Sox17 (NM_001289467) Mouse Untagged Clone

CAT#: MC226835

Sox17 (untagged) - Mouse SRY (sex determining region Y)-box 17 (Sox17), transcript variant 5

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Sox17
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC226835 representing NM_001289467
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCAGGACCACCCCAACTACAAGTACCGGCCGCGGCGGCGCAAGCAGGTGAAGCGCATGAAGCGGGTGG
  AGGGAGGCTTCCTGCACGCTCTCGTCGAGCCCCAGGCCGGCGCGCTTGGTCCCGAGGGCGGCCGCGTGGC
  CATGGATGGCCTGGGTCTGCCTTTCCCGGAGCCGGGCTATCCGGCCGGTCCTCCGCTGATGTCTCCGCAC
  ATGGGCCCCCACTATCGGGACTGCCAGGGACTGGGCGCTCCCGCGCTCGACGGCTACCCTCTGCCCACTC
  CGGACACATCCCCGCTGGATGGCGTGGAGCAGGACCCGGCTTTCTTTGCAGCCCCGCTGCCAGGGGACTG
  CCCGGCGGCCGGCACCTACACTTACGCTCCAGTCTCGGACTATGCAGTGTCCGTAGAGCCGCCCGCTGGC
  CCCATGCGAGTGGGGCCGGACCCCTCGGGCCCTGCGATGCCGGGGATCCTGGCGCCCCCCAGCGCTCTGC
  ACCTGTACTACGGCGCGATGGGCTCGCCCGCCGCAAGTGCGGGGCGCGGTTTCCACGCGCAACCCCAGCA
  GCCGCTGCAACCGCAGGCACCGCCGCCGCCACCGCAGCAGCAGCACCCAGCGCACGGCCCCGGGCAACCT
  TCGCCCCCTCCCGAGGCTCTGCCCTGCCGGGATGGCACGGAATCCAACCAGCCCACTGAGCTCCTAGGGG
  AGGTGGACCGCACGGAATTCGAACAGTATCTGCCCTTTGTGTATAAGCCCGAGATGGGTCTTCCCTACCA
  GGGACACGACTGCGGAGTGAACCTCTCAGACAGCCACGGAGCCATTTCCTCCGTGGTGTCCGACGCTAGC
  TCAGCGGTCTACTATTGCAACTACCCCGACATTTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001289467
• ORF Size: 876 bp
• Insert Size: 876
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This clone expresses the complete ORF with c-terminal tags of Myc-DDK.

Reference Data

• RefSeq: NM_001289467.1, NP_001276396.1
• RefSeq Size: 2897
• RefSeq ORF: 876
• Locus ID: 20671
• Gene Summary: This gene encodes a member of the Sox (Sry-related high mobility group box) family of transcription factors involved in the regulation of embryonic development. The encoded protein plays a role in the determination of cell fate and in maintaining cell identity. This gene regulates tumor angiogenesis and tumor progression. Mutations in the human gene are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
  Transcript Variant: This variant (5) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream start codon compared to variant 1. The resulting isoform (c, also known as t-Sox17; PMID 8636240) has a shorter N-terminus compared to isoform a. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.