCTGATGATGTC
  CCTTCCTGCGCTGTTTAACATCGGCCTCCTGCTTTTCCTGGTCATGTTCATCTACGCCATCTTTGGGATG
  TCCAACTTTGCCTACGTTAAGAGGGAAGTTGGGATTGATGACATGTTCAACTTTGAGACCTTTGGCAACA
  GCATGATCTGCCTGTTCCAAATCACCACTTCTGCGGGCTGGGATGGACTGCTGGCCCCTATACTAAATAG
  TGGACCTCCCGATTGTGACCCTGAAAAAGATCATCCTGGAAGCTCGGTGAAGGGAGACTGTGGGAACCCA
  TCTGTGGGGATTTTCTTTTTTGTCAGCTACATCATCATATCCTTCCTGGTTGTGGTGAACATGTACATTG
  CTGTCATCCTGGAGAACTTCAGCGTTGCCACAGAAGAAAGTGCAGAGCCTCTGAGTGAGGACGACTTTGA
  GATGTTCTACGAAGTCTGGGAGAAGTTCGACCCTGACGCCACCCAGTTCATAGAGTTCTGCAAGCTCTCT
  GACTTTGCAGCTGCCCTGGATCCTCCCCTCCTCATCGCAAAGCCAAACAAAGTGCAGCTCATTGCCATGG
  ACCTGCCCATGGTGAGTGGAGACCGCATCCACTGCCTGGACATCTTATTTGCTTTTACAAAGCGGGTCCT
  GGGTGAGAGTGGAGAGATGGATGCTCTTCGAATCCAGATGGAAGAGCGGTTCATGGCTTCCAATCCCTCC
  AAGGTCTCTTATGAGCCCATTACCACCACTCTGAAGCGCAAACAAGAGGAGGTGTCTGCTATTGTCATCC
  AGCGAGCTTACAGACGCTATCTTCTGAAACAGAAAGTTAAGAAGGTTTCGTCTATATATAAAAAAGACAA
  GGGTAAAGAAGATGAGGGAACGCCCATCAAAGAAGACATCATCACGGATAAACTGAATGAGAATTCAACT
  CCAGAGAAGACTGACGTGACACCCTCCACCACTTCGCCACCTTCCTACGATAGCGTGACCAAACCGGAGA
  AGGAAAAATTTGAAAAGGACAAATCAGAAAAAGAGGACAAGGGGAAAGATATCAGGGAAAGTAAAAAGTA
  A
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001099298
• ORF Size: 6021 bp
• Insert Size: 6021
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001099298.2, NP_001092768.1
• RefSeq Size: 8690
• RefSeq ORF: 6021
• Locus ID: 110876
• Gene Summary: Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with four repeat domains, each of which is composed of six membrane-spanning segments, and one or more regulatory beta subunits. Voltage-gated sodium channels are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. In humans, variants of this gene are associated with seizure disorders and autism spectrum disorder. Mice homozygous for a knockout mutation die with severe hypoxia and extensive neuronal cell death, while gain of function mutations result in progressive seizure disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]