Crhr2 (NM_001288620) Mouse Untagged Clone

CAT#: MC226927

Crhr2 (untagged) - Mouse corticotropin releasing hormone receptor 2 (Crhr2), transcript variant 4

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Crhr2
• Synonyms: CRF-R2; Crfr2; CRFR2alpha; CRFR2beta
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC226927 representing NM_001288620
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCATCAAGTACAACACGACCCGGAATGCCTACAGAGAGTGCCTGGAGAACGGGACCTGGGCCTCAAG
  GGTCAACTACTCACACTGCGAACCCATTTTGGATGACAAGGAGTATCCGCTGCCTGAGGAATGTGATCCA
  CTGGAACCTCATCACCACCTTCATTCTGAGAAACATCGCGTGGTTCCTGCTGCAACTCATCGACCACGAA
  GTGCACGAGGGCAATGAGGTCTGGTGCCGCTGCATCACCACCATCTTCAACTATTTTGTGGTCACCAACT
  TCTTCTGGATGTTTGTGGAGGGCTGCTACCTGCACACGGCCATTGTCATGACGTACTCCACAGAGCACCT
  GCGCAAGTGGCTTTTCCTCTTCATTGGATGGTGCATTCCCTGCCCTATCATCATCGCCTGGGCAGTTGGC
  AAACTCTACTATGAGAATGAGCAGTGCTGGTTTGGCAAGGAAGCTGGTGATTTGGTGGACTACATCTACC
  AGGGCCCCGTCATGCTTGTGCTGTTGATCAATTTTGTATTTCTGTTTAACATCGTCAGGATCCTGATGAC
  GAAGTTACGAGCATCCACCACGTCCGAGACAATCCAATACAGGAAGGCAGTGAAGGCCACGCTGGTCCTC
  CTCCCCCTGTTGGGCATCACCTACATGCTCTTCTTTGTCAATCCTGGCGAGGACGACCTGTCCCAGATTG
  TGTTCATCTACTTCAACTCTTTCCTGCAGTCCTTCCAGGGTTTCTTTGTGTCCGTTTTCTACTGCTTCTT
  CAATGGAGAGGTGCGCGCGGCCCTGAGAAAGCGGTGGCACCGCTGGCAGGACCACCACGCCCTCCGGGTG
  CCTGTGGCCCGGGCCATGTCCATCCCTACGTCGCCCACCAGGATCAGCTTCCACAGCATCAAGCAGACAG
  CTGCTGTGTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001288620
• ORF Size: 921 bp
• Insert Size: 921
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This clone expresses the complete ORF with c-terminal tags of Myc-DDK.

Reference Data

• RefSeq: NM_001288620.1, NP_001275549.1
• RefSeq Size: 2497
• RefSeq ORF: 921
• Locus ID: 12922
• Gene Summary: G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (4) differs in the 5' UTR and coding sequence and lacks an alternate coding exon compared to variant 1. The resulting isoform (4) has a shorter and distinct N-terminus compared to isoform 1.